Towards a New Paradigm for Statistical Evidence

Towards a New Paradigm for Statistical Evidence PDF

Author: Jae H. (Paul) Kim

Publisher: MDPI

Published: 2021-08-31

Total Pages: 104

ISBN-13: 3036508821

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Many scientists now widely agree that the current paradigm of statistical significance should be abandoned or largely modified. In response to these calls for change, a Special Issue of Econometrics (MDPI) has been proposed. This book is a collection of the articles that have been published in this Special Issue. These seven articles add new insights to the problem and propose new methods that lay a solid foundation for the new paradigm for statistical significance.

Towards a New Paradigm for Statistical Evidence

Towards a New Paradigm for Statistical Evidence PDF

Author: Muhammad Ishaq Bhatti

Publisher:

Published: 2021

Total Pages: 104

ISBN-13: 9783036508832

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Many scientists now widely agree that the current paradigm of statistical significance should be abandoned or largely modified. In response to these calls for change, a Special Issue of Econometrics (MDPI) has been proposed. This book is a collection of the articles that have been published in this Special Issue. These seven articles add new insights to the problem and propose new methods that lay a solid foundation for the new paradigm for statistical significance.

Statistical Evidence

Statistical Evidence PDF

Author: Richard Royall

Publisher: Routledge

Published: 2017-11-22

Total Pages: 258

ISBN-13: 1351414550

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Interpreting statistical data as evidence, Statistical Evidence: A Likelihood Paradigm focuses on the law of likelihood, fundamental to solving many of the problems associated with interpreting data in this way. Statistics has long neglected this principle, resulting in a seriously defective methodology. This book redresses the balance, explaining why science has clung to a defective methodology despite its well-known defects. After examining the strengths and weaknesses of the work of Neyman and Pearson and the Fisher paradigm, the author proposes an alternative paradigm which provides, in the law of likelihood, the explicit concept of evidence missing from the other paradigms. At the same time, this new paradigm retains the elements of objective measurement and control of the frequency of misleading results, features which made the old paradigms so important to science. The likelihood paradigm leads to statistical methods that have a compelling rationale and an elegant simplicity, no longer forcing the reader to choose between frequentist and Bayesian statistics.

Model Based Inference in the Life Sciences

Model Based Inference in the Life Sciences PDF

Author: David R. Anderson

Publisher: Springer Science & Business Media

Published: 2007-12-22

Total Pages: 203

ISBN-13: 0387740759

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This textbook introduces a science philosophy called "information theoretic" based on Kullback-Leibler information theory. It focuses on a science philosophy based on "multiple working hypotheses" and statistical models to represent them. The text is written for people new to the information-theoretic approaches to statistical inference, whether graduate students, post-docs, or professionals. Readers are however expected to have a background in general statistical principles, regression analysis, and some exposure to likelihood methods. This is not an elementary text as it assumes reasonable competence in modeling and parameter estimation.

Federal Statistics, Multiple Data Sources, and Privacy Protection

Federal Statistics, Multiple Data Sources, and Privacy Protection PDF

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2018-01-27

Total Pages: 195

ISBN-13: 0309465370

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The environment for obtaining information and providing statistical data for policy makers and the public has changed significantly in the past decade, raising questions about the fundamental survey paradigm that underlies federal statistics. New data sources provide opportunities to develop a new paradigm that can improve timeliness, geographic or subpopulation detail, and statistical efficiency. It also has the potential to reduce the costs of producing federal statistics. The panel's first report described federal statistical agencies' current paradigm, which relies heavily on sample surveys for producing national statistics, and challenges agencies are facing; the legal frameworks and mechanisms for protecting the privacy and confidentiality of statistical data and for providing researchers access to data, and challenges to those frameworks and mechanisms; and statistical agencies access to alternative sources of data. The panel recommended a new approach for federal statistical programs that would combine diverse data sources from government and private sector sources and the creation of a new entity that would provide the foundational elements needed for this new approach, including legal authority to access data and protect privacy. This second of the panel's two reports builds on the analysis, conclusions, and recommendations in the first one. This report assesses alternative methods for implementing a new approach that would combine diverse data sources from government and private sector sources, including describing statistical models for combining data from multiple sources; examining statistical and computer science approaches that foster privacy protections; evaluating frameworks for assessing the quality and utility of alternative data sources; and various models for implementing the recommended new entity. Together, the two reports offer ideas and recommendations to help federal statistical agencies examine and evaluate data from alternative sources and then combine them as appropriate to provide the country with more timely, actionable, and useful information for policy makers, businesses, and individuals.

