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The Role of Obesity in Cancer Survival and Recurrence

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2012-06-12

Total Pages: 126

ISBN-13: 0309253365

Recent research suggests that obesity and excess weight can play a prominent role in the incidence and progression of various cancers. Obesity results from an energy imbalance - that is, energy intake that is higher than energy expenditure - could also influence the growth of cancers. Recognizing the impact that current findings on obesity and cancer could have on future cancer prevention and care, the National Cancer policy Forum (NCPF) of the Institute of Medicine (IOM) help a 2-day workshop on "The Role of Obesity in Cancer Survival and Recurrence," in Washington, DC, on October 31 and November 1, 2011. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary reviews each presenter's latest clinical evidence on the obesity-cancer link and the molecular mechanisms that might explain that link. Clinicians, researchers, cancer survivors, and policy makers also discussed potential interventions to counter the effects of obesity on cancer, and research and policy measures needed to stem the rising tide of cancer mortality predicted by an increasingly overweight and older population worldwide. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary explores the complex web of molecular mechanisms that underlie the obesity-cancer link, the ways to design future studies to acquire the information needed to guide patient care, what to advise cancer patients about weight loss, diet, exercise, and other measures to reduce their risk of cancer progression or recurrence and policy suggestions related to research, education, and dissemination of the findings on obesity and cancer.

The Role of Obesity in Cancer Survival and Reoccurence

Author:

Publisher:

Published: 2012

Total Pages: 126

ISBN-13:

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"Recent research suggests that obesity and excess weight can play a prominent role in the incidence and progression of various cancers. Obesity results from an energy imbalance - that is, energy intake that is higher than energy expenditure - could also influence the growth of cancers. Recognizing the impact that current findings on obesity and cancer could have on future cancer prevention and care, the National Cancer policy Forum (NCPF) of the Institute of Medicine (IOM) help a 2-day workshop on "The Role of Obesity in Cancer Survival and Recurrence," in Washington, DC, on October 31 and November 1, 2011. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary reviews each presenter's latest clinical evidence on the obesity-cancer link and the molecular mechanisms that might explain that link. Clinicians, researchers, cancer survivors, and policy makers also discussed potential interventions to counter the effects of obesity on cancer, and research and policy measures needed to stem the rising tide of cancer mortality predicted by an increasingly overweight and older population worldwide. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary explores the complex web of molecular mechanisms that underlie the obesity-cancer link, the ways to design future studies to acquire the information needed to guide patient care, what to advise cancer patients about weight loss, diet, exercise, and other measures to reduce their risk of cancer progression or recurrence and policy suggestions related to research, education, and dissemination of the findings on obesity and cancer"--Publisher's description.

Physical Activity and Cancer

Author: Kerry S. Courneya

Publisher: Springer Science & Business Media

Published: 2010-11-26

Total Pages: 389

ISBN-13: 3642042317

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This book explores in depth the relation between physical activity and cancer control, including primary prevention, coping with treatments, recovery after treatments, long-term survivorship, secondary prevention, and survival. The first part of the book presents the most recent research on the impact of physical activity in preventing a range of cancers. In the second part, the association between physical activity and cancer survivorship is addressed. The effects of physical activity on supportive care endpoints (e.g., quality of life, fatigue, physical functioning) and disease endpoints (e.g., biomarkers, recurrence, survival) are carefully analyzed. In addition, the determinants of physical activity in cancer survivors are discussed, and behavior change strategies for increasing physical activity in cancer survivors are appraised. The final part of the book is devoted to special topics, including the relation of physical activity to pediatric cancer survivorship and to palliative cancer care.

Obesity and Cancer Recurrence Nutrition Education

Author: Jessica A. Norris

Publisher:

Published:

Total Pages: 84

ISBN-13:

