Bacterial Chromatin

Bacterial Chromatin PDF

Author: Remus T. Dame

Publisher: Humana

Published: 2024-08-26

Total Pages: 0

ISBN-13: 9781071639290

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This second edition brings together new and updated methods to explore the structure and function of bacterial chromatin from molecular to the cellular scale. Chapters detail experimental protocols of in vivo and in vitro approaches, approaches to genome structure modeling, and data analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Bacterial Chromatin: Methods and Protocols, Second Edition aims to be a useful up-to-date reference work for researchers currently in the field and to those entering the field.

The Bacterial Chromosome

The Bacterial Chromosome PDF

Author: Karl Drlica

Publisher: ASM Press

Published: 1990

Total Pages: 498

ISBN-13:

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An introduction provides a framework by tracing how some of the major statements about the chromosome have been derived. Contributing authors were encouraged to include instructive material in chapter introductions, to give a sense of direction by engaging in some speculation, and when appropriate, to provide detailed genetic maps. Papers are grouped into six subject areas: primary structure (genetic and physical maps), DNA configuration, chromosome replication and segregation, recombinant and major genetic change, and cryptic genetic information. Nicely produced on coated stock. Member price, $63. Annotation copyrighted by Book News, Inc., Portland, OR

Bacterial Chromatin

Bacterial Chromatin PDF

Author: Remus T. Dame

Publisher: Springer Science & Business Media

Published: 2009-12-24

Total Pages: 447

ISBN-13: 9048134730

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The birth and the development of molecular biology and, subsequently, of genetic engineering and biotechnology cannot be separated from the advancements in our knowledge of the genetics, biochemistry and physiology of bacteria and bacter- phages. Also most of the tools employed nowadays by biotechnologists are of bacterial (or bacteriophage) origin and the playground for most of the DNA manipulations still remains within bacteria. The relative simplicity of the bacterial cell, the short gene- tion times, the well defined and inexpensive culturing conditions which characterize bacteria and the auto-catalytic process whereby a wealth of in-depth information has been accumulated throughout the years have significantly contributed to generate a large number of knowledge-based, reliable and exploitable biological systems. The subtle relationships between phages and their hosts have produced a large amount of information and allowed the identification and characterization of a number of components which play essential roles in fundamental biological p- cesses such as DNA duplication, recombination, transcription and translation. For instance, to remain within the topic of this book, two important players in the or- nization of the nucleoid, FIS and IHF, have been discovered in this way. Indeed, it is difficult to find a single fundamental biological process whose structural and functional aspects are better known than in bacteria.

Dynamics of the Bacterial Chromosome

Dynamics of the Bacterial Chromosome PDF

Author: Wolfgang Schumann

Publisher: John Wiley & Sons

Published: 2006-08-21

Total Pages: 448

ISBN-13: 3527608435

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This book provides an unique overview on bacterial genetics, bacterial genome projects and gene technology and its applicaitons in biological and biomedical research and medicine. The author guides the reader up the front in research within the different fields of bacterial genetics, based mainly on results received with Escherichia coli and Bacillus subtilis.

The Bacterial Chromosome

The Bacterial Chromosome PDF

Author: N. Patrick Higgins

Publisher: Amer Society for Microbiology

Published: 2005

Total Pages: 559

ISBN-13: 9781555812324

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An examination of the mechanisms governing genetic inheritance. - Provides a link between classical experiments in chromosome physiology and new developments in genetic research. - Covers the fundamental systems required for all bacterial cells to replicate chromosomes and organize genetic information. - Presents complex biochemical reactions, including DNA replication, genetic recombination, and RNA transcription, from both genetic and physical perspectives. - Incorporates the implications of the DNA sequence database with information on horizontal gene transfer and the impact of phage genes on bacterial genomes.

Structure and Function of the Bacterial Genome

Structure and Function of the Bacterial Genome PDF

Author: Charles J. Dorman

Publisher: John Wiley & Sons

Published: 2020-04-28

Total Pages: 437

ISBN-13: 1119308798

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Presents an integrated view of the expression of bacterial genetic information, genome architecture and function, and bacterial physiology and pathogenesis This book blends information from the very latest research on bacterial chromosome and nucleoid architecture, whole-genome analysis, cell signaling, and gene expression control with well-known gene regulation paradigms from model organisms (including pathogens) to give readers a picture of how information flows from the environment to the gene, modulating its expression and influencing the competitive fitness of the microbe. Structure and Function of the Bacterial Genome explores the governance of the expression of the genes that make a bacterium what it is, and updates the basics of gene expression control with information about transcription promoter structure and function, the role of DNA as a regulatory factor (in addition to its role as a carrier of genetic information), small RNAs, RNAs that sense chemical signals, ribosomes and translation, posttranslational modification of proteins, and protein secretion. It looks at the forces driving the conservation and the evolution of the dynamic genome and offers chapters that cover DNA replication, DNA repair, plasmid biology, recombination, transposition, the roles of repetitive DNA sequences, horizontal gene transfer, the defense of the genome by CRISPR-Cas, restriction enzymes, Argonaute proteins and BREX systems. The book finishes with a chapter that gives an integrated overview of genome structure and function. Blends knowledge of gene regulatory mechanisms with a consideration of nucleoid structure and dynamics Offers a 'DNA-centric' approach to considering transcription control Views horizontal gene transfer from a gene regulation perspective Assesses the opportunities and limitations of designing synthetic microbes or rewiring existing ones Structure and Function of the Bacterial Genome is an ideal book for graduate and undergraduate students studying microbial cell biology, bacterial pathogenesis, gene regulation, and molecular microbiology. It will also appeal to principal investigators conducting research on these and related topics and researchers in synthetic biology and other arms of biotechnology.

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