Towards 4D Bioprinting

Towards 4D Bioprinting PDF

Author: Adrian Neagu

Publisher: Academic Press

Published: 2022-11-17

Total Pages: 302

ISBN-13: 012818745X

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Towards 4D Printing presents the current state of three-dimensional (3D) bioprinting and its recent offspring, 4D bioprinting. These are attractive approaches to tissue engineering because they hold the promise of building bulky tissue constructs with incorporated vasculature. Starting with the discussion of 3D and 4D printing of inanimate objects, the book presents several 3D bioprinting techniques and points out the challenges imposed by living cells on the bioprinting process. It argues that, in order to fine-tune the bioprinter, one needs a quantitative analysis of the conditions experienced by cells during printing. Once the printing is over, the construct evolves according to mechanisms known from developmental biology. These are described in the book along with computer simulations that aim to predict the outcome of 3D bioprinting.In addition, the book provides the latest information on the principles and applications of 4D bioprinting, such as for medical devices and assistive technology. The last chapter discusses the perspectives of the field. This book provides an up-to date description of the theoretical tools developed for the optimization of 3D bioprinting, presents the morphogenetic mechanisms responsible for the post-printing evolution of the bioprinted construct and describing computational methods for simulating this evolution, and discusses the leap from 3D to 4D bioprinting in the light of the latest developments in the field. Most importantly, Towards 4D Printing explains the importance of theoretical modeling for the progress of 3D and 4D bioprinting. Presents theoretical tools needed for the optimization of the bioprinting process Describes the principles and implementation of computer simulations needed to predict the outcome of 3D bioprinting Analyzes the distinctive features of 4D bioprinting along with its applications and perspectives

3D and 4D Printing in Biomedical Applications

3D and 4D Printing in Biomedical Applications PDF

Author: Mohammed Maniruzzaman

Publisher: John Wiley & Sons

Published: 2019-03-18

Total Pages: 490

ISBN-13: 3527344438

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Ein professioneller Leitfaden zu 3D- und 4D-Drucktechniken in der Biomedizin und Pharmazie. 3D and 4D Printing in Biomedical Applications führt fundiert in 3D- und 4D-Drucktechniken in der Biomedizin und Pharmazie ein. Dieses Fachbuch enthält Beiträge von internationalen Wissenschaftlern und Industrieexperten und bietet einen Überblick über das Thema, aktuelle Forschungsergebnisse und Innovationen zu Anwendungen in der Pharmazie und Biomedizin. Untersucht werden Prozessoptimierung, Innovationsprozesse, Engineering- und Plattformtechnologien. Darüber hinaus informiert das Werk über Entwicklungen in der Biomedizin, u. a. über Formgedächtnispolymere, Biofabrikation in 4D und Knochen aus dem Drucker. Eine Fülle von Themen werden behandelt und näher beleuchtet: Potenzial des 3D-Drucks für die Wirkstoffverabreichung, neue Fertigungsprozess, Bio-Scaffolding, neueste Trends und Herausforderungen für 3D- und 4D-Bioprinting in der Biofabrikation. Dieses wertvolle Referenzwerk - ist ein umfassender Leitfaden zu 3D- und 4D-Drucktechniken in der Biomedizin und Pharmazie. - informiert u. a. über die erste 3D-Druckplattform mit FDA-Zulassung für ein pharmazeutisches Erzeugnis. - enthält Reviews der derzeit verfügbaren pharmazeutischen Erzeugnisse, die per 3D-Druck hergestellt wurden. - präsentiert die jüngsten Fortschritte bei neuartigen Materialien für den 3D- und 4D-Druck und biomedizinische Anwendungen.

