Superbugs

Superbugs PDF

Author: Matt McCarthy

Publisher: Penguin

Published: 2020-06-09

Total Pages: 306

ISBN-13: 0735217513

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International Bestseller "An amazing, informative book that changes our perspective on medicine, microbes and our future." --Siddhartha Mukherjee, MD, New York Times bestselling author of The Emperor of All Maladies A New York Times bestselling author shares this exhilarating story of cutting-edge science and the race against the clock to find new treatments in the fight against the antibiotic-resistant bacteria known as superbugs. Physician, researcher, and ethics professor Matt McCarthy is on the front lines of a groundbreaking clinical trial testing a new antibiotic to fight lethal superbugs, bacteria that have built up resistance to the life-saving drugs in our rapidly dwindling arsenal. This trial serves as the backdrop for the compulsively readable Superbugs, and the results will impact nothing less than the future of humanity. Dr. McCarthy explores the history of bacteria and antibiotics, from Alexander Fleming's discovery of penicillin, to obscure sources of innovative new medicines (often found in soil samples), to the cutting-edge DNA manipulation known as CRISPR, bringing to light how we arrived at this juncture of both incredible breakthrough and extreme vulnerability. We also meet the patients whose lives are hanging in the balance, from Remy, a teenager with a dangerous and rare infection, to Donny, a retired New York City firefighter with a compromised immune system, and many more. The proverbial ticking clock will keep readers on the edge of their seats. Can Dr. McCarthy save the lives of his patients infected with the deadly bacteria, who have otherwise lost all hope?

Superbugs

Superbugs PDF

Author: William Hall

Publisher: Harvard University Press

Published: 2018-04-09

Total Pages: 236

ISBN-13: 0674985079

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Antibiotics are powerful drugs that can prevent and treat infections, but they are becoming less effective as a result of drug resistance. Resistance develops because the bacteria that antibiotics target can evolve ways to defend themselves against these drugs. When antibiotics fail, there is very little else to prevent an infection from spreading. Unnecessary use of antibiotics in both humans and animals accelerates the evolution of drug-resistant bacteria, with potentially catastrophic personal and global consequences. Our best defenses against infectious disease could cease to work, surgical procedures would become deadly, and we might return to a world where even small cuts are life-threatening. The problem of drug resistance already kills over one million people across the world every year and has huge economic costs. Without action, this problem will become significantly worse. Following from their work on the Review on Antimicrobial Resistance, William Hall, Anthony McDonnell, and Jim O’Neill outline the major systematic failures that have led to this growing crisis. They also provide a set of solutions to tackle these global issues that governments, industry, and public health specialists can adopt. In addition to personal behavioral modifications, such as better handwashing regimens, Superbugs argues for mounting an offense against this threat through agricultural policy changes, an industrial research stimulus, and other broad-scale economic and social incentives.

The Perfect Predator

The Perfect Predator PDF

Author: Steffanie Strathdee

Publisher: Hachette Books

Published: 2019-02-26

Total Pages: 346

ISBN-13: 0316418072

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An electrifying memoir of one woman's extraordinary effort to save her husband's life-and the discovery of a forgotten cure that has the potential to save millions more. "A memoir that reads like a thriller." -New York Times Book Review "A fascinating and terrifying peek into the devastating outcomes of antibiotic misuse-and what happens when standard health care falls short." -Scientific American Epidemiologist Steffanie Strathdee and her husband, psychologist Tom Patterson, were vacationing in Egypt when Tom came down with a stomach bug. What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world. Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure. A nail-biting medical mystery, The Perfect Predator is a story of love and survival against all odds, and the (re)discovery of a powerful new weapon in the global superbug crisis.

Viruses Vs. Superbugs

Viruses Vs. Superbugs PDF

Author: T. Häusler

Publisher: Springer

Published: 2016-05-24

Total Pages: 307

ISBN-13: 0230552285

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Each year thousands of people die from bacteria resistant to antibiotics. Alternative drugs are urgently needed. A surprising ray of hope from the past are viruses that kill bacteria, but not us. Award-winning science journalist Thomas Häusler investigates how these long-forgotten cures may help sick people today.

Superbugs Strike Back

Superbugs Strike Back PDF

Author: Connie Goldsmith

Publisher: Twenty-First Century Books

Published: 2007-01-01

Total Pages: 116

ISBN-13: 0822566079

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Explains how superbugs came to be, what scientists are doing to fight them, and how you can protect yourself against these microscopic menaces.

Super Bugs

Super Bugs PDF

Author: Michelle Meadows

Publisher: Scholastic Inc.

