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Structure and Physics of Viruses

Author: Mauricio G. Mateu

Publisher: Springer Science & Business Media

Published: 2013-06-04

Total Pages: 734

ISBN-13: 9400765525

This book contemplates the structure, dynamics and physics of virus particles: From the moment they come into existence by self-assembly from viral components produced in the infected cell, through their extracellular stage, until they recognise and infect a new host cell and cease to exist by losing their physical integrity to start a new infectious cycle. (Bio)physical techniques used to study the structure of virus particles and components, and some applications of structure-based studies of viruses are also contemplated. This book is aimed first at M.Sc. students, Ph.D. students and postdoctoral researchers with a university degree in biology, chemistry, physics or related scientific disciplines who share an interest or are actually working on viruses. We have aimed also at providing an updated account of many important concepts, techniques, studies and applications in structural and physical virology for established scientists working on viruses, irrespective of their physical, chemical or biological background and their field of expertise. We have not attempted to provide a collection of for-experts-only reviews focused mainly on the latest research in specific topics; we have not generally assumed that the reader knows all of the jargon and all but the most recent and advanced results in each topic dealt with in this book. In short, we have attempted to write a book basic enough to be useful to M.Sc and Ph.D. students, as well as advanced and current enough to be useful to senior scientists with an interest in Structural and/or Physical Virology.

The Physics of Viruses

Author: Ernest Charles Pollard

Publisher:

Published: 1954

Total Pages: 7

ISBN-13:

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The Physics of Viruses

Author: Ernest C. Pollard

Publisher: Academic Press

Published: 2013-10-22

Total Pages: 243

ISBN-13: 1483270920

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The Physics of Viruses presents what is known about viruses from the viewpoint of a physicist. In so doing, a major aim has proved to be the description of viruses, their shape, and structure. Rather surprisingly, definite shapes and structures are emerging, and it is with a heightened sense of excitement that the hoped-for simplicity and symmetry are beginning to be found. The book contains eight chapters and opens with a discussion of the nature of viruses and their relation to physics. Subsequent chapters present studies on the size, shape, and hydration of viruses; the effects of ionizing radiation on viruses, thermal inactivation of viruses, biological effects of ultraviolet light, sonic and osmotic effects on viruses, and virus genetics and multiplication. The account given here should interest not only the physicist but that growing body of students who admit to being virologists as well. There is no doubt that the processes of viruses are in some way the processes of biology, so that the fundamental actions of biology may well be clarified by thinking about how viruses perform their work.

The Physics of Viruses

Author: Ernest C 1906- Pollard

Publisher: Palala Press

Published: 2015-09-06

Total Pages: 248

ISBN-13: 9781341771217

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This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Viruses

Author: Paula Tennant

Publisher: Academic Press

Published: 2018-03-12

Total Pages: 392

ISBN-13: 0128111941

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Viruses: Molecular Biology, Host Interactions, and Applications to Biotechnology provides an up-to-date introduction to human, animal and plant viruses within the context of recent advances in high-throughput sequencing that have demonstrated that viruses are vastly greater and more diverse than previously recognized. It covers discoveries such as the Mimivirus and its virophage which have stimulated new discussions on the definition of viruses, their place in the current view, and their inherent and derived ‘interactomics’ as defined by the molecules and the processes by which virus gene products interact with themselves and their host’s cellular gene products. Further, the book includes perspectives on basic aspects of virology, including the structure of viruses, the organization of their genomes, and basic strategies in replication and expression, emphasizing the diversity and versatility of viruses, how they cause disease and how their hosts react to such disease, and exploring developments in the field of host-microbe interactions in recent years. The book is likely to appeal, and be useful, to a wide audience that includes students, academics and researchers studying the molecular biology and applications of viruses Provides key insights into recent technological advances, including high-throughput sequencing Presents viruses not only as formidable foes, but also as entities that can be beneficial to their hosts and humankind that are helping to shape the tree of life Features exposition on the diversity and versatility of viruses, how they cause disease, and an exploration of virus-host interactions

The Physics of Viruses

Author: Ernest C (Ernest Charles) Pollard

Publisher: Hassell Street Press

Published: 2021-09-09

Total Pages: 254

ISBN-13: 9781013710155

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This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Harnessing the Power of Viruses

