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Author: Stanley E. Manahan
Publisher: Springer
Published: 1989
Total Pages: 344
ISBN-13:
DOWNLOAD EBOOK →Manahan, (chemistry, U. of Missouri), covers the major health effects of toxic substances, critical dose/response relationships, the chemistry of toxic substances, and structure activity relationships. Includes terms and classifications of toxicology. Acidic paper. Annotation copyrighted by Book News, Inc., Portland, OR
Author: Stanley E. Manahan
Publisher: CRC Press
Published: 1992-03-17
Total Pages: 466
ISBN-13: 9780873716215
DOWNLOAD EBOOK →Toxicological Chemistry, 2nd Edition provides an easy-to-understand general discussion of biological processes operating on environmental chemical species. It also focuses on the chemistry of toxic substances based on their interactions with biological tissue and living organisms. The book is designed to appeal to readers with diverse general backgrounds. It assumes only a minimal background in chemistry and none in biology or microbiology. Introductory material regarding these fields is presented in the first few chapters so that more sophisticated topics can be addressed throughout the remainder of the book. Detailed discussions about specific areas of research are avoided, although key references on major topics are provided for readers who require more in-depth information. Toxicological Chemistry, 2nd Edition is useful for anyone concerned with the biological fate and effects of chemicals. It is ideal as a general reference book, source of background material, or textbook for regulatory personnel, students, engineers with consulting firms, health and safety personnel, and others.
Author: Brian J. Lukey
Publisher: CRC Press
Published: 2007-12-17
Total Pages: 752
ISBN-13: 1420046624
DOWNLOAD EBOOK →The first edition of this book, Chemical Warfare Agents: Toxicity at Low Levels, was published just prior to the terrorist attacks of September 11th, 2001. Reflecting a greater sense of urgency within the field of chemical defense since this event, research related to chemical warfare agents (CWAs) continues to expand at a remarkable pace.
Author: Donald G. Crosby
Publisher: Oxford University Press on Demand
Published: 1998
Total Pages: 336
ISBN-13: 9780195117134
DOWNLOAD EBOOK →Although they are two aspects of the same subject, environmental toxicology and environmental chemistry are usually presented as though they are entirely separate from one another; even their practitioners often seem unaware of the connections. Environmental Toxicology and Chemistry is the first text to tie these subjects closely together, demonstrating the immediate relevance of each subject to the other while also providing basic, easily understandable introductions to both areas. This unique work presents their principles and applications through numerous illustrative examples and special topics that highlight current environmental concerns. It provides up-to-date as well as historical examples of both subjects and includes discussions of ecotoxicology, epidemiology, predictive methods, and other topics not covered in similar texts. It also includes invertebrates and nonmammal vertebrates, plants, and microorganisms, as well as humans and other mammals. The first five chapters place chemicals in the environment; the following five provide the biological and toxicological settings; and the remaining six chapters offer examples of specific chemicals, their toxic effects and significance, and predictions of fate and toxicity. Each chapter concludes with a discussion of a related topic of particular public and scientific interest, such as chemical carcinogens, pesticide residues, or hazardous wastes. Ideal for advanced undergraduate and graduate students in environmental toxicology courses, Environmental Toxicology and Chemistry offers a timely, comprehensive introduction to the principles of toxicology as they apply to our environment. It is also useful for professionals and practitioners in a wide range of environmentally related fields and businesses.
Author: Barry Levine
Publisher: Amer. Assoc. for Clinical Chemistry
Published: 2003
Total Pages: 406
ISBN-13: 9781890883874
DOWNLOAD EBOOK →Author: Frank A Barile
Publisher: CRC Press
Published: 2013-04-02
Total Pages: 368
ISBN-13: 1842145282
DOWNLOAD EBOOK →Nationally, toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently, the second edition of Principles of Toxicology Testing starts with basic toxicological principles, including absorption, distribution, metabolism, and elimination of toxins, including chemicals and drugs. The book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development. As in the first edition, the book begins with an introduction into the fundamentals of toxicology (Section I) to prepare readers for the subsequent topics and continues through with a discussion of toxicokinetics and human risk assessment. This introductory material is useful in understanding the applications of toxicology testing. Section II describes the fundamental principles of toxicology testing in animals in greater detail. This section describes acute toxicity studies as well as subchronic and chronic studies performed on animals. Special emphasis is placed on study design and determination of classical indicators for acute and chronic testing, such as the LD50. The book examines other short- and long-term animal toxicity testing methodologies, including dermal, ocular, and reproductive toxicity testing. In addition, mutagenicity and carcinogenicity studies are also discussed in separate chapters. Section III introduces and discusses in vitro alternatives to animal toxicology tests. This section emphasizes cell culture methodology and cellular methods for acute systemic toxicity, target organ toxicity, and local toxicity. The contributors present the advantages and disadvantages of alternative methods. They also describe the use of high-throughput screening and its applications, the concepts of standardization and validation of in vitro techniques (especially large, organized validation efforts currently supported by US and EU regulatory agencies), and the theories supporting the development of in vitro methodologies. This second edition is a must-read for undergraduate and graduate toxicology students. Industrial and academic research centers will also find the text useful for establishing a toxicology testing laboratory.
