The Pathobiology of Neoplasia

The Pathobiology of Neoplasia PDF

Author: A.E. Sirica

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 591

ISBN-13: 1468455230

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This book is directed primarily to advanced graduate and medical students, postdoctoral trainees, and established investigators having basic research interests in neoplasia. Its content is based in part on the lecture outlines and selected histopathology laboratory components of an advanced course entitled The Pathobiology of Experimental Animal and Human Neoplasia, developed by me for the Experimental Pathology Curriculum of the Department of Pathology at the Medical College of Virginia. In this regard, an effort has been made to integrate pathology with carcinogenesis, genetics, biochemistry, and cellular and molecular biology in order to present a comprehensive and current view of the neoplastic process. For focus, emphasis is mainly being placed on the neoplastic cells themselves, and not on associated host-mediated responses. It ishoped that this book will accomplish its purpose of providing students and researchers who already possess strong but diverse basic science backgrounds with unifying concepts in tumor pathobiology, so as to stimulate new research aimed at furthering our understanding of neoplastic disease. I wish to express my appreciation and heartfelt thanks to the authors, whose individual ranges of expertise and research experience clearly bring to their respective chapters unique perspectives that easily transcend any redundancy that may be present. In addition, I am grateful to Drs. George Vennart, Saul Kay, and Fred Meier, and to Ms. Connie Wilkerson of the Department of Pathology at MCV, for their helpful comments and their review of some of the material.

Pathobiology of Human Germ Cell Neoplasia

Pathobiology of Human Germ Cell Neoplasia PDF

Author: J. Wolter Oosterhuis

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 281

ISBN-13: 3642844855

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Pathobiology of Human Germ Cell Neoplasia is a state-of-the-art compendium on a very recent branch of tumor biology. It offers an awareness and understanding of germ cell tumors: from the earliest stages to their va- rious differentiations. Original data for this volume was supplied by experts in the fields of pathology, developmental biology, genetics, molecular biology and other related fields. This compilation of knowledge provides information necessary to persons working in clinical and preclinical areas.

Pathology: The Big Picture

Pathology: The Big Picture PDF

Author: William Kemp

Publisher: McGraw Hill Professional

Published: 2007-08-22

Total Pages: 458

ISBN-13: 0071593799

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Get the BIG PICTURE of Pathology - and focus on what you really need to know to score high on the course and board exam If you want a streamlined and definitive look at Pathology - one with just the right balance of information to give you the edge at exam time - turn to Pathology: The Big Picture. You'll find a succinct, user-friendly presentation especially designed to make even the most complex concept understandable in the shortest amount of study time possible. This perfect pictorial and textual overview of Pathology delivers: A “Big Picture” emphasis on what you must know verses “what's nice to know” Expert authorship by award-winning, active instructors Coverage of the full range of pathology topics - everything from cellular adaptations and injury to genetic disorders to inflammation to diseases of immunity Magnificent 4-color illustrations Numerous summary tables and figures for quick reference and rapid retention of even the most difficult topic Highlighted key concepts that underscore integral aspects of histology (key concepts are also listed in a table at the end of each chapter) USMLE-type questions, answers, and explanations to help you anticipate what you'll encounter on the exams And much more!

Pathology of Incipient Neoplasia

Pathology of Incipient Neoplasia PDF

Author: Donald Earl Henson

Publisher: Oxford University Press

Published: 2001-01-25

Total Pages: 868

ISBN-13: 9780199771721

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Many malignant tumors have a morphologically recognizable precursor lesion. As screening and early detection have improved our ability to detect lesions at increasingly earlier stages of growth, an increased number of precancerous lesions are seen by pathologists. Unfortunately, a lack of uniform histologic criteria for precursors found in many organs can make diagnostic interpretation difficult. It is evident that physicians are seeking a better understanding of the genesis and progression of these lesions and their early biology, to provide optimal treatment and patient care. Pathology of Incipient Neoplasia 3E brings together all of the information available on the clinicopathologic features of precancerous lesions, defined to include atypical hyperplasias, in-situ changes, microinvasive or very small cancers in some sites, and other lesions recognized as potential precursors for invasive cancer. In some tissues, benign tumors may serve as precursors to malignant tumors, and therefore these also are considered. Organized by organ, each heavily-illustrated chapter is written by a well-recognized expert, to stress different facets of preneoplasia and minimally invasive tumors in that given tissue. Areas where strides have been made in research on molecular biologic aspects of neoplasia are discussed in conjunction with morphologic parameters. A chapter on salivary glands, and more than 350 color photos interspersed throughout the text, are new to this edition.

Pathology of Incipient Neoplasia

Pathology of Incipient Neoplasia PDF

Author: Donald Earl Henson

Publisher:

Published: 1993

Total Pages: 600

ISBN-13:

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A useful resource for the diagnosis and treatment of the early stages of cancer, this excellent book provides vital information for the early recognition of cancerous lesions. Coverage includes the lymphoid system, the small and large intestine, the central nervous system, soft tissue, bone, neuroblastoma, neuroendocrine, Wilms' tumor, the breast, kidney, and more. New to this edition is coverage of molecular pathology, many new chapters on different body sites, as well as many chapters completely rewritten by eminent authors, and new techniques throughout. Written by top-notch surgical pathologists who have extensive experience in each organ system or tissue area under study.Covers in detail the early stages of human cancer. Detailed discussions of clinical pathological features include information on DNA analysis by flow cytometry and its usefulness in diagnosis and prognosis.