Polymer-Based Additive Manufacturing

Polymer-Based Additive Manufacturing PDF

Author: Declan M. Devine

Publisher: Springer Nature

Published: 2019-09-16

Total Pages: 277

ISBN-13: 3030245322

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This book aims to give readers a basic understanding of commonly used additive manufacturing techniques as well as the tools to fully utilise the strengths of additive manufacturing through the modelling and design phase all the way through to post processing. Guidelines for 3D-printed biomedical implants are also provided. Current biomedical applications of 3D printing are discussed, including indirect applications in the rapid manufacture of prototype tooling and direct applications in the orthopaedics, cardiovascular, drug delivery, ear-nose-throat, and tissue engineering fields. Polymer-Based Additive Manufacturing: Biomedical Applications is an ideal resource for students, researchers, and those working in industry seeking to better understand the medical applications of additive manufacturing.

Bone Tissue Engineering

Bone Tissue Engineering PDF

Author: Jeffrey O. Hollinger

Publisher: CRC Press

Published: 2004-10-14

Total Pages: 500

ISBN-13: 1135501912

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Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t

From Additive Manufacturing to 3D/4D Printing

From Additive Manufacturing to 3D/4D Printing PDF

Author: Jean-Claude André

Publisher: John Wiley & Sons

Published: 2017-12-27

Total Pages: 468

ISBN-13: 1119482763

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With a turnover of some 5-15 billion € / year, the additive manufacturing has industrial niches bearers thanks to processes and materials more and more optimized. While some niches still exist on the application of additive techniques in traditional fields (from jewelery to food for example), several trends emerge, using new concepts: collective production, realization of objects at once (without addition Of material), micro-fluidic, 4D printing exploiting programmable materials and materials, bio-printing, etc. There are both opportunities for new markets, promises not envisaged less than 10 years ago, but difficulties in reaching them.

3D Bioprinting in Regenerative Engineering

3D Bioprinting in Regenerative Engineering PDF

Author: Ali Khademhosseini

Publisher: CRC Press

Published: 2018-04-17

Total Pages: 300

ISBN-13: 1315280477

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Regenerative engineering is the convergence of developmental biology, stem cell science and engineering, materials science, and clinical translation to provide tissue patches or constructs for diseased or damaged organs. Various methods have been introduced to create tissue constructs with clinically relevant dimensions. Among such methods, 3D bioprinting provides the versatility, speed and control over location and dimensions of the deposited structures. Three-dimensional bioprinting has leveraged the momentum in printing and tissue engineering technologies and has emerged as a versatile method of fabricating tissue blocks and patches. The flexibility of the system lies in the fact that numerous biomaterials encapsulated with living cells can be printed. This book contains an extensive collection of papers by world-renowned experts in 3D bioprinting. In addition to providing entry-level knowledge about bioprinting, the authors delve into the latest advances in this technology. Furthermore, details are included about the different technologies used in bioprinting. In addition to the equipment for bioprinting, the book also describes the different biomaterials and cells used in these approaches. This text: Presents the principles and applications of bioprinting Discusses bioinks for 3D printing Explores applications of extrusion bioprinting, including past, present, and future challenges Includes discussion on 4D Bioprinting in terms of mechanisms and applications

3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine

3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine PDF

Author: Lijie Grace Zhang

Publisher: Academic Press

Published: 2022-02-18

Total Pages: 563

ISBN-13: 0128245530

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3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine, Second Edition provides an in-depth introduction to bioprinting and nanotechnology and their industrial applications. Sections cover 4D Printing Smart Multi-responsive Structure, Cells for Bioprinting, 4D Printing Biomaterials, 3D/4D printing functional biomedical devices, 3D Printing for Cardiac and Heart Regeneration, Integrating 3D printing with Ultrasound for Musculoskeletal Regeneration, 3D Printing for Liver Regeneration, 3D Printing for Cancer Studies, 4D Printing Soft Bio-robots, Clinical Translation and Future Directions. The book's team of expert contributors have pooled their expertise in order to provide a summary of the suitability, sustainability and limitations of each technique for each specific application. The increasing availability and decreasing costs of nanotechnologies and 3D printing technologies are driving their use to meet medical needs. This book provides an overview of these technologies and their integration. Includes clinical applications, regulatory hurdles, and a risk-benefit analysis of each technology Assists readers in selecting the best materials and how to identify the right parameters for printing Includes the advantages of integrating 3D printing and nanotechnology in order to improve the safety of nano-scale materials for biomedical applications

