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Toxic Substances in Health Biology
Author: Edgar C. Tomlinson
Publisher:
Published: 1988-10-01
Total Pages: 150
ISBN-13: 9780881649574
DOWNLOAD EBOOK →Monitoring Human Tissues for Toxic Substances
Author: National Research Council
Publisher: National Academies Press
Published: 1991-02-01
Total Pages: 224
ISBN-13: 0309044375
DOWNLOAD EBOOK →The National Human Monitoring Program (NHMP) identifies concentrations of specific chemicals in human tissues, including toxicologic testing and risk assessment determinations. This volume evaluates the current activities of the NHMP; identifies important scientific, technical, and programmatic issues; and makes recommendations regarding the design of the program and use of its products.
Toxic Chemical and Biological Agents
Author: Giovanni Sindona
Publisher: Springer Nature
Published: 2020-10-19
Total Pages: 282
ISBN-13: 940242041X
DOWNLOAD EBOOK →This book critically assesses the current state of knowledge on new and important detection technologies, e.g. mass spectrometry, tandem mass spectrometry, biosensor detection and tissue imaging, in connection with toxic chemical and biological agents. In general, the main topics discussed concern the risks and consequences of chemical and biological agents for human health in general, with special emphasis on all biochemical and metabolic pathways including the reproductive system. The exposome, genetic risks and the environment, various health hazard agents, risk assessment, environmental assessment and preparedness, and analysis of sub-lethal effects at the molecular level are also discussed. In closing, the book provides comprehensive information on the diagnosis of exposure, and on health concerns related to toxic chemical and biological agents.
Biological Safety
Author: Dawn P. Wooley
Publisher: John Wiley & Sons
Published: 2017-02-01
Total Pages: 953
ISBN-13: 1683673131
DOWNLOAD EBOOK →Biological safety and biosecurity protocols are essential to the reputation and responsibility of every scientific institution, whether research, academic, or production. Every risk—no matter how small—must be considered, assessed, and properly mitigated. If the science isn't safe, it isn't good. Now in its fifth edition, Biological safety: Principles and Practices remains the most comprehensive biosafety reference. Led by editors Karen Byers and Dawn Wooley, a team of expert contributors have outlined the technical nuts and bolts of biosafety and biosecurity within these pages. This book presents the guiding principles of laboratory safety, including: the identification, assessment, and control of the broad variety of risks encountered in the lab; the production facility; and, the classroom. Specifically, Biological Safety covers protection and control elements—from biosafety level cabinets and personal protection systems to strategies and decontamination methods administrative concerns in biorisk management, including regulations, guidelines, and compliance various aspects of risk assessment covering bacterial pathogens, viral agents, mycotic agents, protozoa and helminths, gene transfer vectors, zooonotic agents, allergens, toxins, and molecular agents as well as decontamination, aerobiology, occupational medicine, and training A resource for biosafety professionals, instructors, and those who work with pathogenic agents in any capacity, Biological safety is also a critical reference for laboratory managers, and those responsible for managing biohazards in a range of settings, including basic and agricultural research, clinical laboratories, the vivarium, field study, insectories, and greenhouses.
Ecotoxicity and Human Health
Author: Arthur D. Bloom
Publisher: CRC Press
Published: 1995-10-09
Total Pages: 340
ISBN-13: 9781566701419
DOWNLOAD EBOOK →Ecotoxicity and Human Health emphasizes the relationships between toxicity, ecological systems, and human health. It focuses on the extent and nature of hazardous waste sites and how their effects may be studied in humans and other systems, using in vitro models, biomarkers of cellular and molecular damage, and animal models. It also includes considerable information on bioremediation, legal and regulatory issues, public perceptions and societal responses, quantitative modeling and analysis, and international directives. One of the unique features of Ecotoxicity and Human Health is its coverage of the legislative actions that have occurred over the past two decades and which have most affected the issue of hazardous waste. The book discusses the Superfund Statute, the Resource Conservation and Recovery Act (RCRA), the Toxic Substances Control Act (TSCA), the Ocean Dumping Act of 1972, the Rio Conference, United Nations Declarations, EC Regulations and Directives, and selected state legislation.
