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Biological Potential and Medical Use of Secondary Metabolites

Author: Ana M. L Seca

Publisher:

Published: 2019

Total Pages: 284

ISBN-13: 9783039211883

Many macro and micro species, from terrestrial and aquatic environments, produce structurally unique compounds and, in many countries, still are the primary sources of medicines. In fact, secondary metabolites are an important source of chemotherapeutic agents but are also lead compounds for synthetic modification and the optimization of biological activity. Therefore, the exploitation of secondary metabolites, or their inspired synthetic compounds, offers excellent opportunities for the pharmaceutical industry. This Medicines Special Issue focuses on the great potential of secondary metabolites for therapeutic application. The Special Issue contains 16 articles reporting relevant experimental results, and an overview of bioactive secondary metabolites, their biological effects, and new methodologies that improve and accelerate the process of obtained lead compounds with regard to new drug development. We would like to thank all 83 authors, from all over the world, for their valuable contributions to this Special Issue.

Biological Potential and Medical Use of Secondary Metabolites

Author: Ana M. L Seca

Publisher: MDPI

Published: 2019-07-26

Total Pages: 284

ISBN-13: 3039211870

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Lichen Secondary Metabolites

Author: Branislav Ranković

Publisher: Springer

Published: 2019-07-26

Total Pages: 260

ISBN-13: 303016814X

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This revised and extended edition provides in-depth insights into the benefits and untapped potential of lichen-derived bioactive compounds. The whole spectrum of these compounds’ biological and medical functions, from antibiotic to antiviral and anti-carcinogenic properties, is presented. In addition, a new chapter discusses the anti-neurodegenerative and anti-diabetic activities of lichenic secondary metabolites. Given its scope, the book offers a valuable asset for students and researchers in this field.

Plant Metabolites: Methods, Applications and Prospects

Author: Swapna Thacheril Sukumaran

Publisher: Springer Nature

Published: 2020-11-28

Total Pages: 581

ISBN-13: 9811551367

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Food security and the medicinal needs of billions of people around the world are pressing global issues, and the biodiversity and sustainable utilization of plants is of great significance in this context. Further, ethnobotanical studies are vital in the discovery of new drugs from indigenous medicinal plants, and plants with industrially important metabolites need to be cultivated to meet the growing market demand. In addition, the production of plant metabolites under in vitro conditions also has tremendous possibilities. The totipotency of plant cells plays a valuable role in the sustainable utilization of plant resources through cell, tissue and organ culture. At the same time, production can be enhanced using productive cell lines, treatment with elicitors, changing nutritional parameters and metabolic engineering. This book provides state-of-the-art information on biodiversity, conservation, ethnobotany, various aspects of In vitro secondary metabolite production, bioprospecting from various plant groups and drug discovery. It also discusses methods of extracting and characterizing drug leads from plant sources.

Secondary Metabolites

Author: Ramasamy Vijayakumar

Publisher: BoD – Books on Demand

Published: 2018-09-05

Total Pages: 149

ISBN-13: 1789236428

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This book consists of an introductory overview of secondary metabolites, which are classified into four main sections: microbial secondary metabolites, plant secondary metabolites, secondary metabolites through tissue culture technique, and regulation of secondary metabolite production. This book provides a comprehensive account on the secondary metabolites of microorganisms, plants, and the production of secondary metabolites through biotechnological approach like the plant tissue culture method. The regulatory mechanisms of secondary metabolite production in plants and the pharmaceutical and other applications of various secondary metabolites are also highlighted. This book is considered as necessary reading for microbiologists, biotechnologists, biochemists, pharmacologists, and botanists who are doing research in secondary metabolites. It should also be useful to MSc students, MPhil and PhD scholars, scientists, and faculty members of various science disciplines.