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Oncology staff may not be aware of the importance of healthy weight maintenance to prevent cancer recurrence in breast, prostate and colorectal cancers due to the more acute attention to malnutrition and cachexia. Survivorship for breast, prostate and colorectal cancers are nearing the five year mark. Research is finding that weight gain and obesity may increase the risk of cancer, which can also increase survivors' risk of recurrence. It is crucial for oncology staff to be aware of the link between obesity or weight gain and cancer. A brief nutrition educational lecture by a Registered Dietitian on weight gain and obesity and cancer and cancer recurrence to oncology staff members was conducted to see if there was an improvement in scores in the awareness and appreciation of the link utilizing pre-test and post-test instruments. Objectives for intervention to oncology staff members included: Gain knowledge of body mass index classification, Demonstrate awareness of link between obesity and cancer, Gain knowledge in the links between obesity and weight gain and cancer recurrence, and Demonstrate awareness of the link between weight gain and risk of chronic diseases. The research was conducted utilizing a quasi-experimental design. A convenience population of subjects was asked to take a one time pre-test that was used to establish the subject's baseline knowledge. Then the subjects listened to a brief nutrition education lecture by a Registered Dietitian. After the lecture, the subjects took a one time post-test to evaluate knowledge gained from the nutrition education lecture. The results showed that staff did improve knowledge from improvement in mean score from 10.18 to 10.88 from pre-test to post-test. Further studies are needed to help facilitate education to cancer survivors, as well as health care professionals, about the importance of maintaining a healthy weight to prevent cancer recurrence.

Obesity and Breast Cancer Recurrence and Survival in Postmenopausal African-American Women

Author: Lori A. McNierney

Publisher:

Published: 1994

Total Pages: 124

ISBN-13:

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Weight Control and Physical Activity

Author: Harri Vainio

Publisher: IARC

Published: 2002

Total Pages: 346

ISBN-13: 9789283230069

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Avoiding overweight and obesity is the best-established diet-related risk factor for cancer. The proportion of people who are overweight/obese is increasing, and the amount of physical activity is decreasing in most populations, including urban populations in many developing countries. The increasing prevalence of overweight/obesity is presumably due to the increasing availability of highly palatable, high-energy foods, and an increasing sedentary lifestyle due to mechanisation of both workplace and leisure activities. Overweight/obesity and reduced physical activity increases the risk of cancers in various organs. Maintaining a healthy body weight and regular physical activity is the second most important way to prevent cancer, after tobacco control. The suggestions of possible public health actions to tackle these risk factors include the promotion of balanced diets, which are not excessive in energy, and broad education and planning to enable and encourage physical activity during work and leisure. Recommendations and a full discussion of these topics are included in the sixth volume in this series of Handbooks.

Breast Cancer Metastasis and Drug Resistance

Author: Aamir Ahmad

Publisher: Springer Nature

Published: 2019-08-27

Total Pages: 427

ISBN-13: 3030203018

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Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.

Role of Obesity in Human Health and Disease

Author: Venketeshwer Rao

Publisher: BoD – Books on Demand

Published: 2021-12-22

Total Pages: 209

ISBN-13: 183968979X

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Many factors influence obesity including genetic, environmental, and lifestyle factors. Studies have shown obesity to be related to increased risk of human diseases. Despite efforts by health professionals to regulate obesity, its prevalence has increased globally in the past few decades. A better understanding of the causes of obesity and mechanisms by which obesity increases the risk of human diseases can lead to developing effective strategies that can save many lives worldwide. This book addresses some important aspects of the relationship between obesity and human health. Chapters cover such topics as body mass index, endocrine disorders, obesity, and endometrial cancer, the role of lifestyle factors in obesity, and much more.

WHO Classification of Breast Tumours

Author: WHO Classification of Tumours Editorial Board

Publisher: International Agency for Research on Cancer

Published: 2019-11-21

Total Pages: 0

ISBN-13: 9789283245001

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Table of contents : - TNM staging of carcinomas of the breast - 1. Introduction to tumours of the breast - 2. Epithelial tumours of the breast - 3. Fibroepithelial tumours and hamartomas of the breast - 4. Tumours of the nipple - 5. Mesenchymal tumours of the breast - 6. Haematolymphoid tumours of the breast - 7. Tumours of the male breast - 8. Metastases to the breast - 9. Genetic tumours syndromes of the breast.

Cognitive-Behavioral Treatment of Obesity

Author: Zafra Cooper

Publisher: Guilford Press

Published: 2004-09-07

Total Pages: 232

ISBN-13: 9781593850920

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The first cognitive-behavioral treatment manual for obesity, this volume presents an innovative therapeutic model currently being evaluated in controlled research at Oxford University. From leading clinical researchers, the approach is specifically designed to overcome a major weakness of existing therapies: posttreatment weight regain. The book details powerful ways to help patients not only to achieve weight loss, but also to modify the problematic cognitions that undermine long-term weight control. Drawing on strategies proven effective with such problems as binge eating, the manual contains everything needed to implement the treatment: intervention guidelines, case examples, and reproducible handouts and forms.