The Physiological Basis of Memory

The Physiological Basis of Memory PDF

Author: J. Anthony Deutsch

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 448

ISBN-13: 0323149960

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The Physiological Basis of Memory, Second Edition reviews many areas of research that shed light on the physiological basis of memory, from mnemonic function and memory facilitation to synaptic transmission. The book also considers neuropsychology involving animal subjects, learning produced by direct brain stimulation, and the basis of associative learning at the cellular level. This edition is organized into 10 chapters and begins with an overview of the link between protein synthesis and memory, paying attention to studies devoted to chemical changes associated with learning; the effect of inhibitors of RNA and protein synthesis on learning; the molecular code of memory; and the role of proteins in learning. The reader is methodically introduced to the enhancement of memory consolidation; the use of the cellular-connection approach to investigate both non-associative and associative learning; and the effect of depression on memory storage. The following chapters discuss the impact of brain lesions on animal memory; the neurology of memory and amnesia in human and nonhuman primates; the function of the neural substrate for self-stimulation of the medial forebrain bundle; and the effects of electroconvulsive shock on memory. A chapter on the role of catecholamines in memory processing concludes the book. This book should be useful to researchers and students interested in the physiology of memory.

Discovering the Brain

Discovering the Brain PDF

Author: National Academy of Sciences

Publisher: National Academies Press

Published: 1992-01-01

Total Pages: 195

ISBN-13: 0309045290

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The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Neural Plasticity and Memory

Neural Plasticity and Memory PDF

Author: Federico Bermudez-Rattoni

Publisher: CRC Press

Published: 2007-04-17

Total Pages: 368

ISBN-13: 1420008412

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A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq

Mechanisms of Memory

Mechanisms of Memory PDF

Author: J. David Sweatt

Publisher: Academic Press

Published: 2009-09-28

Total Pages: 362

ISBN-13: 0080959199

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This fully revised second edition provides the only unified synthesis of available information concerning the mechanisms of higher-order memory formation. It spans the range from learning theory, to human and animal behavioral learning models, to cellular physiology and biochemistry. It is unique in its incorporation of chapters on memory disorders, tying in these clinically important syndromes with the basic science of synaptic plasticity and memory mechanisms. It also covers cutting-edge approaches such as the use of genetically engineered animals in studies of memory and memory diseases. Written in an engaging and easily readable style and extensively illustrated with many new, full-color figures to help explain key concepts, this book demystifies the complexities of memory and deepens the reader’s understanding. More than 25% new content, particularly expanding the scope to include new findings in translational research. Unique in its depth of coverage of molecular and cellular mechanisms Extensive cross-referencing to Comprehensive Learning and Memory Discusses clinically relevant memory disorders in the context of modern molecular research and includes numerous practical examples

Learning and Memory

Learning and Memory PDF

Author: Joe L. Jr. Martinez

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 471

ISBN-13: 0323149170

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Learning and Memory: A Biological View is a comprehensive textbook about the neurobiology of learning and memory. Topics covered include developmental approaches to the memory process; anatomical correlates of neuronal plasticity; drugs that modulate learning and memory; and biochemical correlates of learning and memory. The link between aging and memory is also discussed, along with electrophysiological approaches to the study of memory. Comprised of 12 chapters, this book begins with a review of historical traditions that influenced research on the biological basis of learning and memory. Experimental findings suggesting that the engram for a simple classically conditioned skeletal response may be in the cerebellum are also presented. The next chapter emphasizes the importance of anatomical mechanisms that could mediate learning, plasticity, and memory storage in young and adult animals. Subsequent chapters explore the influence of peripheral hormones and particularly opioid peptides on complex behavior such as learning and memory; the contribution of individual neurotransmitter systems to learning; the psychopathology of aging; and long-term potentiation as a model of the way the central nervous system stores information. Learning in complex vertebrate systems and direct stimulation of various brain nuclei are also examined. The final chapter presents a neurobehavioral analysis of the structure of memory formation that utilizes lesions and explores human memory pathology. This monograph is intended for advanced undergraduate students, graduate students, and research workers in the field of memory.

The Seven Sins of Memory

The Seven Sins of Memory PDF

Author: Daniel L. Schacter

Publisher: HMH

Published: 2002-05-07

Total Pages: 289

ISBN-13: 0547347456

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A New York Times Notable Book: A psychologist’s “gripping and thought-provoking” look at how and why our brains sometimes fail us (Steven Pinker, author of How the Mind Works). In this intriguing study, Harvard psychologist Daniel L. Schacter explores the memory miscues that occur in everyday life, placing them into seven categories: absent-mindedness, transience, blocking, misattribution, suggestibility, bias, and persistence. Illustrating these concepts with vivid examples—case studies, literary excerpts, experimental evidence, and accounts of highly visible news events such as the O. J. Simpson verdict, Bill Clinton’s grand jury testimony, and the search for the Oklahoma City bomber—he also delves into striking new scientific research, giving us a glimpse of the fascinating neurology of memory and offering “insight into common malfunctions of the mind” (USA Today). “Though memory failure can amount to little more than a mild annoyance, the consequences of misattribution in eyewitness testimony can be devastating, as can the consequences of suggestibility among pre-school children and among adults with ‘false memory syndrome’ . . . Drawing upon recent neuroimaging research that allows a glimpse of the brain as it learns and remembers, Schacter guides his readers on a fascinating journey of the human mind.” —Library Journal “Clear, entertaining and provocative . . . Encourages a new appreciation of the complexity and fragility of memory.” —The Seattle Times “Should be required reading for police, lawyers, psychologists, and anyone else who wants to understand how memory can go terribly wrong.” —The Atlanta Journal-Constitution “A fascinating journey through paths of memory, its open avenues and blind alleys . . . Lucid, engaging, and enjoyable.” —Jerome Groopman, MD “Compelling in its science and its probing examination of everyday life, The Seven Sins of Memory is also a delightful book, lively and clear.” —Chicago Tribune Winner of the William James Book Award

Molecular Basis of Memory

Molecular Basis of Memory PDF

Author:

Publisher: Academic Press

Published: 2014-01-30

Total Pages: 467

ISBN-13: 0124202004

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This special volume of Progress in Molecular Biology and Translational Science provides a current overview of how memory is processed in the brain. A broad range of topics are presented by leaders in the field, ranging from brain circuitry to synaptic plasticity to the molecular machinery that contributes to the brain's ability to maintain information across time. Memory systems in the prefrontal cortex, hippocampus and amygdala are considered as well. In addition, the volume covers recent contributions to our understanding of memory from in vivo imaging, optogenetic, electrophysiological, biochemical and molecular biological studies. Articles from world renowned experts in memory Covering topics from signaling, epigenetic, RNA translation to plasticity Methodological approaches include molecular and cellular, behavioral, electrophysiological, optogenetic and functional imaging

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