Tropomyosin

Tropomyosin PDF

Author: Peter Gunning

Publisher: Springer Science & Business Media

Published: 2009-09-30

Total Pages: 323

ISBN-13: 0387857664

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A recent review of one of my grant applications commented on the ‘rediscovery of tropomyosin’. I was tempted to write back in my rebuttal to the reviewer that I didn’t realise it had been lost. Uncharacteristic maturity prevailed and I resisted the temptation, but I was struck by the underlying observation that research on the str- ture and function of tropomyosin has been somewhat invisible, particularly in terms of the cytoskeleton isoforms. So, how can it be that one of the two major components of the actin filament has been so thoroughly overlooked? I suspect that the answer is disappointingly pedestrian. Whereas the biochemistry of the 1980s revealed the potential of tropomyosin isoforms to diversify the function of actin filaments, the subsequent disenchantment with isoform biology in general in the 1990s inhibited growth of this field. With the development of more sophisticated experimental - proaches we are now seeing a growing realisation of the importance of tropomyosin in regulating actin filaments beyond its pivotal role in muscle contraction. The opportunity to edit this book came at a time when we had written several reviews on different aspects of tropomyosin function and I had just finished the background reading for a comprehensive review of tropomyosin biology. I realised that the field was simply beyond the capacity of any one person to do the field j- tice.

Structure and Functions of Contractile Proteins

Structure and Functions of Contractile Proteins PDF

Author: Boris F. Poglazov

Publisher: Academic Press

Published: 2014-06-28

Total Pages: 341

ISBN-13: 1483270866

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Structure and Functions of Contractile Proteins focuses on the analysis of problems on the structure and functions of contractile proteins in which substantial progress has been achieved. The book first offers information on the protein constitution of myofibrils and myosin, including adenosinetriphosphatase activity, reaction with actin, and myosin molecule. The text also ponders on the polymerization of actin, tropomyosin, and the theory of contraction. Discussions focus on model experiments and molecular basis of contraction; structural interrelations of muscle proteins; features of the process of polymerization of actin; and size of the actin molecule. The text elaborates on the contractile proteins of the elementary motor structures of cells, as well as the chemical composition and physicochemical and enzymic properties of flagella and cilia; achromatin apparatus and movement of chromosomes; and structure of the flagella and cilia. Motor apparatus of bacteriophage and features of the movement of protoplasm and the mechanism of permeability are also discussed. The manuscript is a reliable source of data for readers interested in the structure and functions of contractile proteins.

Comprehensive Biophysics

Comprehensive Biophysics PDF

Author:

Publisher: Academic Press

Published: 2012-04-12

Total Pages: 3533

ISBN-13: 0080957188

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Biophysics is a rapidly-evolving interdisciplinary science that applies theories and methods of the physical sciences to questions of biology. Biophysics encompasses many disciplines, including physics, chemistry, mathematics, biology, biochemistry, medicine, pharmacology, physiology, and neuroscience, and it is essential that scientists working in these varied fields are able to understand each other's research. Comprehensive Biophysics, Nine Volume Set will help bridge that communication gap. Written by a team of researchers at the forefront of their respective fields, under the guidance of Chief Editor Edward Egelman, Comprehensive Biophysics, Nine Volume Set provides definitive introductions to a broad array of topics, uniting different areas of biophysics research - from the physical techniques for studying macromolecular structure to protein folding, muscle and molecular motors, cell biophysics, bioenergetics and more. The result is this comprehensive scientific resource - a valuable tool both for helping researchers come to grips quickly with material from related biophysics fields outside their areas of expertise, and for reinforcing their existing knowledge. Biophysical research today encompasses many areas of biology. These studies do not necessarily share a unique identifying factor. This work unites the different areas of research and allows users, regardless of their background, to navigate through the most essential concepts with ease, saving them time and vastly improving their understanding The field of biophysics counts several journals that are directly and indirectly concerned with the field. There is no reference work that encompasses the entire field and unites the different areas of research through deep foundational reviews. Comprehensive Biophysics fills this vacuum, being a definitive work on biophysics. It will help users apply context to the diverse journal literature offering, and aid them in identifying areas for further research Chief Editor Edward Egelman (E-I-C, Biophysical Journal) has assembled an impressive, world-class team of Volume Editors and Contributing Authors. Each chapter has been painstakingly reviewed and checked for consistent high quality. The result is an authoritative overview which ties the literature together and provides the user with a reliable background information and citation resource

Calcium as a Cellular Regulator

Calcium as a Cellular Regulator PDF

Author: Ernesto Carafoli

Publisher: Oxford University Press, USA

Published: 1999

Total Pages: 664

ISBN-13: 9780195094213

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Encompassing all aspects of calcium signalling, from methods of measuring calcium in cells to the molecular mechanisms for decoding its information, this comprehensive book balances historical aspects and state of the art developments.

The Physiotherapist's Pocket Guide to Exercise E-Book

The Physiotherapist's Pocket Guide to Exercise E-Book PDF

Author: Angela Jane Glynn

Publisher: Elsevier Health Sciences

Published: 2009-04-07

Total Pages: 227

ISBN-13: 0702039292

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This book is for therapists involved in exercise therapy for the prevention and treatment of disease. It covers exercise assessment, current prescription guidelines, precautions, exercise design and clinical case studies. The book also includes exercises to increase strength, power, local muscle endurance, range of movement and aerobic capacity and will be relevant to all areas of therapy practice. In addition to the general guidelines, considerations for exercise groups and exercise at home as well as exercise in special patient populations are addressed. This allows therapists who are expert in one area to become familiar with exercise prescription in another. The book underpins therapeutic exercise in general and also addresses specific considerations for particular clinical situations within current guidelines and practical considerations. Underpinning exercise physiology Physical principles of exercise design Guidelines for exercise training Clinical exercise prescription Limitations to exercise in common conditions Example case studies

Disorders of Voluntary Muscle

Disorders of Voluntary Muscle PDF

Author: George Karpati

Publisher: Cambridge University Press

Published: 2001-07-12

Total Pages: 800

ISBN-13: 9780521650625

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Rewritten and redesigned, this remains the one essential text on the diseases of skeletal muscle.

Microfilament Proteins—Advances in Research and Application: 2012 Edition

Microfilament Proteins—Advances in Research and Application: 2012 Edition PDF

Author:

Publisher: ScholarlyEditions

Published: 2012-12-26

Total Pages: 186

ISBN-13: 1464998930

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Microfilament Proteins—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Microfilament Proteins. The editors have built Microfilament Proteins—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Microfilament Proteins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Microfilament Proteins—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.