Pan-cancer Integrative Molecular Portrait Towards a New Paradigm in Precision Medicine

Pan-cancer Integrative Molecular Portrait Towards a New Paradigm in Precision Medicine PDF

Author: Christophe Le Tourneau

Publisher: Springer

Published: 2015-08-27

Total Pages: 144

ISBN-13: 3319221892

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This original book provides readers with an overview of the latest developments in personalized medicine clinical trials in oncology. The topics covered range from the rationale behind this new generation of clinical trials and the latest statistical models for high-throughput molecular techniques, bioinformatics, high-throughput screening molecular techniques and the challenges entailed by implementing them in daily practice. It also covers the key role of pathology in the validation of molecular results and the complex assessment of predictive biomarkers. The different topics covered are supplemented by unique concrete examples based on the SHIVA trial. The authors are all members of the French Curie Institute, one of the world’s foremost cancer research institutions.

Apprenticeship: Towards a New Paradigm of Learning

Apprenticeship: Towards a New Paradigm of Learning PDF

Author: Patrick Ainley

Publisher: Routledge

Published: 2014-05-12

Total Pages: 225

ISBN-13: 1135370303

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In the light of changes the government has launched as part of its welfare to work initiatives, this text explores apprenticeship. The authors set the historical context and discuss the theoretical and practical aspects of acquiring the necessary knowledge and skills for competence.

Essays on Consciousness: Towards a New Paradigm

Essays on Consciousness: Towards a New Paradigm PDF

Author: Ingrid Fredriksson

Publisher: Balboa Press

Published: 2018-10-25

Total Pages: 342

ISBN-13: 1982208120

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Essays on Consciousness: Towards a New Paradigm is Ingrid Fredriksson ́s third book on consciousness and includzes famous coauthors from all over the world—Deepak Chopra ́s coauthor Menas C. Kafatos on The Mysteries of Consciousness, as well as Elizabeth A. Raucher, Russell Targ, and Dr. Amit Goswami, to name a few. Olle Johansson, PhD (Sweden), writes in this book about understanding adverse health effects of artificial electromagnetic fields. Is rocket science needed or just common sense? This is a very important question these days. Eve Isham will talk on “Save Free Will from Science,” and Rupert Sheldrake, PhD (England), will talk on “The Extended Mind.” “Millennial Science,” “The Imminent Age of Discovery’s Conscious Technologies” is Richard L. Amoro ́s. These are interesting chapters in this book. Carl Johan Calleman, PhD (Mexico), writes about “The Origin and History of the Human Mind,” and Attila Grandpierre, PhD (Hungary), writes “All Is One: The One, the Universe, and Consciousness.” Gerard J. F. Blommestijn, PhD (Netherlands), has “A Theory on the Relation between Quantum Mechanical Reduction Process and Consciousness.” “Direct Experience: The Open Door to Realize Limitless Consciousness” is Klaus Stüben’s, PhD (Germany), interesting chapter. Anita Westlund has “Finding of a Big Chakra Involving the Cheops Pyramid of Giza.” It is built on the Fibonacci series of holy numbers. It is a circle quadrature in the very soil matter of the globe. “Music and Consciousness” is Alexander Graur ́s fabulous chapter, and “Can Consciousness Influence Our Epigenetics and Can Epigenetic Influence Our Consciousness” is Ingrid Fredriksson ́s part on our day’s new paradigm. The book is fascinating, highly educational, and informative—a must-have!