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Therapy Approaches in Neurological Disorders

Author: Mario Bernardo-Filho

Publisher: BoD – Books on Demand

Published: 2021-07-14

Total Pages: 168

ISBN-13: 1839686685

Neurological disorders are conditions affecting the central or peripheral nervous system, with undesirable consequences for the quality of life. This book highlights and discusses several approaches for managing these conditions and improving the functional capacity and quality of life of patients, including whole-body vibration exercise, biofeedback, sagittal plane spine alignment, allopathic and non-allopathic medications, phytotherapy, and more.

Gene Therapy for Neurological Disorders

Author: Fredric P. Manfredsson

Publisher: Humana

Published: 2015-11-26

Total Pages: 0

ISBN-13: 9781493932702

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This volume provides a clear and detailed roadmap of how to design and execute a gene therapy experiment in order to obtain consistent results. Chapters in this book disseminate bits of unknown information that are important to consider during the course of experimentation and will answer questions such as: What delivery vehicle do you use?; How will you ensure that your vector retains stability?; What expression system best fits your needs?; What route will you choose to deliver your gene therapy agent?; How will you model the neurodegenerative disorder that you aim to investigate and what are the proven methods to treat these disorders in preclinical models? Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Gene Therapy for Neurological Disorders: Methods and Protocols, is a compilation of protocols and instructive chapters intended to give researchers, clinicians, and students of all levels, a foundation upon which future gene therapy experiments can be designed.

Handbook of Neurological Therapy

Author: Carlo Colosimo

Publisher: Oxford University Press, USA

Published: 2015

Total Pages: 481

ISBN-13: 0199862923

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This is a practical book on neurological therapy. It is aimed at giving concise and updated answers to busy practicing clinicians in the clinic, ward, or emergency department. An evidence-based approach is used, but when there is no evidence or the data are inconclusive, an expert opinion is always given in order to meet the expectations of the reader. All neurological conditions, common and less common, are discussed; each chapter has a similar format, and contains an initial brief introduction on the epidemiology and clinical features of each disease. The therapy is then discussed, including pharmacological and non-pharmacological, with wide use of Tables & Figures. Flowcharts are also included in most of the chapters.

Developing Multimodal Therapies for Brain Disorders

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2017-03-13

Total Pages: 97

ISBN-13: 0309450268

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Multimodal therapy approaches that combine interventions aimed at different aspects of disease are emerging as potentialâ€"and perhaps essentialâ€"ways to enhance clinical outcomes for patients with psychiatric and neurological disorders. In order to examine the general principles underlying multimodal therapies and to explore challenges, potential barriers, and opportunities for their development, the National Academies of Sciences, Engineering, and Medicine convened a workshop in June 2016. Participants explored scientific, clinical, regulatory, and reimbursement issues related to multimodal approaches and potential opportunities to enhance clinical outcomes for individuals with nervous system disorders. This publication summarizes the presentations and discussions from the workshop.

Gene Therapy in Neurological Disorders

Author: Mingjie Li

Publisher: Academic Press

Published: 2018-05-25

Total Pages: 450

ISBN-13: 012809821X

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Gene therapy has tremendous potential for the treatment of neurological disorders. There has been substantial progress in the development of gene therapy strategies for neurological disorders over the last two decades. Gene Therapy in Neurological Disorders thoroughly reviews currently available gene therapy tools and presents examples of their application in a variety of neurological diseases. The book begins with general reviews of gene therapy strategies with a focus on neurological disorders. The remainder of the chapters present approaches to specific neurological disorders. Each chapter gives an in-depth introduction to the relevant field before diving into the specific tool or application. The book aims to help investigators, students and research staff better understand the principles of gene therapy and its application in the nervous system. Provides background information and experimental details of gene therapy tools applied for neuroscience research and neurological disorders Covers a broad range of gene delivery and regulation tools, therapeutic agents, and target cells, including emerging new technologies such as CRISPR/Cas9 genome editing Discusses applications of gene therapy tools to neurological disorders including neurodegeneration, muscular dystrophy, trauma and chronic pain, and neoplastic diseases

The Right Therapy for Neurological Disorders

Author: E. Beghi

Publisher: Karger Medical and Scientific Publishers

Published: 2016-07-26

Total Pages: 168

ISBN-13: 3318058653

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Most neurological disorders are chronic and aging-related. With the increase of life expectancy their incidence and prevalence will grow in the decades to come, which in turn will increase the load on medical and social systems worldwide. There is thus a desperate need for successful preventive and therapeutic measures based on randomized clinical trials (RTCs) conducted by independent organizations. This book provides a compendium relating most of the principles of reliable RTCs to specific neurological diseases. Contributed by specialized neurologists, the articles touch on important aspects of RCTs with a clear critical approach, highlighting their limitations as well as giving recommendations for their planning and conducting to address the variable genotypic and phenotypic aspects of neurological conditions. Consideration is also given to combining the clinical impact of the study results with patients’ values and the interests of pharmaceutical companies. Neurologists involved in clinical trials will certainly benefit from this book, which should become a basic text for all neurological courses dealing with evidence-based neurology.