Bioresorbable Polymers

Bioresorbable Polymers PDF

Author: Declan Devine

Publisher: Walter de Gruyter GmbH & Co KG

Published: 2019-04-15

Total Pages: 241

ISBN-13: 311064066X

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Bioresorbable implants can be processed via conventional polymer processing methods such as extrusion, injection and compressing moulding, solvent spinning or casting. This book addresses issues and highlights recent advances in the use of biodegradable polymers. It is intended for researchers utilizing biodegradable polymers in areas from tissue engineering to controlled release of active pharmaceuticals, as well as industrial processors.

3D Bioprinting in Regenerative Engineering

3D Bioprinting in Regenerative Engineering PDF

Author: Ali Khademhosseini

Publisher: CRC Press

Published: 2018-04-17

Total Pages: 385

ISBN-13: 1315280485

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Regenerative engineering is the convergence of developmental biology, stem cell science and engineering, materials science, and clinical translation to provide tissue patches or constructs for diseased or damaged organs. Various methods have been introduced to create tissue constructs with clinically relevant dimensions. Among such methods, 3D bioprinting provides the versatility, speed and control over location and dimensions of the deposited structures. Three-dimensional bioprinting has leveraged the momentum in printing and tissue engineering technologies and has emerged as a versatile method of fabricating tissue blocks and patches. The flexibility of the system lies in the fact that numerous biomaterials encapsulated with living cells can be printed. This book contains an extensive collection of papers by world-renowned experts in 3D bioprinting. In addition to providing entry-level knowledge about bioprinting, the authors delve into the latest advances in this technology. Furthermore, details are included about the different technologies used in bioprinting. In addition to the equipment for bioprinting, the book also describes the different biomaterials and cells used in these approaches. This text: Presents the principles and applications of bioprinting Discusses bioinks for 3D printing Explores applications of extrusion bioprinting, including past, present, and future challenges Includes discussion on 4D Bioprinting in terms of mechanisms and applications

Smart Materials in Additive Manufacturing, volume 1: 4D Printing Principles and Fabrication

Smart Materials in Additive Manufacturing, volume 1: 4D Printing Principles and Fabrication PDF

Author: Mahdi Bodaghi

Publisher: Elsevier

Published: 2022-06-25

Total Pages: 484

ISBN-13: 0128240830

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Smart Materials in Additive Manufacturing, Volume 1 provides readers with an overview of the current smart materials widely in use and the techniques for additively manufacturing them. It demonstrates the principles developed for 4D printing in a way that is useful for students, early career researchers, and professionals. Topics covered include modeling and fabrication of 4D printed materials such as dielectric elastomer soft robots, low-voltage electroactive polymers, and stimuli-responsive hydrogels. 4D printing of light-responsive structures, gels and soft materials, and natural fiber composites are also discussed, as is origami-inspired 4D printing, 4D microprinting, and reversible 4D printing. 4D bioprinting and related biomedical applications are outlined as well as functionalized 4D printed sensor systems. Key Features:* Discusses 4D printed shape memory polymers, shape memory alloys, natural fibers, and hydrogels* Covers various types of stimuli, fabrication techniques, multi-physics modeling, and control strategies for 4D printing* Explores 4D printing of dielectric elastomers, liquid crystal elastomers, and electroactive polymers Covers the mechanics, manufacturing processes and applications of 4D-printed smart materials and structures Discusses applications in civil, mechanical, aerospace, polymer and biomedical engineering Presents experimental, numerical and analytical studies in a simple and straightforward manner, providing tools that can be immediately implemented and adapted by readers to fit their work