Published: 2016-06-28

Total Pages: 40

ISBN-13: 0545687594

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Kids who like insects, superheroes, and good fighting evil will love the Super Bugs! The Super Bugs help insects when they are in danger!"Antennae up, eyes down.Buzzing all around the town.Super Bugs, Super Bugs, mighty, mightySuper Bugs!"These heroic insects are ready to fly in and lend a helping hand or wing! The Super Bugs spend all day doing good, and when the day ends..."To the hideout -- cozy nest. Even heroes need to rest."Young insect enthusiasts will enjoy the fun facts for all nineteen insects in Super Bugs: ants, beetles, bumblebees, butterflies, caterpillars, cicadas, cockroaches, crickets, daddy longlegs, dragonflies, fireflies, fleas, grasshoppers, houseflies, mosquitoes, moths, spiders, stinkbugs, and termites.

Superbug

Superbug PDF

Author: Maryn McKenna

Publisher: Simon and Schuster

Published: 2010-03-23

Total Pages: 288

ISBN-13: 9781439171837

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LURKING in our homes, hospitals, schools, and farms is a terrifying pathogen that is evolving faster than the medical community can track it or drug developers can create antibiotics to quell it. That pathogen is MRSA—methicillin-resistant Staphyloccocus aureus—and Superbug is the first book to tell the story of its shocking spread and the alarming danger it poses to us all. Doctors long thought that MRSA was confined to hospitals and clinics, infecting almost exclusively those who were either already ill or old. But through remarkable reporting, including hundreds of interviews with the leading researchers and doctors tracking the deadly bacterium, acclaimed science journalist Maryn McKenna reveals the hidden history of MRSA’s relentless advance—how it has overwhelmed hospitals, assaulted families, and infiltrated agriculture and livestock, moving inexorably into the food chain. Taking readers into the medical centers where frustrated physicians must discard drug after drug as they struggle to keep patients alive, she discloses an explosion of cases that demonstrate how MRSA is growing more virulent, while evolving resistance to antibiotics with astonishing speed. It may infect us at any time, no matter how healthy we are; it is carried by a stunning number of our household pets; and it has been detected in food animals from cows to chickens to pigs. With the sensitivity of a novelist, McKenna portrays the emotional and financial devastation endured by MRSA’s victims, vividly describing the many stealthy ways in which the pathogen overtakes the body and the shock and grief of parents whose healthy children were felled by infection in just hours. Through dogged detective work, she discloses the unheard warnings that predicted the current crisis and lays bare the flaws that have allowed MRSA to rage out of control: misplaced government spending, inadequate public health surveillance, misguided agricultural practices, and vast overuse of the few precious drugs we have left. Empowering readers with the knowledge they need for self-defense, Superbug sounds an alarm: MRSA has evolved into a global emergency that touches almost every aspect of modern life. It is, as one deeply concerned researcher tells McKenna, "the biggest thing since AIDS."

Killer Superbugs

Killer Superbugs PDF

Author: Nancy Day

Publisher: Enslow Publishing

Published: 2001

Total Pages: 132

ISBN-13: 9780766015883

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Not so long ago, antibiotics were considered miracle cures. The introduction of penicillin turned once fatal infections into minor problems. Tuberculosis, a fatal disease of the early twentieth century, seemed to disappear, but the appearance of microbes that are highly resistant to antibiotics in the late twentieth century meant that minor health problems were major again, and tuberculosis re-entered the scene. Author Nancy Day explains the history of antibiotics and how bacteria and protozoas have become resistant to antibiotic treatment. Day also discusses the fight against the overuse and abuse that have made antibiotics less effective.

OECD Health Policy Studies Stemming the Superbug Tide

OECD Health Policy Studies Stemming the Superbug Tide PDF

Author: OECD.

Publisher: Org. for Economic Cooperation & Development

Published: 2019-01-21

Total Pages: 224

ISBN-13: 9789264307582

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Antimicrobial resistance (AMR) is a large and growing problem with the potential for enormous health and economic consequences, globally. As such, AMR has become a central issue at the top of the public health agenda of OECD countries and beyond. In this

Strategies to Overcome Superbug Invasions: Emerging Research and Opportunities

Strategies to Overcome Superbug Invasions: Emerging Research and Opportunities PDF

Author: Chopra, Dimple Sethi

Publisher: IGI Global

Published: 2021-06-25

Total Pages: 319

ISBN-13: 1799803090

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Recently, there has been an upsurge in microbial infections. Extensive and inappropriate usage of antimicrobial drugs in treating infections has led to the evolution of a resistant strain of microorganisms and irreversible immunosuppression in humans. Medical institutions and hospitals require solutions to combat these contagions in order to avoid future epidemics. Strategies to Overcome Superbug Invasions: Emerging Research and Opportunities highlights current research and potential strategies to prevent the emergence and re-emergence of drug-resistant pathogenic microbial strains. The content within this publication examines biosensing, global initiatives, nanomaterials, and alternative therapies. It is designed for microbiologists, biotechnologists, pharmacists, pharmacologists, virologists, formulation scientists, infectious disease specialists, government officials, policymakers, healthcare practitioners, doctors, nurses, hospital directors, researchers, surgeons, and academicians who are seeking research on innovative solutions for multi-drug-resistant infections.