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The Red Blood Cell
Author: Douglas MacN. Surgenor
Publisher:
Published: 1974
Total Pages:
ISBN-13: 9780126772500
DOWNLOAD EBOOK →Vertebrate Red Blood Cells
Author: Mikko Nikinmaa
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 273
ISBN-13: 3642839096
DOWNLOAD EBOOK →This book reviews the respiratory function of vertebrate red cells. I have defined the phrase "respiratory function" broadly to include, in addition to the actual oxygen and carbon dioxide transport, erythropoiesis, haemoglobin synthesis, red cell structure, the deformability of red cells in circulation, ion and substrate transport across the cell membrane, cellular metabolism, and control of cellular volume and pH. All of these aspects of the red cell function may affect gas transport between the respiratory epithelia and the tissues. Throughout the book, I have tried to relate our current knowledge about the nucleated red cell function to the wealth of information about the function of mammalian red cells. However, whenever possible, I have placed the emphasis on the nucleated red cell function for two reasons. First, the erythro cytes of 90% of vertebrate species are nucleated, and, second, nucleated red cell function has not been reviewed earlier in a single volume. This being the case, I have tried to make the reference list as complete as I could with regard to nucleated red cells. I hope that the approach adopted is useful for both com parative and human physiologists. Many people have contributed to the making of this book directly or in directly. Antti Soivio started me in this field. Prof. Henrik Wallgren has always encouraged fresh scientific ideas in his department. My present ideas of red cell function have been influenced by work carried out with Prof. Roy E.
Red Blood Cell Membranes
Author: Peter Agre
Publisher: CRC Press
Published: 1989-03-24
Total Pages: 768
ISBN-13: 9780824780227
DOWNLOAD EBOOK →This book is devoted to the red blood cell membrane, its structure and function, and abnormalities in disease states. It presents a well-documented and well-illustrated comprehensive picture of clinical manifestations of red blood cell disorders.
Computer Simulation Study of Collective Phenomena in Dense Suspensions of Red Blood Cells under Shear
Author: Timm Krüger
Publisher: Springer Science & Business Media
Published: 2012-10-02
Total Pages: 169
ISBN-13: 3834823767
DOWNLOAD EBOOK →The rheology of dense red blood cell suspensions is investigated via computer simulations based on the lattice Boltzmann, the immersed boundary, and the finite element methods. The red blood cells are treated as extended and deformable particles immersed in the ambient fluid. In the first part of the work, the numerical model and strategies for stress evaluation are discussed. In the second part, the behavior of the suspensions in simple shear flow is studied for different volume fractions, particle deformabilities, and shear rates. Shear thinning behavior is recovered. The existence of a shear-induced transition from a tumbling to a tank-treading motion is demonstrated. The transition can be parameterized by a single quantity, namely the effective capillary number. It is the ratio of the suspension stress and the characteristic particle membrane stress. At the transition point, a strong increase in the orientational order of the red blood cells and a significant decrease of the particle diffusivity are observed. However, the average cell deformation shows no signature of the transition.
The Red Blood Cell
Author: Douglas Surgenor
Publisher: Elsevier
Published: 2012-12-02
Total Pages: 629
ISBN-13: 0323161480
DOWNLOAD EBOOK →The Red Blood Cell, Second Edition, Volume I provides information pertinent to red blood cells, which is the most intensely studied human tissue. This book reviews the basic biomedical knowledge about the circulating, red blood cells. Organized into 13 chapters, this edition starts with an overview of the discovery of red blood cells, which results in the growth of knowledge in the areas of clinical disease and therapeutic efforts. This book then discusses the significant functions of the red blood cells, which exists basically to transport the respiratory gases. Other chapters examine the red blood cell’s capacity for protein synthesis and its ability to diversify its function. This book discusses as well the progress in the structural analysis of lipids. The final chapter deals with the capacity to store red blood cells frozen for long periods with high yield of viable physiological functional cells after post-thaw processing. Scientists, physicians, teachers, researchers, and students will find this book extremely useful.
Red Blood Cell Aggregation
Author: Oguz Baskurt
Publisher: CRC Press
Published: 2011-09-28
Total Pages: 326
ISBN-13: 1439841802
DOWNLOAD EBOOK →Red blood cells in humans—and most other mammals—have a tendency to form aggregates with a characteristic face-to-face morphology, similar to a stack of coins. Known as rouleaux, these aggregates are a normally occurring phenomenon and have a major impact on blood rheology. What is the underlying mechanism that produces this pattern? Does this really happen in blood circulation? And do these rouleaux formations have a useful function? The first book to offer a comprehensive review of the subject, Red Blood Cell Aggregation tackles these and other questions related to red blood cell (RBC) aggregates. The book covers basic, clinical, and physiological aspects of this important biophysical phenomenon and integrates these areas with concepts in bioengineering. It brings together state-of-the-art research on the determinants, mechanisms, and measurement and effects of RBC aggregation as well as on variations and comparative aspects. After an introductory overview, the book outlines factors and conditions that affect RBC aggregation. It presents the two hypotheses—the bridging model and the depletion model—that provide potential mechanisms for the adhesive forces that lead to the regular packing of the cells in rouleaux formations. The book also reviews the methods used to quantify RBC aggregation in vitro, focusing on their importance in clinical practice. Chapters discuss the effect of RBC aggregation on the in vitro rheology of blood as well as on tube flow. The book also looks at what happens in the circulation when red blood cells aggregate and examines variations due to physiological and pathophysiological challenges. The concluding chapter explores the formation of red blood cell aggregates in other mammals. Written by leading researchers in the field, this is an invaluable resource for basic science, medical, and clinical researchers; graduate students; and clinicians interested in mammalian red blood cells.
Clinical Methods
Author: Henry Kenneth Walker
Publisher: Butterworth-Heinemann
Published: 1990
Total Pages: 1128
ISBN-13:
DOWNLOAD EBOOK →A guide to the techniques and analysis of clinical data. Each of the seventeen sections begins with a drawing and biographical sketch of a seminal contributor to the discipline. After an introduction and historical survey of clinical methods, the next fifteen sections are organized by body system. Each contains clinical data items from the history, physical examination, and laboratory investigations that are generally included in a comprehensive patient evaluation. Annotation copyrighted by Book News, Inc., Portland, OR
Regulation of Tissue Oxygenation, Second Edition
Author: Roland N. Pittman
Publisher: Biota Publishing
Published: 2016-08-18
Total Pages: 117
ISBN-13: 1615047212
DOWNLOAD EBOOK →This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Cell Membrane
Author: Yoshihito Yawata
Publisher: John Wiley & Sons
Published: 2006-01-24
Total Pages: 454
ISBN-13: 3527605320
DOWNLOAD EBOOK →This publication presents the structure and function of biological membranes to improve the understanding of cells in both normal and pathogenic states. Recently, vast amounts of new information have been accumulated, especially about pathological conditions, and there is now much evidence correlating genotypes and phenotypes in normal and disease states. This book surveys the most recent findings in research on the molecular biology, biochemistry, and genetics of the membranes of human red blood cells.
