Premanufacture Notification

Premanufacture Notification PDF

Author: Stephen C. DeVito

Publisher: John Wiley & Sons

Published: 1997-04-11

Total Pages: 146

ISBN-13: 0471191515

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The first and only guidance document to help applicants from chemical manufacturers obtain approval to synthesize and manufacture a chemical compound. Written by two EPA scientists, it provides coverage of chemical information needed for risk assessment to satisfy the requirements of the PMN review process and comply with the Toxic Substance Control Act.

Toxicological Profile for Asbestos (Update)

Toxicological Profile for Asbestos (Update) PDF

Author: G. Douglas Hanley

Publisher: DIANE Publishing

Published: 2011

Total Pages: 441

ISBN-13: 1437930719

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This is a print on demand edition of a hard to find publication. Asbestos is a group of 6 different fibrous minerals that occur naturally in the environment. All forms of asbestos are hazardous, and all can cause cancer. This profile includes: (1) The exam¿n. and interpretation of toxicologic info. and epidemiological eval¿s. on asbestos to ascertain the levels of human exposure for the substance and its health effects; (2) A determination of whether adequate info. on the health effects of asbestos is available or in the process of development to determine levels of exposure that present a significant risk to human health; and (3) Where appropriate, identification of toxicologic testing needed to identify the types or levels of exposure that may present significant risk of adverse health effects in humans. Charts and tables.