Author: Boriana Marintcheva

Publisher: Academic Press

Published: 2017-11-13

Total Pages: 296

ISBN-13: 0128105151

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Harnessing the Power of Viruses explores the application of scientific knowledge about viruses and their lives to solve practical challenges and further advance molecular sciences, medicine and agriculture. The book contains virus-based tools and approaches in the fields of: i) DNA manipulations in vitro and in vivo; ii) Protein expression and characterization; and iii) Virus- Host interactions as a platform for therapy and biocontrol are discussed. It steers away from traditional views of viruses and technology, focusing instead on viral molecules and molecular processes that enable science to better understand life and offer means for addressing complex biological phenomena that positively influence everyday life. The book is written at an intermediate level and is accessible to novices who are willing to acquire a basic level of understanding of key principles in molecular biology, but is also ideal for advanced readers interested in expanding their biological knowledge to include practical applications of molecular tools derived from viruses. Explores virus-based tools and approaches in DNA manipulation, protein expression and characterization and virus-host interactions Provides a dedicated focus on viral molecules and molecular processes that enable science to better understand life and address complex biological phenomena Includes an overview of modern technologies in biology that were developed using viral components/elements and knowledge about viral processes

Structural Virology

Author: Mavis Agbandje-McKenna

Publisher: Royal Society of Chemistry

Published: 2010-11-11

Total Pages: 388

ISBN-13: 184973223X

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Over the last ten years, much effort has been devoted to improving the biophysical techniques used in the study of viruses. This has resulted in the visualization of these large macromolecular assemblages at atomic level, thus providing the platform for functional interpretation and therapeutic design. Structural Virology covers a wide range of topics and is split into three sections. The first discusses the vast biophysical methodologies used in structural virology, including sample production and purification, confocal microscopy, mass spectrometry, negative-stain and cryo-electron microscopy, X-ray crystallography and nuclear magnetic resonance spectroscopy. The second discusses the role of virus capsid protein structures in determining the functional roles required for receptor recognition, cellular entry, capsid assembly, genome packaging and mechanisms of host immune system evasion. The last section discusses therapeutic strategies based on virus protein structures, including the design of antiviral drugs and the development of viral capsids as vehicles for foreign gene delivery. Each topic covered will begin with a review of the current literature followed by a more detailed discussion of experimental procedures, a step in the viral life cycle, or strategies for therapeutic development. With contributions from experts in the field of structural biology and virology this exceptional monograph will appeal to biomedical scientists involved in basic and /or applied research on viruses. It also provides up-to-date reference material for students entering the field of structural virology as well as scientists already familiar with the area.

Structure and Physics of Viruses

Author: Mauricio G. Mateu

Publisher: Springer

Published: 2024-11-14

Total Pages: 0

ISBN-13: 9783031651861

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The second edition of this book provides a completely updated account of the structure, dynamics, and physics of viral particles: from the moment they emerge by self-assembly from viral components produced in the infected cell, through their extracellular stage, until they recognize and infect a new host cell and cease to exist as they lose their physical integrity to initiate a new infectious cycle. New insights into the structure of viruses, their physical properties, and mechanisms of action, derived from results obtained in the last decade, have been included, as well as other (bio)physical techniques to study the structure or dynamics of virus particles and components. These include new advances in high-resolution electron cryomicroscopy; novel approaches in the use of electron cryotomography or the application of soft X-ray tomography to study viruses in the infected cell; high-speed atomic force microscopy to study virus assembly and dynamics. The development of antiviral drugs and vaccines with virus-like particles. New chapters on the technological applications of modified viral particles or the physical study of the virus-liquid interface have been included in this second edition, which is still aimed primarily at Master's students, Ph.D. students, and postdoctoral researchers with degrees in biology, chemistry, physics or related scientific disciplines who have an interest in or are working with viruses, providing an up-to-date overview of many important concepts, techniques, studies and applications in structural and physical virology for specialized researchers working with viruses, regardless of their field of specialization, covering the latest research together with fundamental concepts and well-established facts. In short, this book is basic enough to be used by undergraduate and Ph.D. students, but advanced and up-to-date enough for experienced scientists with an interest in structural and/or physical virology.

A Planet of Viruses

Author: Carl Zimmer

Publisher: University of Chicago Press

Published: 2015-10-06

Total Pages: 133

ISBN-13: 022632026X

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For years, scientists have been warning us that a pandemic was all but inevitable. Now it's here, and the rest of us have a lot to learn. Fortunately, science writer Carl Zimmer is here to guide us. In this compact volume, he tells the story of how the smallest living things known to science can bring an entire planet of people to a halt--and what we can learn from how we've defeated them in the past. Planet of Viruses covers such threats as Ebola, MERS, and chikungunya virus; tells about recent scientific discoveries, such as a hundred-million-year-old virus that infected the common ancestor of armadillos, elephants, and humans; and shares new findings that show why climate change may lead to even deadlier outbreaks. Zimmer’s lucid explanations and fascinating stories demonstrate how deeply humans and viruses are intertwined. Viruses helped give rise to the first life-forms, are responsible for many of our most devastating diseases, and will continue to control our fate for centuries. Thoroughly readable, and, for all its honesty about the threats, as reassuring as it is frightening, A Planet of Viruses is a fascinating tour of a world we all need to better understand.