Thrombosis and Hemostasis in Cancer

Thrombosis and Hemostasis in Cancer PDF

Author: Gerald Soff

Publisher:

Published: 2019

Total Pages:

ISBN-13: 9783030203160

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In this book, leaders in the field explore our current understanding of thrombosis and hemostasis in cancer and address key questions on the subject. Among the topics discussed are the mechanisms that cancers use to activate the coagulation system, and those by means of which an activated coagulation system can lead to more aggressive cancer growth. Clinical chapters examine the role of thrombosis prophylaxis and treatment, central line-associated thrombosis, and cancer-associated hemorrhage. Subsequent chapters deal with the management of chemotherapy-induced thrombocytopenia, anticoagulation in the presence of brain metastases, and other unique challenges in the interaction of thrombosis and hemostasis in cancer. It has been 150 years since Armand Trousseau first described the well-known association between cancer and an increased risk of thrombosis, which may be considered the first paraneoplastic syndrome ever identified. More recently, numerous studies have indicated that activation of the coagulation system by cancer not only increases the likelihood of thrombosis, but is also associated with a more aggressive cancer phenotype. By familiarizing readers with the latest developments in this complex and challenging field, the book offers a valuable resource for scientists and clinicians alike.

Thrombosis and Hemostasis in Cancer

Thrombosis and Hemostasis in Cancer PDF

Author: Gerald Soff

Publisher: Springer

Published: 2019-07-17

Total Pages: 203

ISBN-13: 3030203158

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In this book, leaders in the field explore our current understanding of thrombosis and hemostasis in cancer and address key questions on the subject. Among the topics discussed are the mechanisms that cancers use to activate the coagulation system, and those by means of which an activated coagulation system can lead to more aggressive cancer growth. Clinical chapters examine the role of thrombosis prophylaxis and treatment, central line-associated thrombosis, and cancer-associated hemorrhage. Subsequent chapters deal with the management of chemotherapy-induced thrombocytopenia, anticoagulation in the presence of brain metastases, and other unique challenges in the interaction of thrombosis and hemostasis in cancer. It has been 150 years since Armand Trousseau first described the well-known association between cancer and an increased risk of thrombosis, which may be considered the first paraneoplastic syndrome ever identified. More recently, numerous studies have indicated that activation of the coagulation system by cancer not only increases the likelihood of thrombosis, but is also associated with a more aggressive cancer phenotype. By familiarizing readers with the latest developments in this complex and challenging field, the book offers a valuable resource for scientists and clinicians alike.

Cancer-Associated Thrombosis

Cancer-Associated Thrombosis PDF

Author: Alok A. Khorana

Publisher: CRC Press

Published: 2007-09-26

Total Pages: 290

ISBN-13: 1420048007

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Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides

Thrombosis and Cancer

Thrombosis and Cancer PDF

Author: Gilles Lugassy

Publisher: CRC Press

Published: 2004-02-23

Total Pages: 256

ISBN-13: 9781841842875

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It is common knowledge that thromboembolic disease is often the earliest manifestation and almost the most frequent complication of cancer. Recent studies have investigated the mechanisms by which cancer causes thrombosis and have emphasized the importance of the coagulation system in angiogenesis and tumor metastasis. Thrombosis and Cancer offers a detailed and authoritative review of the issues involved in the links between thrombosis, hemostasis, and cancer, an association long documented but still not completely understood. This text provides comprehensive and timely coverage of the current knowledge of cancer-associated thrombosis, its pathogenesis, clinical features, prevention, and therapy. It specifically addresses the relationship between hemostatic systems and cancer, thus providing a unique and much needed focus. All of the contributors are acknowledged specialists in their fields and have experience conducting large clinical trials in oncology and thrombosis. Their discussions cover all aspects of the topic, from long-term complications to cancer surgery. With input from specialists in a range of disciplines including hematology, pharmacology, and surgery, this thorough text will be of interest to general practitioners, internists, oncologists, hematologists, and all physicians involved in the management of cancer patients.

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