The Role of Bioactive Lipids in Cancer, Inflammation and Related Diseases

The Role of Bioactive Lipids in Cancer, Inflammation and Related Diseases PDF

Author: Kenneth V. Honn

Publisher: Springer Nature

Published: 2019-09-27

Total Pages: 256

ISBN-13: 3030217353

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The Organizing Committee of the 15th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases compiled a group of junior investigators to provide reviews on the topics they presented at the Puerto Vallarta Bioactive Lipids conference, as part of the book series, Advances in Experimental Medicine and Biology (AEMB). The book in this series will be titled Bioactive Lipids in Cancer, Inflammation and Related Diseases. Topics range from all classes of lipids including prostaglandins, resolvins, spingolipids, P450-derived lipids, endocannabanoids and phospholipids. The focus includes physiology, cell biology, and structural studies in organisms from bacteria to humans and how these studies addressed the role of lipids in various disease i.e. cancer, inflammation, diabetes, obesity, cardiovascular disease and others.

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 5

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 5 PDF

Author: Kenneth V. Honn

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 592

ISBN-13: 1461501938

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This volume represents a collection of contributions from the 6th International Conference on Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Related Diseases held in Boston from September 12-15, 1999. The mission of this meeting was to bring together senior and junior investigators to both announce and examine their recent advancements in cutting-edge research on the roles and actions of lipid mediators and their impact in human physiology and disease pathogenesis. The meeting focused on new concepts in these areas of interest to both clinicians and researchers. The program included several outstanding plenary lectures and presentations by leading experts in the fields of cancer and inflammation. In addition, the Boston meeting presented three Young Investigator awards, one in each of the major focus areas. The meeting was exciting and proved to be very memorable. The program was developed with an emphasis on recent advances in molecular and of lipid mediators relevant in cellular mechanisims involved in the formation and actions inflammation and cancer. Plenary lectures were presented by Prof. Bengt Sammuelsson (Karolinska Institute, Stockholm; 1982 Nobel Laureate in Physiology or Medicine) and Prof. E. 1. Corey (Harvard University; 1990 Nobel Laureate in Chemistry). Both of these plenary lectures were held on Day 1, which set an exciting tone for this meeting. Immediately following these plenary lectures, three simultaneous breakout sessions were held, one of inflammation, a second on cancer and synthesis of novel inhibitors, and a third on enzymes-lipoxygenases/cyclooxygenases and inhibitors.

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury PDF

Author: Santosh Nigam

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 765

ISBN-13: 1461535204

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In recent decades eicosanoids have been attracting an increasing amount of attention as a result of their important physiological roles in many areas of biology and medicine. The eicosanoids comprise the prostaglandins, thromboxanes and leukotrienes and are products of arachidonic acid, an essential polyunsaturated fatty acid stored in tissue phospholipids. Disturbances of eicosanoids and their metabolic products play a regulatory role in many types of cell injuries and diseases. One of the most exciting areas of eicosanoid research pinpoints their participation in the control of cell proliferation and differentiation. Eicosanoids form a link between different fields of research into such areas as cancer, inflammation and radiation-induced injury. This link provided the impetus for the development of the conference series of which the present volume represents the proceedings of the Second International Conference, held in Berlin in October 1991.

Bioactive Lipids in Health and Disease

Bioactive Lipids in Health and Disease PDF

Author: Andres Trostchansky

Publisher: Springer

Published: 2019-05-28

Total Pages: 198

ISBN-13: 3030114880

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The purpose of this book is to introduce the readers on the perspective of the role that unsaturated fatty acids and complex lipids play on health and disease. Bioactive lipids can be modified affecting membrane composition, structure and fluidity in addition to changes in cell signaling associated to lipid-protein (membrane receptors) interactions, issues that are addressed by the authors. This book analyzes key topics involving bioactive lipids and their role in normal signaling and the mechanisms of disease. The book navigates from structural studies of oxidized and non-oxidized lipids to the reactions and cell signaling processes that bioactive lipids play in cardiovascular and neurodegenerative diseases. The book contains the recent advances reported in the literature about lipidomics as well as the role that lipid-derived compounds exert on unfolded protein response and lipid metabolism and disease. This book represents a state of the art introduction to lipid metabolism from a biochemical to an in vivo overview being an useful tool for students and investigators. We hope the mechanistic observations on the role of bioactive lipids in health and disease serve a perspective to improve the existing treatments or propose new lipid-based pharmacology

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2 PDF

Author: Kenneth V. Honn

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 542

ISBN-13: 1461553253

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Over one hundred contributions detail advances in the molecular and cellular biology of eicosanoid production, as well as their role in signal transduction. One of the most exciting developments explored within this collection of articles is the expression of the novel isoform of cyclooxygenase (cox-2), which may play a large role in the development of anti-inflammatory drugs.

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2 PDF

Author: Kenneth V. Honn

Publisher: Springer

Published: 1998-02-28

Total Pages: 555

ISBN-13: 9780306453601

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Over one hundred contributions detail advances in the molecular and cellular biology of eicosanoid production, as well as their role in signal transduction. One of the most exciting developments explored within this collection of articles is the expression of the novel isoform of cyclooxygenase (cox-2), which may play a large role in the development of anti-inflammatory drugs.

Bioactive Lipids and Lipidomics 2018

Bioactive Lipids and Lipidomics 2018 PDF

Author: Mario Ollero

Publisher: MDPI

Published: 2020-12-15

Total Pages: 296

ISBN-13: 3039362763

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After the coming of age of lipidomics, the science of global lipid analysis has broadened its contribution to the understanding of biological processes. This volume represents a transversal view on the state of the art of research on lipid biology and bioactive lipid molecules. It includes research and review articles on the role of bioactive lipids in diverse domains like cell signaling, neuromuscular transmission, cancer pathophysiology, cardiovascular and rare diseases, antibacterial activity, the emergency of biomaterials, and associated technological and analytical developments. It provides an instantaneous picture of the place of lipidomics and its fields of application, as well as hints about the directions that lipid research may follow in the near future.

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