Cancer Clinical Trials

Cancer Clinical Trials PDF

Author: Tomasz M. Beer

Publisher: Diamedica

Published: 2012

Total Pages: 0

ISBN-13: 9780982321973

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A readable guide for anyone who is considering therapeutic options in addition to standard cancer therapy. The book seeks to share knowledge about cancer clinical trials with people living with cancer, their families and loved ones.

Transforming Clinical Research in the United States

Transforming Clinical Research in the United States PDF

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2010-10-22

Total Pages: 151

ISBN-13: 0309163358

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An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and the clinical research that guides medical decisions in the United States falls far short of this vision. The process of generating medical evidence through clinical trials in the United States is expensive and lengthy, includes a number of regulatory hurdles, and is based on a limited infrastructure. The link between clinical research and medical progress is also frequently misunderstood or unsupported by both patients and providers. The focus of clinical research changes as diseases emerge and new treatments create cures for old conditions. As diseases evolve, the ultimate goal remains to speed new and improved medical treatments to patients throughout the world. To keep pace with rapidly changing health care demands, clinical research resources need to be organized and on hand to address the numerous health care questions that continually emerge. Improving the overall capacity of the clinical research enterprise will depend on ensuring that there is an adequate infrastructure in place to support the investigators who conduct research, the patients with real diseases who volunteer to participate in experimental research, and the institutions that organize and carry out the trials. To address these issues and better understand the current state of clinical research in the United States, the Institute of Medicine's (IOM) Forum on Drug Discovery, Development, and Translation held a 2-day workshop entitled Transforming Clinical Research in the United States. The workshop, summarized in this volume, laid the foundation for a broader initiative of the Forum addressing different aspects of clinical research. Future Forum plans include further examining regulatory, administrative, and structural barriers to the effective conduct of clinical research; developing a vision for a stable, continuously funded clinical research infrastructure in the United States; and considering strategies and collaborative activities to facilitate more robust public engagement in the clinical research enterprise.

Assessment of Cancer Screening

Assessment of Cancer Screening PDF

Author: Pamela M. Marcus

Publisher: Springer Nature

Published: 2022

Total Pages: 138

ISBN-13: 3030945774

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Cancer screening is a prominent strategy in cancer control in the United States, yet the ability to correctly interpret cancer screening data eludes many researchers, clinicians, and policy makers. This open access primer rectifies that situation by teaching readers, in simple language and with straightforward examples, why and how the population-level cancer burden changes when screening is implemented, and how we assess whether that change is of benefit. This book provides an in-depth look at the many aspects of cancer screening and its assessment, including screening phenomena, performance measures, population-level outcomes, research designs, and other important and timely topics. Concise, accessible, and focused, Assessment of Cancer Screening: A Primer is best suited to those with education or experience in clinical research or public health in the United States - no previous knowledge of cancer screening assessment is necessary. This is the first text dedicated to cancer screening theory and methodology to be published in 20 years.

Experimental Leukemia and Mammary Cancer

Experimental Leukemia and Mammary Cancer PDF

Author: Charles Huggins

Publisher: University of Chicago Press

Published: 1979-04

Total Pages: 252

ISBN-13: 9780226358604

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Charles Brenton Huggins won the Nobel prize in 1966 for his extensive work in cancer research. He has spent fifty years at the laboratory bench exploring the nature of this disease in an attempt to understand and control it. In this volume, based almost exclusively on experiments conducted over the past twenty years at the University of Chicago, is both the record of Huggins's own research and, in Huggins's words, "a do-it-yourself guide for cancer research workers." Written simply and clearly so that the experiments can be easily reproduced, the book presents Huggins's experiments in the induction of breast cancer and leukemia in rodents. It also describes the methods he discovered to prevent cancer and to cure many of the cancers he has been able to induce. Although most of the material concerns breast cancer and leukemia, research on other kinds of tumors is also described.

The Study of Experimental Cancer, a Review

The Study of Experimental Cancer, a Review PDF

Author: William Henry 1879-1953 Woglom

Publisher: Palala Press

Published: 2016-05-04

Total Pages: 386

ISBN-13: 9781355439561

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This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

The Study of Experimental Cancer, Vol. 1

The Study of Experimental Cancer, Vol. 1 PDF

Author: William H. Woglom

Publisher: Forgotten Books

Published: 2018-02-13

Total Pages: 384

ISBN-13: 9780656473465

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Excerpt from The Study of Experimental Cancer, Vol. 1: A Review Chemical-studies have been omitted because a number of excellent reviews are already in existence, and because investigation in this field has thus far yielded but little of practical importance, while the bacteriological side of the question has been neglected for the reason that its discussion would amount to little more than a list of micro organisms. I desire to express my obligation to Dr. E. F. Bashford, Director of the Laboratories of the Imperial Cancer Research Fund, and to his colleagues, Dr. J. A. Murray and Dr. B. R. G. Russell; these gentlemen have read the book in manuscript and have made many valuable suggestions. The assistance of Dr. R. M. Rowe, of London, has been of the greatest value, while to Professor F. C. Wood, as well as to Dean Samuel W. Lambert, I am much indebted f-or continual advice and encouragement. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.

Hope and Suffering

Hope and Suffering PDF

Author: Gretchen Krueger

Publisher: JHU Press

Published: 2020-03-03

Total Pages: 229

ISBN-13: 1421429187

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Gretchen Krueger's poignant narrative explores how doctors, families, and the public interpreted the experience of childhood cancer from the 1930s through the 1970s. Pairing the transformation of childhood cancer from killer to curable disease with the personal experiences of young patients and their families, Krueger illuminates the twin realities of hope and suffering. In this social history, each decade follows a family whose experience touches on key themes: possible causes, means and timing of detection, the search for curative treatment, the merit of alternative treatments, the decisions to pursue or halt therapy, the side effects of treatment, death and dying—and cure. Recounting the complex and sometimes contentious interactions among the families of children with cancer, medical researchers, physicians, advocacy organizations, the media, and policy makers, Krueger reveals that personal odyssey and clinical challenge are the simultaneous realities of childhood cancer. This engaging study will be of interest to historians, medical practitioners and researchers, and people whose lives have been altered by cancer.

Cancer

Cancer PDF

Author: Rudolf Süss

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 306

ISBN-13: 1461298415

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This book really ought to be read on vacation, just for enjoyment. Granted, cancer is, literally, a deadly serious matter, and cancer research is primarily a part of medicine with Hippocrates in its back ground. Yet, cancer research is also natural science, and as such it yields the joys and sorrows of any science. The cancer problem is also a brain teaser, a challenge for the curious. This introductory report on experimental cancer research is there fore directed to curious students of many disciplines: naturally to medical students, but also to chemists and physicists who have an interest in biological phenomena; biology students will surely en counter pr9blems peculiar to their field in what is supposedly a medi cal one. We have attempted to write without assumptions to a certain degree, for a chemist is essentially in over his head in medicine, and a physician has only the slightest idea of the chemical problems im portant in cancer research. We had no intention of giving a complete view of the field, and from the large number of different lines of development we have chosen only a few. Chemotherapy, as an ex ample, has been treated quite cursorily, along with RNA tumor viruses, although it is possible that just these subjects are especially important for human tumors. Tumor induction via radiation could only be mentioned in passing, in spite of its great practical significance; similarly the role of hormones was only intimated.