Neoplastic Mimics in Thoracic and Cardiovascular Pathology

Neoplastic Mimics in Thoracic and Cardiovascular Pathology PDF

Author: Mark R. Wick, MD

Publisher: Demos Medical Publishing

Published: 2013-03-26

Total Pages: 239

ISBN-13: 1620700131

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" Neoplastic mimics or ìpseudotumorsî can simulate neoplasms on all levels of analysisóclinical, radiologic, and pathologicóand thus represent particular diagnostic pitfalls for the pathologist that can ultimately lead to therapeutic misdirection. Hundreds of color images and analysis of diagnostic mimics guide the pathologist through recognizing and distinguishing the unusual variants, morphologic anomalies, and misleading features that may easily lead to an inaccurate interpretation and missed diagnosis. Since many of the entities described are uncommon, Neoplastic Mimics in Thoracic and Cardiovascular Pathology emphasizes imaging and clinical correlations throughout to support the pathologist as consultant to the entire diagnostic and clinical management team. Every pathologist who sees skin cases will find this book an invaluable working tool to ensure accurate diagnosis. This book provides the pathologist with detailed morphologic descriptions and diagnostic guidance in recognizing these neoplastic mimics as they occur in the skin. In addition, descriptions and diagnostic guidance are provided for the range of skin lesions that may mimic benign masses but are in fact neoplastic. Throughout the book comparisons of neoplastic mimics with true neoplasms are provided, at clinical, gross, and histologic levels. In the presentation of every entity, the points that contribute to differential diagnosis are emphasized. Neoplastic Mimics in Dermatopathology Features: Nearly 500 high-quality images showcase the full range of nonneoplastic and neoplastic mimics in skin Concise, specific text descriptions to make the book easy to use as a visual reference Expert authors guide the reader to recognizing and distinguishing misleading specimens "

Pediatric Neoplasia

Pediatric Neoplasia PDF

Author: Alexander Craig Mackinnon Jr

Publisher: Springer Science & Business Media

Published: 2012-10-26

Total Pages: 273

ISBN-13: 1627031162

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Pediatric Neoplasia: Advances in Molecular Pathology and Translational Medicine presents many of the major, relevant advances in molecular pathology that are occurring in the field of pediatric oncology and will serve as a useful overview for resident and attending physicians as well as scientists interested in understanding the molecular pathology of pediatric cancer in the context of clinical medicine. Chapters are based upon organ systems, and each is written by an expert or pair of experts in their field with subspecialty training and extensive clinical experience. Each chapter describes a variable number of tumors and includes an overview of the classification system and clinicopathological characteristics of each tumor. This is followed by a discussion of the molecular pathology relevant to a specific tumor, including specific molecular markers of the tumors, methods used for diagnosis or clinical management, clinical significance of the markers, and if appropriate, a description or discussion of current activities in translational research or issues that need to be addressed in the future. Pediatric Neoplasia: Advances in Molecular Pathology and Translational Medicine will be of great value to pathologists, oncologists, hematologists, internal medicine and pediatric specialists, as well as pharmaceutical professionals and translational and clinical researchers.

Pathology

Pathology PDF

Author: John H. Holliman

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 240

ISBN-13: 1468403222

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These notes were developed to assist in the review of the basic science of pathology for those students preparing to sit for various national proficiency examinations which include, as part of their content, material dealing with general and systemic pathology. As such, the notes are not intended to replace the many fine textbooks of pathology whose scope, detail, and mission are more suited to the in depth study of pathology. Rather, these notes are intended to serve as "memory joggers" to rekindle and refresh the mind of some of the salient features of various disease processes and to point out to the student possible areas of weakness which they may need to address in more detail by referring to one of the standard textbooks of pathology. In this regard, these notes are presented in an organized and sensible (we hope!) outline format which is intended to allow systematic review of the material in a reasonable amount of time. In an effort to contain cost and avoid undue repetition with other volumes of the Oklahoma Notes series, some topics that are generally covered in most standard pathology courses as well as illustrative material have been omitted from the present edition. The authors would like to extend our sincere gratitude to the faculty and staff of the Department of Pathology for their ideas, support, and assistance during the preparation of these notes. In particular, we would like to thank Drs. K.

Diagnostic Pathology of Pleuropulmonary Neoplasia

Diagnostic Pathology of Pleuropulmonary Neoplasia PDF

Author: Annikka Weissferdt

Publisher: Springer Science & Business Media

Published: 2012-11-13

Total Pages: 475

ISBN-13: 1441907874

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Diagnostic Pathology of Pleuropulmonary Neoplasia highlights the morphologic basis, immunohistochemistry, electron microscopy, and molecular biology of tumoral and pseudotumoral conditions of the lung and pleura. The volume also highlights the nuances in the diagnosis of lung and pleural conditions and the applications of today’s most recent studies in molecular biology, and the way it is applied to diagnosis and treatment. In providing an expert guide for the histopathologic diagnosis of lung and pleural tumors, this volume be of great interest to general surgical pathologists, surgeons, oncologists, and those involved in the management of patients with lung tumors.