The Semiotics of Cellular Communication in the Immune System

The Semiotics of Cellular Communication in the Immune System PDF

Author: Eli E. Sercarz

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 326

ISBN-13: 3642731457

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This volume contains the contributions to the workshop "The Semiotics of Cellular Communication in The Immune System" which took place at "11 Ciocco" in the hills north of Lucca, Italy, September ~-12, 1986. The workshop was the first meeting of what we hope will be a broad consideration of communication among lymphocytes, and focused on the new interdisciplinary branch of biological sciences, immunosemiotics. It is in the realm of the possible, if not the probable, that in the future a number of scientists larger than the thirty present at 11 Ciocco will find immunosemiotics to fill a need in scientific thinking and a gap between biology and the humanities. This might lead to growth and flourishing of the branch, and in this case the first conference and this first book could be blessed by the impalpable qual ity of becoming "historical", if in an admittedly 1 imited sense. Just in case this should happen the organizers/editors think it wise to set the record straight at this particular time, about the sequen~e of events and circumstances that crystallized the archeology of the "11 Liocco" gathering. They feel a sort of obligation to this endeavor: it has happened all too often that innocent historians have been left in utter confusion by the careless founders of new religions, schisms, revolutions, et cetera, who simply forget to jot down the facts before the whirlwind of time engulfs them in its fog.

Cell Communication in Nervous and Immune System

Cell Communication in Nervous and Immune System PDF

Author: Eckart D. Gundelfinger

Publisher: Springer Science & Business Media

Published: 2006-09-08

Total Pages: 320

ISBN-13: 3540368299

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This collection of reviews contains contributions by internationally recognized immunologists and molecular and cellular neurobiologists. Uniquely, it puts side by side cellular communication devices and signaling mechanisms in the immune and nervous systems and discusses mechanisms of interaction between the two systems, the significance of which has only recently been fully appreciated.

Cellular and Molecular Communication Networks within the Cutaneous Immune System

Cellular and Molecular Communication Networks within the Cutaneous Immune System PDF

Author: Tina Sumpter

Publisher: Frontiers Media SA

Published: 2023-09-01

Total Pages: 148

ISBN-13: 2832532934

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As the outermost barrier of the body, the skin protects against bacterial, viral, and environmental assaults. To reach this end, epidermal and dermal resident cells have evolved intricate communication networks, involving innate and adaptive immune cells, epithelial cells, and neurons. In disease states, skin resident cells are aided by recruited immune cells, such as neutrophils, basophils, and eosinophils. Initially, these cell types were studied in isolation, but recent focus has shifted towards understanding how physical interactions between cells and communication initiated by soluble mediators facilitate coordinated immune responses in the cutaneous microenvironment to maintain homeostasis, preserve barrier function, and, effectively clear bacterial, viral or fungal assailants. In this Research Topic, the goal is to highlight recent advances in cutaneous biology and immunology to provide insight into the cellular networks underlying the generation and regulation of cutaneous immune responses. Recent advances in this area have described novel pathways regulating skin-resident memory T cells, keratinocytes-immune cell interactions, and the relationships between sensory neurons and immune cells in the skin. Cumulatively, these studies provide a framework for understanding the complex interactions that are necessary for maintaining host protection, and homeostasis and reveal novel targetable pathways for patients with skin disease.

How the Immune System Recognizes Self and Nonself

How the Immune System Recognizes Self and Nonself PDF

Author: Daisuke Kitamura

Publisher: Springer Science & Business Media

Published: 2008-04-08

Total Pages: 264

ISBN-13: 4431738843

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How do you discriminate yourself from other people? This question must sound odd to you since you easily recognize others at a glance and, without any effort, would not mistake them for yourself. However, it is not always easy for some people to discriminate themselves from others. For example, patients with schi- phrenia often talk with “others” living inside themselves. Thus it is likely that n- mally your brain actively recognizes and remembers the information belonging to yourself and discriminates it from the information provided by others, although you are not conscious of it. This brain function must have been particularly important for most animals to protect their lives from enemies and for species to survive through evolution. Similarly, higher organisms have also acquired their immune system through evolution that discriminates nonself pathogens and self-body to protect their lives from pathogens such as bacteria or viruses. The brain system may distinguish integrated images of self and nonself created from many inputs, such as vision, sound, smell, and others. The immune system recognizes and distinguishes a variety of structural features of self and nonself components. The latter actually include almost everything but self: for example, bacteria, viruses, toxins, pollens, chemicals, transplanted organs, and even tumor cells derived from self-tissue. To this end the immune system recruits different kinds of immune cells, such as B and T lymphocytes, natural killer (NK) cells, dendritic cells, and macrophages.

Producing, sensing and responding to cellular stress in immunity

Producing, sensing and responding to cellular stress in immunity PDF

Author: Heitor A. Paula-Neto

Publisher: Frontiers Media SA

Published: 2019-11-28

Total Pages: 130

ISBN-13: 2889631427

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Cellular stress, being considered as any disturbance in cellular physiology, is a fundamental aspect of tissue and body capacity to adapt to the ever changing environment. It also surges as a consequence of tissue injury or invasion of the body by pathogens. Since the immune system was developed to sense and respond to these deleterious processes, it is reasonable to consider that immune cells are capable of sensing and responding to signs of cellular stress. Moreover, cells of the immune system undergo cellular stress during an immune response. This Research Topic presents a series of articles focusing on how cellular stress influences the outcome of immune responses, covering not only how cellular stress can be a fundamental process during immune cell activation and function, but also how cells of the immune system are capable of sensing and being influenced by factors produced by stressed cells.

