Translational Surgery

Translational Surgery PDF

Author:

Publisher: Elsevier

Published: 2023-03-22

Total Pages: 770

ISBN-13: 0323906303

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Translational Surgery covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. The reader will come to fully understand important concepts including case-control studies, prospective cohort studies, randomized trials, and reliability studies. Investigators will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in surgical research, and know what is needed for collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the translational research navigate challenging considerations in study design and implementation. The book provides valuable discussions of the critical appraisal of published studies in surgery, allowing the reader to learn how to evaluate the quality of such studies. Thus, they will improve at measuring outcomes; making effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every surgeon or surgical researcher who has ever had a good clinical idea, but not the knowledge of how to test it. Focuses on translational research in Surgery, covering the principles of evidence-based medicine and applying those principles to the design of translational investigations Provides a practical, straightforward approach to help surgeons and researchers navigate challenging aspects of study design and implementation Details valuable discussions on the critical appraisal of published studies in Surgery, allowing the reader to effectively use all types of evidence for patient care

Translational Research in Breast Cancer

Translational Research in Breast Cancer PDF

Author: Dong-Young Noh

Publisher: Springer Nature

Published: 2021-05-13

Total Pages: 630

ISBN-13: 9813296208

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This book describes recent advances in translational research in breast cancer and presents emerging applications of this research that promise to have meaningful impacts on diagnosis and treatment. It introduces ideas and materials derived from the clinic that have been brought to "the bench" for basic research, as well as findings that have been applied back to "the bedside". Detailed attention is devoted to breast cancer biology and cell signaling pathways and to cancer stem cell and tumor heterogeneity in breast cancer. Various patient-derived research models are discussed, and a further focus is the role of biomarkers in precision medicine for breast cancer patients. Next-generation clinical research receives detailed attention, addressing the increasingly important role of big data in breast cancer research and a wide range of other emerging developments. An entire section is also devoted to the management of women with high-risk breast cancer. Translational Research in Breast Cancer will help clinicians and scientists to optimize their collaboration in order to achieve the common goal of conquering breast cancer.

Applied Translational Research in Foot and Ankle Surgery, An issue of Foot and Ankle Clinics of North America, E-Book

Applied Translational Research in Foot and Ankle Surgery, An issue of Foot and Ankle Clinics of North America, E-Book PDF

Author: Don Anderson

Publisher: Elsevier Health Sciences

Published: 2023-02-24

Total Pages: 209

ISBN-13: 0323938523

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In this issue of Foot and Ankle Clinics, guest editor Dr. Don Anderson brings his considerable expertise to the topic of Applied Translational Research in Foot and Ankle Surgery. Applied translational research is designed to ensure the highest possible chance of success, and in this issue, top experts in foot and ankle surgery help you produce more meaningful, applicable results that take both safety and efficacy into consideration. Contains 14 practice-oriented topics including utilizing novel in-clinic assessments to identify aberrant foot biomechanics; foot and ankle alignment and biomechanical implications; patient-specific FE analysis of foot and ankle biomechanics; biomechanics of chronic ankle instability; and more. Provides in-depth clinical reviews on applied translational research in foot and ankle surgery, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Clinical Image-Based Procedures. Translational Research in Medical Imaging

Clinical Image-Based Procedures. Translational Research in Medical Imaging PDF

Author: Marius Erdt

Publisher: Springer

Published: 2014-03-28

Total Pages: 171

ISBN-13: 3319056662

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This book constitutes revised selected papers from the International Workshop on Clinical Image-Based Procedures, CLIP 2013, held in conjunction with MICCAI 2012 in Nagoya, Japan, in September 2013. The 19 papers presented in this volume were carefully reviewed and selected from 26 submissions. The workshop was a productive and exciting forum for the discussion and dissemination of clinically tested, state-of-the-art methods for image-based planning, monitoring and evaluation of medical procedures.

Clinical Image-Based Procedures. Translational Research in Medical Imaging

Clinical Image-Based Procedures. Translational Research in Medical Imaging PDF

Author: Raj Shekhar

Publisher: Springer

Published: 2016-10-14

Total Pages: 85

ISBN-13: 3319464728

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This book constitutes the revised selected papers from the 5th International Workshop on Clinical Image-Based Procedures, CLIP 2016, held in conjunction with MICCAI 2016 in Athens, Greece, in October 2016. The 10 papers presented in this volume were carefully reviewed and selected from 16 submissions. Specific topics include various image segmentation and registration techniques, applied to various parts of the body. They range from interventional planning to navigation of devices and navigation to the anatomy of interest. Clinical applications cover the skull, the cochlea, cranial nerves, the aortic valve, wrists, and the abdomen, among others.