Systems Biology in Toxicology and Environmental Health
Author: Rebecca Fry
Publisher: Academic Press
Published: 2015-06-11
Total Pages: 285
ISBN-13: 0128015683
DOWNLOAD EBOOK →Systems Biology in Toxicology and Environmental Health uses a systems biological perspective to detail the most recent findings that link environmental exposures to human disease, providing an overview of molecular pathways that are essential for cellular survival after exposure to environmental toxicants, recent findings on gene-environment interactions influencing environmental agent-induced diseases, and the development of computational methods to predict susceptibility to environmental agents. Introductory chapters on molecular and cellular biology, toxicology and computational biology are included as well as an assessment of systems-based tools used to evaluate environmental health risks. Further topics include research on environmental toxicants relevant to human health and disease, various high-throughput technologies and computational methods, along with descriptions of the biological pathways associated with disease and the developmental origins of disease as they relate to environmental contaminants. Systems Biology in Toxicology and Environmental Health is an essential reference for undergraduate students, graduate students, and researchers looking for an introduction in the use of systems biology approaches to assess environmental exposures and their impacts on human health. Provides the first reference of its kind, demonstrating the application of systems biology in environmental health and toxicology Includes introductions to the diverse fields of molecular and cellular biology, toxicology, and computational biology Presents a foundation that helps users understand the connections between the environment and health effects, and the biological mechanisms that link them
Mechanistic Toxicology
Author: Urs A. Boelsterli
Publisher: CRC Press
Published: 2007-03-23
Total Pages: 424
ISBN-13: 9780849372728
DOWNLOAD EBOOK →A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology. Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible format of the original to present the general principles that link xenobiotic-induced toxicity with the molecular pathways that underlie these toxic effects. Extensively illustrated, this book forms a conceptual bridge between multiple events at the molecular level and the determinants of toxicity at the physiological and cellular level. Specific examples of drugs, environmental pollutants, and other chemicals are carefully chosen to illustrate and highlight the fundamental mechanisms of toxicity at different toxicokinetic and toxicodynamic levels. The book includes references and review articles at the end of each chapter, as well as boxed text for relevant review information on biological, biochemical, molecular, and toxicological background. Linking molecular pathways to more general biomedical contexts, the author ensures that the reader is not lost in the details and instead receives a broad understanding of the processes underlying xenobiotic toxicity. New in the Second Edition Updated chapters Types of toxic responses Disruption of signal transduction by xenobiotics Disruption of mitochondrial function Novel mechanisms derived from systems toxicology
Toxicology and Environmental Health Information Resources
Author: Institute of Medicine
Publisher: National Academies Press
Published: 1997-02-10
Total Pages: 172
ISBN-13: 0309175011
DOWNLOAD EBOOK →The environment is increasingly recognized as having a powerful effect on human and ecological health, as well as on specific types of human morbidity, mortality, and disability. While the public relies heavily on federal and state regulatory agencies for protection from exposures to hazardous substances, it often looks to health professionals for information about routes of exposure and the nature and extent of associated adverse health consequences. However, most health professionals acquire only a minimal knowledge of toxicology during their education and training. In 1967 the National Library of Medicine (NLM) created an information resource, known today as the Toxicology and Environmental Health Information Program (TEHIP). In 1995 the NLM asked the Institute of Medicine to examine the accessiblity and utility of the TEHIP databases for the work of health professionals. This resulting volume contains chapters on TEHIP and other toxicology and environmental health databases, on understanding the toxicology and environmental health information needs of health professionals, on increasing awareness of information resources through training and outreach, on accessing and navigating the TEHIP databases, and on program issues and future directions.
Essentials of Toxicology for Health Protection
Author: David Baker
Publisher: Oxford University Press
Published: 2012-03-15
Total Pages: 368
ISBN-13: 9780199652549
DOWNLOAD EBOOK →Essentials of Toxicology for Health Protection is a key handbook and course reader for all health protection professionals. It covers the basics of toxicology and its application to issues of topical concern including contaminated land, water pollution and traditional medicines.
