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Magnesium in Human Health and Disease

Author: Ronald Ross Watson

Publisher: Springer Science & Business Media

Published: 2012-09-14

Total Pages: 318

ISBN-13: 1627030433

Magnesium is an essential mineral which is required for growth and survival of humans. Since magnesium is a mineral and not synthesizable it must be obtained through dietary foods and/or supplements. Magnesium in Human Health and Disease reviews the benefits of magnesium supplementation to reach recommended intakes as well as provides new research that suggests how reaching levels above the recommended intakes can promote health and treat various diseases. Magnesium deficiency can cause low serum potassium and calcium levels, retention of sodium, and low circulating levels of regulatory hormones. These changes in nutrients cause neurological and muscular symptoms such as tremor and muscle spasms. Further magnesium deficiency causes loss of appetite, nausea, vomiting, personality changes and death from heart failure. Causes of magnesium deficiency include alcohol abuse, poorly controlled diabetes, excessive or chronic vomiting and/or diarrhea. Thus the effects of inadequate and deficient intakes or levels of magnesium is critical to health and are reviewed by the expert clinicians in this book. Magnesium in Human Health and Disease provides the most current research to support the potential benefits or lack thereof for normal and high supplementation with magnesium. Animal model research and early human trials are reviewed to document other disease states such as hypertension, cholesterol level, type 2 diabetes and cardiovascular disease that would benefit from increased magnesium.

Magnesium in the Central Nervous System

Author: Robert Vink

Publisher: University of Adelaide Press

Published: 2011

Total Pages: 354

ISBN-13: 0987073052

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The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Magnesium Intake and Human Health

Author: Federica Wolf

Publisher: MDPI

Published: 2018-11-16

Total Pages: 183

ISBN-13: 3038973343

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This book is a printed edition of the Special Issue "Magnesium Intake and Human Health" that was published in Nutrients

Interrelations between Essential Metal Ions and Human Diseases

Author: Astrid Sigel

Publisher: Springer Science & Business Media

Published: 2014-01-27

Total Pages: 573

ISBN-13: 9400775008

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MILS-13 provides an up-to-date review on the relationships between essential metals and human diseases, covering 13 metals and 3 metalloids: The bulk metals sodium, potassium, magnesium, and calcium, plus the trace elements manganese, iron, cobalt, copper, zinc, molybdenum, and selenium, all of which are essential for life. Also covered are chromium, vanadium, nickel, silicon, and arsenic, which have been proposed as being essential for humans in the 2nd half of the last century. However, if at all, they are needed only in ultra-trace amounts, and because of their prevalence in the environment, it has been difficult to prove whether or not they are required. In any case, all these elements are toxic in higher concentrations and therefore, transport and cellular concentrations of at least the essential ones, are tightly controlled; hence, their homeostasis and role for life, including deficiency or overload, and their links to illnesses, including cancer and neurological disorders, are thoroughly discussed. Indeed, it is an old wisdom that metals are indispensable for life. Therefore, Volume 13 provides in an authoritative and timely manner in 16 stimulating chapters, written by 29 internationally recognized experts from 7 nations, and supported by more than 2750 references, and over 20 tables and 80 illustrations, many in color, a most up-to-date view on the vibrant research area of the Interrelations between Essential Metal Ions and Human Diseases.

Diet and Health

Author: National Research Council

Publisher: National Academies Press

Published: 1989-01-01

Total Pages: 765

ISBN-13: 0309039940

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Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.

Calcium and Magnesium in Drinking-water

Author: World Health Organization

Publisher: World Health Organization

Published: 2009

Total Pages: 194

ISBN-13: 9241563559

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Can calcium and magnesium ("hardness") in drinking water contribute to preventing disease? This book documents the outputs of an unprecedented group of experts assembled by the World Health Organization to address this question. It includes their comprehensive consensus view on what is known and what is not about the role and possible health benefit of calcium and magnesium in drinking-water. Also included is a series of chapters each authored by internationally renowned experts reviewing the state of the art in different aspects including: global dietary calcium and magnesium intakes; the contribution of drinking water to calcium and magnesium intake; health significance of calcium and magnesium; role of drinking-water in relation to bone metabolism; epidemiological studies and the association of cardiovascular disease risks with water hardness and magnesium in particular; water production; technical issues and economics. In both developed and developing countries, typical diets are often deficient in calcium and magnesium--essential minerals which are necessary for the development of strong bones and teeth, and for cardiovascular function. At the same time, there is evidence that consuming "hard" drinking-water may be associated with reduced risks for some diseases. Climate change and other ongoing changes will increase the use of high tech treatments--for example desalination and reclamation of polluted waters and mean that the issue will be of increasing future importance.

Transdermal Magnesium Therapy

Author: Dr. Mark Sircus

Publisher: iUniverse

Published: 2011-07-07

Total Pages: 360

ISBN-13: 145028356X

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This second edition of Transdermal Magnesium Therapy offers a full medical review of how magnesium affects cancer, the heart, diabetes, the emotions, inflammation, surgery, autism, transdermal medicine, and so much more. Magnesium is nothing short of a miracle; it has the potential to save you from considerable suffering and pain. The information presented here could even save your life. Magnesium is the lamp of life and one of the most important keys to overall health. When applied in the correct way, magnesium offers us a return to strength and vigor. When used in the emergency room, magnesium can save the day for both heart and stroke patients. What you will be introduced to is magnesium oil, a natural concentrated form of magnesium chloride that can be applied directly to the skin for intense effect. When we are deficient in magnesium, over three hundred enzymes in our body are unable to function properly. Magnesium deficiency has been scientifically identified as a critical factor in the onset of a wide variety of diseases. For various reasons and to varying degree, two-thirds or more of the population is magnesium deficient. Learn how to use this powerful secret to good health in Transdermal Magnesium Therapy.

