Toxicology of the Gastrointestinal Tract

Toxicology of the Gastrointestinal Tract PDF

Author: Shayne Cox Gad

Publisher: CRC Press

Published: 2007-01-23

Total Pages: 378

ISBN-13: 1420004263

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Toxicology of the Gastrointestinal Tract focuses on the specifics of the mechanisms and adverse effects of xenobiotic agents and pharmaceuticals on the structure and function of the GI tract. The book focuses on a number of specific areas of intestinal research. Beginning with the well-recognized and major functions of nutrient absorption and its r

Toxicology of the Gastrointestinal Tract, Second Edition

Toxicology of the Gastrointestinal Tract, Second Edition PDF

Author: Shayne Cox Gad

Publisher: CRC Press

Published: 2018-10-26

Total Pages: 477

ISBN-13: 042978144X

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Nanoparticles as both potential unique risks and as a valuable approach to increased and higher specificity in delivery of therapeutics A primer on the largest, most diverse, and important microbiome in any mammal "Tricks of the trade" on modifying the oral administration of drugs

Comprehensive Toxicology, Volume 9

Comprehensive Toxicology, Volume 9 PDF

Author: R.S. McCuskey

Publisher: Pergamon

Published: 1999-08-04

Total Pages: 0

ISBN-13: 9780080429748

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This volume, which is separated into two parts, presents important new information concerning mechanisms of effect and consequences of exposure of the liver and gastrointestinal tract to a wide variety of toxicants. Both sections on the liver and GI tract provide the reader with concise introductory descriptions of relevant cellular and organ anatomy, physiology, and mechanisms of toxic injury. Specific consideration is given to methods of toxin exposure and to processes that provide defence against injury. The discussions provide a broad focus but also contain details about molecular, cellular, and biochemical mechanisms. The section on the liver (34 chapters) provides a comprehensive review of the toxic effects of a wide variety of specific compounds including volatile hydrocarbons, anesthetic agents, drugs of therapeutic value as well as of abuse, heavy metals, natural compounds etc. The section on the gastrointestinal tract (15 chapters), presenting toxicology of the esophagus, stomach, small intestine, and colon, represents the first major reference work available that provides both a broad overview of the effect of toxicants on the mucosal, motility, and immune functions of the GI tract as well as specific information about specific toxicants. The final chapter presents an overview of clinical toxicology in animals with specific focus on the liver and gastrointestinal systems. This volume is of specific interest and use to those concerned with environmental and industrial toxicology, as well as with mechanisms of toxicant injury and clinical medicine.

Comprehensive Toxicology

Comprehensive Toxicology PDF

Author:

Publisher: Elsevier

Published: 2010-06-01

Total Pages: 6448

ISBN-13: 0080468845

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An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today. Contents updated and revised to reflect developments in toxicology research Organized with a unique organ-system approach Features full color throughout Available electronically on sciencedirect.com, as well as in a limited-edition print version

Comprehensive Toxicology, Volume 9

Comprehensive Toxicology, Volume 9 PDF

Author: R.S. McCuskey

Publisher: Pergamon

Published: 1999-08-18

Total Pages: 750

ISBN-13: 9780080429748

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This volume, which is separated into two parts, presents important new information concerning mechanisms of effect and consequences of exposure of the liver and gastrointestinal tract to a wide variety of toxicants. Both sections on the liver and GI tract provide the reader with concise introductory descriptions of relevant cellular and organ anatomy, physiology, and mechanisms of toxic injury. Specific consideration is given to methods of toxin exposure and to processes that provide defence against injury. The discussions provide a broad focus but also contain details about molecular, cellular, and biochemical mechanisms. The section on the liver (34 chapters) provides a comprehensive review of the toxic effects of a wide variety of specific compounds including volatile hydrocarbons, anesthetic agents, drugs of therapeutic value as well as of abuse, heavy metals, natural compounds etc. The section on the gastrointestinal tract (15 chapters), presenting toxicology of the esophagus, stomach, small intestine, and colon, represents the first major reference work available that provides both a broad overview of the effect of toxicants on the mucosal, motility, and immune functions of the GI tract as well as specific information about specific toxicants. The final chapter presents an overview of clinical toxicology in animals with specific focus on the liver and gastrointestinal systems. This volume is of specific interest and use to those concerned with environmental and industrial toxicology, as well as with mechanisms of toxicant injury and clinical medicine.

Gastrointestinal Pharmacology

Gastrointestinal Pharmacology PDF

Author: Beverley Greenwood-Van Meerveld

Publisher: Springer

Published: 2017-04-19

Total Pages: 444

ISBN-13: 3319563602

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This volume aims to connect current ideas and concepts about GI disorders with the search for novel therapeutics. Towards this goal, authors provide a timely state-of-the-art overview of the GI tract in health and disease, current treatment approaches and ongoing developments in drug discovery, and their potential for the better treatment of patients with GI disorders.

Role of gut bacteria in human toxicology and pharmacology

Role of gut bacteria in human toxicology and pharmacology PDF

Author: Bradley Hillman

Publisher: CRC Press

Published: 1995-04-27

Total Pages: 286

ISBN-13: 1482272482

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An examination of the composition and metabolic activity of microorganisms commonly found in the human gut. Chapters cover the effects gut flora have on ingested compounds, vitamin production and gastrointestinal disorders. Comparisons are also made between microbial and mammalian metabolism.

Biological Toxins and Bioterrorism

Biological Toxins and Bioterrorism PDF

Author: P. Gopalakrishnakone

Publisher: Springer

Published: 2015-01-22

Total Pages: 0

ISBN-13: 9789400758681

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Biological toxins are an important part of our world, a reality with which we need to cope, so in parallel with understanding their mechanisms of action and thereby improving our fundamental knowledge, there are successful efforts to utilize them as therapeutics against some debilitating human and animal diseases. In view of the complexity of different types of biotoxins and the broad range of toxin structure, physiology, utility, and countermeasures including regulatory issues, it was thus aimed to compile a book on biotoxins and bioweapons. This reference work in the Toxinology handbook series gathers together knowledge from around the globe about naturally inspired and manufactured biological weapons. The authors describe how they work; how authorities may detect their presence, prevent their use, and diagnose their impacts; and the means by which medical and paramedical professionals may treat victims. Also described are how they have been used to further our knowledge and what insights they have given us into evolutionary and physiological processes. Finally, it is also discussed how these toxins can be used as therapeutics and what the implications of such therapeutics are to their use as biothreat agents. This volume provides a reference accessible to scientists, educators, and medical experts alike with an interest in biotoxins, focusing on the major toxins used as bioweapons. Regulatory agencies will also benefit from the information provided in this book. Some in the intended audience may need to understand how they elicit their effects and how we can defend ourselves against them. Others may be interested in the sometimes colorful histories that surround this subset of biotoxins that can be and, in some cases, have been used as weapons.