Therapeutic Strategies for Modulating the Inflammatory Diseases

Therapeutic Strategies for Modulating the Inflammatory Diseases PDF

Author: B.M. Weichman

Publisher: Springer Science & Business Media

Published: 1997-11-18

Total Pages: 124

ISBN-13: 9783764356903

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The Eighth International Conference of the Inflammation Research Association was held on October 27 to 31, 1996 at Hershey Lodge and Convention Center in Hershey, Pennsylvania. As have others in this series, the conference focused on understanding the molecular mechanisms involved in acute and chronic inflammatory reactions as well as on therapeutic approaches to treating inflammatory diseases. One outstanding symposium focused on new drugs and was de signed as a forum for the dissemination of early clinical results on new anti-inflammatory agents. Other symposia spotlighted exciting advances being made in defining intracellular signaling path ways and the potential for future therapeutics that target cytokines and costimulatory pathways. This conference was characterized by a high level of participation by attendees, who represent both the academic and industrial sectors. It was gratifying to note that a large proportion of the attending scientists presented their latest findings during workshops, poster discussions, and pos ter se.ssions. This volume covers many of the highlights of the Eighth International Conference and should become a valuable resource for scientists involved in inflammation research and drug discovery.

Treating Infectious Diseases in a Microbial World

Treating Infectious Diseases in a Microbial World PDF

Author: National Research Council

Publisher: National Academies Press

Published: 2006-01-03

Total Pages: 102

ISBN-13: 0309180686

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Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.

Recent Developments in Anti-Inflammatory Therapy

Recent Developments in Anti-Inflammatory Therapy PDF

Author: Parteek Prasher

Publisher: Academic Press

Published: 2023-02-17

Total Pages: 414

ISBN-13: 0323914160

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Advances in Anti-inflammatory Therapy explores the cutting-edge in anti-inflammation therapy in clear and concise language, with insights from academia and industry. Sections cover key regulatory pathways that mediate acute and chronic inflammation and disease onset. Further chapters are devoted to advanced anti-inflammatory pharmaceuticals, including chemical moieties, pharmacophores, APIs, natural products, herbal therapies, molecular nanomedicine and advanced drug delivery vectors. Systematically planned chapters and illustrations enable potential readers to gain essential insights on the most recent advancements in the field. Arranged with systematic chapters covering a broad range of inflammatory diseases, discussions on past, current and future therapeutics and advanced anti-inflammatory pharmaceuticals, this book will be useful to a wide range of researchers, especially medicinal chemists, drug design experts, and biological and translational researchers working in the field of inflammation. Identifies recent developments and current trends in anti-inflammation therapy Discusses advanced chemotherapeutics, SAR analysis of novel pharmacophores and natural products Outlines the pathophysiology of inflammatory pathways in the pathogenesis of disease onset, including strategies to counter these intricacies Contains a blend of editors from both academia and industry

Inflammation and Cancer

Inflammation and Cancer PDF

Author: Bharat B. Aggarwal

Publisher: Springer

Published: 2014-05-12

Total Pages: 489

ISBN-13: 3034808372

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This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.

Current Advances for Development of Functional Foods Modulating Inflammation and Oxidative Stress

Current Advances for Development of Functional Foods Modulating Inflammation and Oxidative Stress PDF

Author: Blanca Hernandez-Ledesma

Publisher: Academic Press

Published: 2021-12-03

Total Pages: 676

ISBN-13: 012822584X

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Current Advances for Development of Functional Foods Modulating Inflammation and Oxidative Stress presents the nutritional and technological aspects related to the development of functional foods with anti-inflammatory and antioxidant effects. Specifically, analytical approaches for the characterization of anti-inflammatory and antioxidant properties of healthy foods and functional constituents, as well as technological strategies for the extraction of compounds and fractions from raw materials to produce anti-inflammatory and antioxidant ingredients are addressed. In addition, the molecular mechanisms by which foods and their components can modulate inflammation and their oxidative stress effects on disease prevention are explored. Finally, clinical research addressing nutritional needs in pathological subjects with inflammatory diseases are considered. Covers methods of analysis and extraction of anti-inflammatory and antioxidant compounds Offers an overview of the main anti-inflammatory and antioxidant compounds in foods Provides a guide on the mechanisms of action and health benefits of anti-inflammatory and antioxidant dietary bioactives

Cytokine Inhibitors

Cytokine Inhibitors PDF

Author: Gennaro Ciliberto

Publisher: CRC Press

Published: 2000-11-14

Total Pages: 392

ISBN-13: 9780203904244

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Compiling an up-to-date and detailed survey of the role cytokines play in cell-to-cell communication, development, and differentiation, this comprehensive reference highlights the medical advantages of cytokine inhibition and pursues novel methods of discovery for more potent and specific blocking agents. Investigates the pathogenic role of

Immune Response Activation and Immunomodulation

Immune Response Activation and Immunomodulation PDF

Author: Rajeev Tyagi

Publisher: BoD – Books on Demand

Published: 2019-04-17

Total Pages: 180

ISBN-13: 1789851513

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Immune Response Activation and Immunomodulation has been written to address the perceived needs of both medical school and undergraduate curricula and to take advantage of new understandings in immunology. We have tried to achieve several goals and present the most important principles governing the function of the immune system. Our fundamental objective has been to synthesize the key concepts from the vast amount of experimental data that have emerged in the rapidly advancing field of immunology. The choice of what is most important is based on what is most clearly established by experimentation, what our students find puzzling, and what explains the wonderful efficiency and economy of the immune system. Inevitably, however, such a choice will have an element of bias, and our bias is toward emphasizing the cellular interactions in immune response by limiting the description of many of the underlying biochemical and molecular mechanisms to the essential facts. This book gives an insight into the role of cytokines in activating immune response during pathogenic invasion. Immunomodulation, aryl hydrocarbons, the role of the protein defensin and nucleated cells in provoking immune response, Bcl protein/gene-based apoptotic pathways, and plant-derived phytochemical-mediated immune response are all central themes of this book.

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