Bloomsbury Semiotics Volume 2: Semiotics in the Natural and Technical Sciences

Bloomsbury Semiotics Volume 2: Semiotics in the Natural and Technical Sciences PDF

Author: Jamin Pelkey

Publisher: Bloomsbury Publishing

Published: 2023-01-12

Total Pages: 369

ISBN-13: 1350139343

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Bloomsbury Semiotics offers a state-of-the-art overview of the entire field of semiotics by revealing its influence on a wide range of disciplinary perspectives. With four volumes spanning theory, method and practice across the disciplines, this definitive reference work emphasizes and strengthens common bonds shared across intellectual cultures, and facilitates the discovery and recovery of meaning across fields. It comprises: Volume 1: History and Semiosis Volume 2: Semiotics in the Natural and Technical Sciences Volume 3: Semiotics in the Arts and Social Sciences Volume 4: Semiotic Movements Written by leading international experts, the chapters provide comprehensive overviews of the history and status of semiotic inquiry across a diverse range of traditions and disciplines. Together, they highlight key contemporary developments and debates along with ongoing research priorities. Providing the most comprehensive and united overview of the field, Bloomsbury Semiotics enables anyone, from students to seasoned practitioners, to better understand and benefit from semiotic insight and how it relates to their own area of study or research. Volume 2: Semiotics in the Natural and Technical Sciences presents the state-of-the art in semiotic approaches to disciplines ranging from mathematics and biology to neuroscience and medicine, from evolutionary linguistics and animal behaviour studies to computing, finance, law, architecture, and design. Each chapter casts a vision for future research priorities, unanswered questions, and fresh openings for semiotic participation in these and related fields.

Essential Readings in Biosemiotics

Essential Readings in Biosemiotics PDF

Author: Donald Favareau

Publisher: Springer Science & Business Media

Published: 2010-06-10

Total Pages: 882

ISBN-13: 140209650X

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Synthesizing the findings from a wide range of disciplines – from biology and anthropology to philosophy and linguistics – the emerging field of Biosemiotics explores the highly complex phenomenon of sign processing in living systems. Seeking to advance a naturalistic understanding of the evolution and development of sign-dependent life processes, contemporary biosemiotic theory offers important new conceptual tools for the scientific understanding of mind and meaning, for the development of artificial intelligence, and for the ongoing research into the rich diversity of non-verbal human, animal and biological communication processes. Donald Favareau’s Essential Readings in Biosemiotics has been designed as a single-source overview of the major works informing this new interdiscipline, and provides scholarly historical and analytical commentary on each of the texts presented. The first of its kind, this book constitutes a valuable resource to both bioscientists and to semioticians interested in this emerging new discipline, and can function as a primary textbook for students in biosemiotics, as well. Moreover, because of its inherently interdisciplinary nature and its focus on the ‘big questions’ of cognition, meaning and evolutionary biology, this volume should be of interest to anyone working in the fields of cognitive science, theoretical biology, philosophy of mind, evolutionary psychology, communication studies or the history and philosophy of science.

Immunity

Immunity PDF

Author: Hidetaka Yakura

Publisher: CRC Press

Published: 2024-08-05

Total Pages: 288

ISBN-13: 1040089569

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This book explores the essence of immunity. After an initial review of hypotheses, models, and theories proposed to explain immune phenomena in humans and mice, it summarizes the results from synchronic organism‐level analyses and diachronic analyses tracing phylogeny. These results suggest that immunity is coextensive with life and is equipped with functions similar to the nervous system. Philosophical reflection with reference to Spinoza and Canguilhem suggests immunity is part of the essence of life—and the essence of immunity embraces mental elements with normativity. Approaching the essence of any phenomenon in this way is called "metaphysicalization of science." This book demonstrates the potential of this approach and contributes to a richer understanding of nature. Key Features Reviews the history of immunological theories Discusses and integrates science and philosophy Provides a biological framework for cognition and self vs. nonself Inspired by Auguste Comte’s "The Law of Three Stages"

Selling Immunity Self, Culture and Economy in Healthcare and Medicine

Selling Immunity Self, Culture and Economy in Healthcare and Medicine PDF

Author: Mark Davis

Publisher: Routledge

Published: 2022-02-28

Total Pages: 157

ISBN-13: 1000542130

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Selling Immunity Self, Culture and Economy in Healthcare and Medicine provides a groundbreaking study of the ways in which immunity shapes life. Through its up-to-date discussion of immunity cultures, alongside detailed real-world examples, the book demonstrates how immunity is enmeshed in concepts of possessive individualism, self-defence and health consumerism. The book explores the rich metaphorical powers of immunity and the life narratives it inspires with reference to the talk of scientists, immunology texts and popular science magazines. The author provides a detailed overview of the ways in which digital media can shape the immune self with reference to cultural and social theories, providing insight into how immunitary knowledge and products are consumed and the benefits and drawbacks this has for healthcare. The book considers the significance of immunity for individuals navigating the threats to health that arise with pandemics and superbugs, with a keen look into how these ideas surface in everyday life across the globe. Finally, the book also discusses economic bases of healthcare technologies bent towards the protection and restoration of immunity. This book is essential reading for professionals within the fields of psychology, sociology, biomedical science, healthcare and other related disciplines. A broader audience will appreciate the book’s attention on the ways immunity is understood to be a personal possession, an object of life craft, and the basis for healthcare consumerism.

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