Author: Stanley E. Manahan
Publisher: CRC Press
Published: 2000-07-31
Total Pages: 1024
ISBN-13: 9781566704915
DOWNLOAD EBOOK →Written by a leader in the field, the Fundamentals of Environmental Chemistry, Second Edition puts the fundamentals of chemistry and environmental chemistry right at your students fingertips. Manahan presents the material in an understandable and interesting manner without being overly simplistic. They get basic coverage on: - Matter and the basis of its physical nature and behavior - Organic and biological chemistry - Chemistry of water, soil, and air - Industrial chemistry - Toxicological chemistry as it pertains to occupational health and human exposure to pollutants and toxicants - Energy, nuclear energy, and nuclear waste - Applications of nuclear science in areas such as tracing pesticide degradation and nuclear medicine - More than an introduction to this field, Fundamentals of Environmental Chemistry, Second Edition provides the foundation that gives your students an understanding of the chemical processes of the environment and the effects pollution on those processes.
Author: Franz Worek
Publisher: Royal Society of Chemistry
Published: 2016-05-06
Total Pages: 346
ISBN-13: 178262807X
DOWNLOAD EBOOK →Despite ongoing efforts to prohibit the production, storage and use of chemical warfare agents recent world events highlight the enduring threat to the population from these agents. Research efforts in various countries have resulted in novel insights into chemical warfare toxicology that has enabled the development of new approaches for the diagnosis and treatment of chemical warfare poisoning. This book provides an up-to-date treatise on the diagnosis and verification of exposure, and the pre- and post-exposure treatment of poisoning. Focussing on the most important representative nerve and blistering agents, whilst also covering other potential chemical warfare agents, this book will give the reader a comprehensive overview of the many different aspects of chemical warfare agent toxicology. The text will appeal to toxicologists, biochemists and weapons specialists working in industry and academia, and anyone with an interest in chemical warfare toxicology or exposure.
Author: Stanley E. Manahan
Publisher: CRC Press
Published: 2002-09-25
Total Pages: 456
ISBN-13: 9781420032123
DOWNLOAD EBOOK →This unique book bridges the gap between toxicology and chemistry at a level understandable by a wide spectrum of readers with various interests and a broad range of backgrounds in chemistry, biochemistry, and toxicology. The third edition has been thoroughly updated and expanded to reflect recent advances in important areas of research, including toxicogenetics and toxic effects on various body systems. Toxicological Chemistry and Biochemistry, Third Edition begins by outlining the basic concepts of general chemistry, organic chemistry, and biochemistry needed to understand the topics in the book. The author then presents an overview of environmental chemistry so that you can understand the remainder of the material covered within that framework. He also discusses biodegradation, bioaccumulation, and biochemical processes that occur in water and soil. The new chapter on toxic effects considers toxicities to the endocrine and reproductive systems, and the section on xenobiotics analysis deals with the determination of toxicants and their metabolites in blood and other biological materials. The chapter on the genetic aspects of toxicology discusses the ways in which chemical damage to DNA can cause mutations, cancer, and other toxic effects on specific body systems, and it considers the role of genetics in determining individual susceptibilities to various toxicants. Toxicological Chemistry and Biochemistry, Third Edition retains the basic information and structure that made the first two editions popular with students and industry professionals, while enhancing the usefulness of the book and modernizing it in important areas. Review questions and supplementary references at the end of each chapter round out the third edition of this bestselling work.
Author: Michael J. Derelanko
Publisher: CRC Press
Published: 2001-08-29
Total Pages: 1448
ISBN-13: 9780849303708
DOWNLOAD EBOOK →LOCATE FREQUENTLY USED INFORMATION EASILY AND QUICKLY Working in the laboratory or office, you use a diverse assortment of basic information to design, conduct, and interpret toxicology studies and to perform risk assessments. The Second Edition of the best-selling Handbook of Toxicology gives you the information you need in a single reference source. NEW IN THIS EDITION: Expanded coverage of inhalation toxicology, neurotoxicology, and histopathology Additional regulatory chapters dealing with pesticides, medical devices, consumer products, and world-wide notification of new chemicals Areas of toxicology missing from the first edition such as ecotoxicology and in vitro toxicology A chapter providing extensive overview of the toxicology of metals Two chapters on basic male and female endocrinology and related toxicology Information on differences in physiological and biochemical parameters between children and adults References to Web site sources of valuable information Over 200 new tables and figures THE SINGLE SOURCE FOR THE INFORMATION YOU USE MOST FREQUENTLY Updated and expanded, this unique book includes practical reference information useful to toxicologists in the chemical and pharmaceutical industries, contract laboratories, regulatory agencies, and academia. To help you find information quickly and easily, data is arranged by toxicology subspecialty and each chapter begins with a detailed listing of information presented. Containing over 700 tables and figures, Handbook of Toxicology, Second Edition gives you a single source for the information you use most often.