Translational Cancer Research for Surgeons, An Issue of Surgical Oncology Clinics

Translational Cancer Research for Surgeons, An Issue of Surgical Oncology Clinics PDF

Author: William G. Cance

Publisher: Elsevier Health Sciences

Published: 2013-10-28

Total Pages: 311

ISBN-13: 0323227457

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This issue of the Surgical Oncology Clinics of North America, Guest Edited by Dr. William G. Cance, is devoted to Translational Cancer Research for Surgeons. Translational Cancer research aims to move bench research to the bedside by applying basic science toward potential therapies. This issue will present the concepts of translational research and development of targeted therapeutics, and its implications for surgeons. It will show clinical applications for surgeons regarding sarcoma/GIST, melanoma, colorectal cancer, breast cancer, and endocrine cancer.

Translational Cancer Research for Surgeons, An Issue of Surgical Oncology Clinics

Translational Cancer Research for Surgeons, An Issue of Surgical Oncology Clinics PDF

Author: William G. Cance

Publisher: Elsevier Health Sciences

Published: 2013-09-19

Total Pages: 311

ISBN-13: 0323227449

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This issue of the Surgical Oncology Clinics of North America, Guest Edited by Dr. William G. Cance, is devoted to Translational Cancer Research for Surgeons. Translational Cancer research aims to move bench research to the bedside by applying basic science toward potential therapies. This issue will present the concepts of translational research and development of targeted therapeutics, and its implications for surgeons. It will show clinical applications for surgeons regarding sarcoma/GIST, melanoma, colorectal cancer, breast cancer, and endocrine cancer.

Translational Orthopedics

Translational Orthopedics PDF

Author: Jeffrey A. Bakal

Publisher: Elsevier

Published: 2024-04-26

Total Pages: 580

ISBN-13: 0323885624

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Translational Orthopedics: Designing and Conducting Translational Research covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. The reader will come to fully understand important concepts including case-control study, prospective cohort study, randomized trial, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in translational orthopedics, and know what is needed in collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation. The book provides valuable discussions of the critical appraisal of published studies in translational orthopedics, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every Medical Researcher or Orthopedist who has ever had a good clinical idea but not the knowledge of how to test it. Focuses on the principles of evidence-based medicine and applies these principles to the design of translational investigations within orthopedics Provides a practical, straightforward approach that helps investigators navigate challenging considerations in study design and implementation Details discussions of the critical appraisal of published studies in translational orthopedics, supporting evaluation with respect to measuring outcomes and making effective use of all types of evidence in patient care

Translational Stem Cell Research

Translational Stem Cell Research PDF

Author: Kristina Hug

Publisher: Springer Science & Business Media

Published: 2010-12-25

Total Pages: 462

ISBN-13: 1607619598

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For many years, the ethical discussion surrounding human embryonic stem cell research has focused on the moral status of the embryo. This text takes a wider moral berth and focuses on numerous ethical, legal and social aspects involved in translating the results of stem cell research into diagnostic and therapeutic applications. Translational Stem Cell Research is broken into ten sections. It opens with an overview of the latest in stem cell research, focusing on specific diseases and the treatment of burn victims. Part II discusses the issues involved in the many steps from bench to bedside, ranging from first research in vitro to clinical trials. Part III covers scientific, regulatory and ethical challenges to basic research, and Part IV details issues regarding stem cell banks. Part V explores ethical, economic and strategic issues involved in collaboration between universities and industry, and Part VI addresses legal problems raised by patents on human stem-cell based inventions plus the extent to which there can be technological solutions to a moral dilemma. Part VII presents imaginative ways of communicating research to the general public and how to create conditions for a constructive dialogue. Part VIII probes psychosocial and cultural factors affecting judgment and decisions about translational stem cell research, and Part IX explores problems and procedures raised by an examination of the evaluation of stem cell research projects in research ethics committees. The book closes with a look into the future of translational stem cell research and stem cell-based therapeutic applications.