Theory of Cortical Plasticity

Theory of Cortical Plasticity PDF

Author: Leon N. Cooper

Publisher: World Scientific

Published: 2004

Total Pages: 336

ISBN-13: 9789812387912

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This invaluable book presents a theory of cortical plasticity and shows how this theory leads to experiments that test both its assumptions and consequences. It elucidates, in a manner that is accessible to students as well as researchers, the role which the BCM theory has played in guiding research and suggesting experiments that have led to our present understanding of the mechanisms underlying cortical plasticity. Most of the connections between theory and experiment that are discussed require complex simulations. A unique feature of the book is the accompanying software package, Plasticity. This is provided complete with source code, and enables the reader to repeat any of the simulations quoted in the book as well as to vary either parameters or assumptions. Plasticity is thus a research and an educational tool. Readers can use it to obtain hands-on knowledge of the structure of BCM and various other learning algorithms. They can check and replicate our results as well as test algorithms andrefinements of their own.

Toward a Theory of Neuroplasticity

Toward a Theory of Neuroplasticity PDF

Author: Christopher A. Shaw

Publisher: Psychology Press

Published: 2013-03-07

Total Pages: 500

ISBN-13: 1134949413

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This book provides a broad survey of many of the major areas in neuroplasticity research by leading investigators in the field. The topics considered range across all levels of nervous system organization from the molecular to behavioral levels for species ranging from C. elegans to humans. In addition, the effects of development and neuropathological events are discussed. A final summary chapter synthesizes the data gathered in this volume in order to provide the basis for a general theory of neuroplasticity.

Cortical Plasticity: Theoretical Analysis, Experimental Results

Cortical Plasticity: Theoretical Analysis, Experimental Results PDF

Author: L. N. Cooper

Publisher:

Published: 1985

Total Pages: 34

ISBN-13:

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An account is given of a theory of and experimental results on development and modification of selectivity and ocular dominance in visual cortex. The single cell theory is generalized to be applicable to a neural network. Also discussed, in the context of the theoretical ideas, are experiments on the modifiability of inhibitory cells and on possible candidates for global controllers of learning. Keywords: Visual cortex; Cortical plasticity; Ocular dominance; Selectivity; GABA; Norepinephrine; and Acetylcholine.

In Vivo Optical Imaging of Brain Function

In Vivo Optical Imaging of Brain Function PDF

Author: Ron D. Frostig

Publisher: CRC Press

Published: 2009-05-06

Total Pages: 494

ISBN-13: 142007685X

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These are exciting times for the field of optical imaging of brain function. Rapid developments in theory and technology continue to considerably advance understanding of brain function. Reflecting changes in the field during the past five years, the second edition of In Vivo Optical Imaging of Brain Function describes state-of-the-art techniques a

Neural Models of Plasticity

Neural Models of Plasticity PDF

Author: John H. Byrne

Publisher: Academic Press

Published: 2013-10-22

Total Pages: 457

ISBN-13: 148321687X

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Neural Models of Plasticity: Experimental and Theoretical Approaches is an outgrowth of a conference that was held at Woods Hole, Massachusetts, in the spring of 1987. The purpose of that conference was to review recent developments in both areas and to foster communication between those researchers pursuing theoretical approaches and those pursuing more empirical approaches. Contributions have been solicited from individuals who represent both ends of the spectrum of approaches as well as those using a combination of the two. These indicate that our knowledge of the plastic capabilities of the nervous system is accelerating rapidly due to rapid advances in the understanding of basic subcellular and molecular mechanisms of plasticity, and because of the computational capabilities and plastic properties that emerge from neural networks and assemblies. The book contains 19 chapters and opens with a study on the role of the neuromodulator in associative learning of the marine mollusk Hermissend. Subsequent chapters examine topics such as learning and memory in Aplysia; the Hebb rule for synaptic plasticity; olfactory processing and associative memory in the mollusk Limax maximus; simulation of a classically conditioned response; and the neural substrates of memory, focusing on the role of the hippocampus.

Reprogramming the Cerebral Cortex

Reprogramming the Cerebral Cortex PDF

Author: Stephen G. Lomber

Publisher: Oxford University Press

Published: 2006-10-12

Total Pages: 461

ISBN-13: 019852899X

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The brain has a remarkable ability to adapt in the event of damage - in many cases shifting responsibility for specific cognitive functions to other non-damaged brain regions. This 'plasticity' can be crucial in aiding recovery from stroke, trauma, and peripheral damage such as eye or ear damage. Over the past thirty years our view of cortical plasticity has evolved greatly. Early studies suggested that changes to cortical function due to peripheral lesions could only occur duringdevelopment and that these plastic changes were specific to a particular temporal window or "critical period". Over time, it has been demonstrated that cortical modifications as a consequence of either peripheral or central lesions can induce adaptive, or beneficial, changes in cortical function in aneffort to preserve or enhance function. More recently, studies have identified that many of these adaptive changes, once thought only possible in the developing brain, are also possible in the mature or developed brain. At present, many laboratories are defining the beneficial capabilities of cerebral cortex plasticity, upon which many proactive and therapeutic strategies may be developed in order to maximiSe the "reprogramming" capabilities of the cerebrum.'Reprogramming the Cerebral Cortex' describes these exciting studies and examines adaptive cortical plasticity in a variety of systems (visual, auditory, somatomotor, cross-modal, language and cognition). The book leads the reader through the complexities and promise of neuroplasticity, and presents insights into current and future research and clinical practice. It is unique in looking at the beneficial capabilities of cerebral cortex plasticity, upon which many proactive and therapeuticstrategies may be developed.The book will be a valuable resource for behavioural, systems, computational and cognitive neuroscientists, as well as clinicians and neuropsychologists.

Translational Research in Traumatic Brain Injury

Translational Research in Traumatic Brain Injury PDF

Author: Daniel Laskowitz

Publisher: CRC Press

Published: 2015-12-01

Total Pages: 412

ISBN-13: 1498766579

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Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.