Microbial Secondary Metabolites and Biotechnology

Author:

Publisher:

Published: 2022-03-02

Total Pages: 464

ISBN-13: 9783036532462

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Plant Secondary Metabolites

Author: Anil Kumar Sharma

Publisher: Springer Nature

Published: 2022-03-02

Total Pages: 479

ISBN-13: 9811647798

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Plant secondary metabolites are plant-based natural products that display a variety of pharmacological effects. This book discusses the invaluable bioactivity and multifaceted potential of these compounds. The book describes the physico-chemical and biochemical aspects of the plant secondary metabolites along with the chemistry, therapeutics and future perspectives of these plant secondary metabolites. Moreover, the book also discusses about various sources of plant secondary metabolites, and the metabolite determination through various analytical techniques. It further describes the potential applications of plant secondary metabolites as anticancer and chemo preventive agents, their role as cosmetic ingredients and activity in skin cancer therapy. Further chapters emphasize upon the plethora of roles of plant secondary metabolites, including those as antivirals, anti-bacterial, anti-inflammatory drugs, cardioprotective agents etc. The book culminates with chapters on the impact of certain plant secondary metabolites in plant defence and human healthcare. This book is meant for researchers and students in the field of pharmacology and plant sciences. Moreover, this book is also useful for industry experts especially working in the field of herbal therapeutics.

Co-Evolution of Secondary Metabolites

Author: Jean-Michel Mérillon

Publisher: Springer

Published: 2020-02-24

Total Pages: 973

ISBN-13: 9783319963983

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This Reference Work is devoted to plant secondary metabolites and their evolutionary adaptation to different hosts and pests. Secondary metabolites play an important biological role in plants’ defence against herbivores, abiotic stresses and pathogens, and they also attract beneficial organisms such as pollinators. In this work, readers will find a comprehensive review of the phytochemical diversity, modification and adaptation of secondary metabolites, and the consequences of their co-evolution with plant parasites, pollinators, and herbivores. Chapters from expert contributors are organised into twelve sections that collate the current knowledge in intra-/inter-specific diversity in plant secondary metabolites, changes in secondary metabolites during plants’ adaptation to different environmental conditions, and co-evolution of host-parasite metabolites. Among the twelve themed parts, readers will also discover expert analysis on the genetics and chemical ecology evolution of secondary metabolites, and particular attention is also given to allelochemicals, bioactive molecules in plant defence and the evolution of sensory perception in vertebrates. This reference work will appeal to students, researchers and professionals interested in the field of plant pathology, plant breeding, biotechnology, agriculture and phytochemistry.

Seaweeds Secondary Metabolites

Author: Diana Cláudia Pinto

Publisher: MDPI

Published: 2020-02-21

Total Pages: 320

ISBN-13: 3039283006

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Seaweeds are recognized as highly nutritious, and their use in gastronomy is increasing. Their health benefits and their potential to prevent several diseases have also been established. In this Special Issue several health effects are discussed, with more emphasis on their antitumor activity and potential use to treat Alzheimer’s disease. The key bioactive metabolites, from which phlorotannins can be highlighted, are presented, as well as some important in vivo studies. Altogether, the chapters provide in-depth information about the biological activities of seaweed metabolites, contributing to elucidate the health effects of seaweed.

Natural Secondary Metabolites

Author: Márcio Carocho

Publisher: Springer Nature

Published: 2023-02-21

Total Pages: 960

ISBN-13: 3031185870

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This book focuses on the different compounds (polyphenols, sterols, alkaloids terpenes) that arise from the secondary metabolism of plants and fungi and their importance for research and industry. These compounds have been the backbone and inspiration of various industries like the food, pharmaceutical and others to produce synthetic counterparts. Furthermore, many of these compounds are still widely used to carry out specific functions in all these industries. This book offers a compilation of different texts from world leading scientists in the areas of chemistry, biochemistry, plant science, biotechnology which compile information on each group of secondary metabolism compounds, and their most important applications in the food, pharmaceutical, cosmetic and textile industry. By showcasing the best uses of these compounds, the chemistry behind their production in plants and fungi, this book is a valuable resource and a "go to" artifact for various audiences. The new approach this book offers, by linking research and the application of these compounds, makes it interesting as an inspiration for new research or as a hallmark of what has been done in the secondary metabolism of plants and fungi in recent years. Although this book may be technical, it is also enjoyable as an integral reading experience due to a structured and integrated flow, from the origins of secondary metabolism in organisms, to the discovery of their effects, their high intensity research in recent years and translation into various industries. Beyond learning more on their chemistry, synthesis, metabolic pathway, readers will understand their importance to different research and industry.