Handbook of Decision Support Systems for Neurological Disorders

Author: Hemanth D. Jude

Publisher: Academic Press

Published: 2021-03-30

Total Pages: 320

ISBN-13: 0128222727

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Handbook of Decision Support Systems for Neurological Disorders provides readers with complete coverage of advanced computer-aided diagnosis systems for neurological disorders. While computer-aided decision support systems for different medical imaging modalities are available, this is the first book to solely concentrate on decision support systems for neurological disorders. Due to the increase in the prevalence of diseases such as Alzheimer, Parkinson’s and Dementia, this book will have significant importance in the medical field. Topics discussed include recent computational approaches, different types of neurological disorders, deep convolution neural networks, generative adversarial networks, auto encoders, recurrent neural networks, and modified/hybrid artificial neural networks. Includes applications of computer intelligence and decision support systems for the diagnosis and analysis of a variety of neurological disorders Presents in-depth, technical coverage of computer-aided systems for tumor image classification, Alzheimer’s disease detection, dementia detection using deep belief neural networks, and morphological approaches for stroke detection Covers disease diagnosis for cerebral palsy using auto-encoder approaches, contrast enhancement for performance enhanced diagnosis systems, autism detection using fuzzy logic systems, and autism detection using generative adversarial networks Written by engineers to help engineers, computer scientists, researchers and clinicians understand the technology and applications of decision support systems for neurological disorders

Translational Neuroscience

Author: Mark H. Tuszynski

Publisher: Springer

Published: 2018-04-08

Total Pages: 584

ISBN-13: 9781493979424

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Translational Neuroscience offers a far-reaching and insightful series of perspectives on the effort to bring potentially revolutionary new classes of therapies to the clinic, thereby transforming the treatment of human nervous system disorders. Great advances in the fields of basic neuroscience, molecular biology, genomics, gene therapy, cell therapy, stem cell biology, information technology, neuro devices, rehabilitation and others over the last 20 years have generated unprecedented opportunities to treat heretofore untreatable disorders of the nervous system. This book provides a wide-ranging yet detailed sample of many of these efforts, together with the methods for pursuing clinical translation and assessing clinical outcomes. Among the topics covered are Alzheimer’s disease, Parkinson’s disease, stroke, multiple sclerosis, epilepsy, motor neuron disease, pain, inborn errors of metabolism, brain tumors, spinal cord injury, neuroprosthetics, rehabilitation and clinical trial design/consideration. Translational Neuroscience is aimed at basic neuroscientists, translational neuroscientists and clinicians who seek to gain a perspective on the nature and promise of translational therapies in the current era. Both students and established professionals will benefit from the content.

Overcoming Functional Neurological Symptoms: A Five Areas Approach

Author: Christopher Williams

Publisher: CRC Press

Published: 2011-08-26

Total Pages: 320

ISBN-13: 1444138359

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Overcoming Functional Neurological Symptoms uses the proven and trusted five areas model of Cognitive Behaviour Therapy (CBT) to help people experiencing a range of medically unexplained symptoms, including chronic headaches, fatigue, dizziness, loss of sensation, weakness and numbness. Easy to use and practical, this CBT workbook: Presents the insights of award-winning authors who are experts in the field Contains therapeutic advice proven to work through years of research and practice Ensures patients success through specific plans leading to positive results Provides advice for friends and family of patients This book is designed for CBT practitioners, psychiatrists, psychologists, neurologists, physiotherapists, occupational therapists and healthcare workers to share with their patients. A linked and completely free online support course is located at www.livinglifetothefull.com with additional resources at www.fiveareas.com

Physical Management in Neurological Rehabilitation

Author: Maria Stokes

Publisher: Elsevier Health Sciences

Published: 2004

Total Pages: 572

ISBN-13: 0723432856

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Providing an introduction to the basic concepts of neurology, neurological conditions the differing methods of physiotherapy, this text brings together contributions from an experienced team of experts in the field.