The Magnesium Miracle (Second Edition)

Author: Carolyn Dean, M.D., N.D.

Publisher: Ballantine Books

Published: 2017-08-15

Total Pages: 608

ISBN-13: 0425286711

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Now updated with 30 percent new material, the only comprehensive guide to one of the most essential but often-overlooked minerals, magnesium—which guards against and helps to alleviate heart disease, stroke, osteoporosis, diabetes, depression, arthritis, and asthma Magnesium is an essential nutrient, indispensable to your health and well-being. By adding this mineral to your diet, you are guarding against—and helping to alleviate—such threats as heart disease, stroke, osteoporosis, diabetes, depression, arthritis, and asthma. But despite magnesium’s numerous benefits, many Americans remain dangerously deficient. Updated and revised throughout with the latest research, this amazing guide explains the vital role that magnesium plays in your body and life. Inside you will discover • new findings about the essential role of magnesium in lowering cholesterol • improved methods for increasing magnesium intake and absorption rate • how calcium can increase the risk of heart disease—and how magnesium can lower it • a magnesium-rich eating plan as delicious as it is healthy • information on the link between magnesium and obesity • vitamins and minerals that work with magnesium to treat specific ailments • why paleo, raw food, and green juice diets can lead to magnesium deficiency The Magnesium Miracle, now more than ever, is the ultimate guide to a mineral that is truly miraculous. Praise for The Magnesium Miracle “Dr. Carolyn Dean has been light-years ahead of her time when it comes to the crucial mineral magnesium and its many lifesaving uses. Her work is a gift to humanity. I highly recommend it.”—Christiane Northrup, M.D. “Throughout this volume and with utmost clarity, Dr. Carolyn Dean presents invaluable recommendations—based on the latest magnesium research. Virtually every American can benefit.”—Paul Pitchford, author of Healing with Whole Foods “Dr. Carolyn Dean has the best credentials for bringing solutions to those suffering from the hidden magnesium disorders that affect most of us. This book needs to be read by anyone wishing to improve their quality of life.”—Stephen T. Sinatra, M.D., author of The Sinatra Solution: Metabolic Cardiology

Microbiome in Human Health and Disease

Author: Pallaval Veera Bramhachari

Publisher: Springer Nature

Published: 2021-10-18

Total Pages: 306

ISBN-13: 9811631565

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The book provides an overview on how the microbiome contributes to human health and disease. The microbiome has also become a burgeoning field of research in medicine, agriculture & environment. The readers will obtain profound knowledge on the connection between intestinal microbiota and immune defense systems, medicine, agriculture & environment. The book may address several researchers, clinicians and scholars working in biomedicine, microbiology and immunology. The application of new technologies has no doubt revolutionized the research initiatives providing new insights into the dynamics of these complex microbial communities and their role in medicine, agriculture & environment shall be more emphasized. Drawing on broad range concepts of disciplines and model systems, this book primarily provides a conceptual framework for understanding these human-microbe, animal-microbe & plant-microbe, interactions while shedding critical light on the scientific challenges that lie ahead. Furthermore this book explains why microbiome research demands a creative and interdisciplinary thinking—the capacity to combine microbiology with human, animal and plant physiology, ecological theory with immunology, and evolutionary perspectives with metabolic science.This book provides an accessible and authoritative guide to the fundamental principles of microbiome science, an exciting and fast-emerging new discipline that is reshaping many aspects of the life sciences. These microbial partners can also drive ecologically important traits, from thermal tolerance to diet in a typical immune system, and have contributed to animal and plant diversification over long evolutionary timescales. Also this book explains why microbiome research presents a more complete picture of the biology of humans and other animals, and how it can deliver novel therapies for human health and new strategies.

Magnesium Deficiency in the Pathogenesis of Disease

Author: Mildred S. Seelig

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 495

ISBN-13: 1468491083

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There is a large and rapidly growing body of literature on the importance of mag nesium in biochemical and physiological processes. There is also much evidence that magnesium deficiency, alone and in combination with agents that interfere with its utilization, is associated with functional and structural abnormalities of mem branes, cells, organs, and systems. The manifestations of the changes caused by magnesium deficiency depend upon its extent and duration and on variable factors. Among the conditions that increase the risk of magnesium deficiency are (1) meta bolic factors that affect the absorption, distribution, and excretion of this mineral; (2) disease and therapy; (3) physiologic states that increase requirements for nutrients; and (4) nutritional imbalances. Excesses of nutrients that interfere with the absorption or increase the excretion of magnesium-such as fat, phosphate, sugar, and vitamin D-can contribute to long-lasting relative magnesium deficiency. All have been implicated in several of the diseases considered in this book. Whether their influence on the need for magnesium is a common denominator remains to be investigated further.