The Organic Chemistry of Drug Synthesis, 6 Volume Set

The Organic Chemistry of Drug Synthesis, 6 Volume Set PDF

Author: Daniel Lednicer

Publisher: Wiley-Interscience

Published: 1998-11-18

Total Pages: 0

ISBN-13: 9780471333708

DOWNLOAD EBOOK →

Updated every five years, the series represents the optimal compromise between currency and a sufficient body of material for cohesive and comprehensive treatment in a monograph. Provides a quick yet thorough overview of the synthetic routines that have been used to access specific classes of therapeutic agents. Materials are organized by chemical class, and syntheses are taken back to available starting materials. Discusses disease state, rational for method of drug therapy, biological activities of each compound and preparation. Coverage also includes those generic pharmaceutical compounds not accorded clinical status. A glossary defines biological terms.

The Organic Chemistry of Drug Synthesis, Volume 7

The Organic Chemistry of Drug Synthesis, Volume 7 PDF

Author: Daniel Lednicer

Publisher: John Wiley & Sons

Published: 2007-12-14

Total Pages: 288

ISBN-13: 0470180668

DOWNLOAD EBOOK →

The classic reference on the synthesis of medicinal agents -- now completely updated The seventh volume in the definitive series that provides a quick yet thorough overview of the synthetic routes used to access specific classesof therapeutic agents, this volume covers approximately 220 new non-proprietary drug entities introduced since the publication of Volume 6. Many of these compounds represent novel structural types firstidentified by sophisticated new cell-based assays. Specifically, a significant number of new antineoplastic and antiviral agents are covered. As in the previous volumes, materials are organized by chemical class and syntheses originate with available starting materials. Organized to make the information accessible, this resource covers disease state, rationale for method of drug therapy, and the biological activities of each compound and preparation. The Organic Chemistry of Drug Synthesis, Volume 7 is a hands-on reference for medicinal and organic chemists, and a great resource for graduate and advanced undergraduate students in organic and medicinal chemistry.

The Organic Chemistry of Drug Synthesis

The Organic Chemistry of Drug Synthesis PDF

Author: Daniel Lednicer

Publisher: Wiley-Interscience

Published: 1977

Total Pages: 272

ISBN-13:

DOWNLOAD EBOOK →

The Organic Chemistry of Drug Synthesis, Volume 6 covers the literature on the synthesis of medicinal agents from 1994 to 1998. This well-received series meets the needs of practitioners in the field who seek a quick overview of the synthetic routes that have been used to access specific classes of therapeutic agents. While most books on medicinal chemistry are organized on the basis of therapeutic or biochemical classes, materials in this series are arranged and discussed in terms of chemical structure. Thus, the preparation and detailed organic chemistry of the classes are presented in a unified way. Only drugs that have been granted a U.S. Adopted Name are included in this series. Synthetic organic, pharmaceutical, medicinal, and heterocyclic chemists will find this series an invaluable resource for their research in the synthetic chemistry of drug development.

The Organic Chemistry of Drug Synthesis, 4 Volume Set

The Organic Chemistry of Drug Synthesis, 4 Volume Set PDF

Author: Daniel Lednicer

Publisher: Wiley-Interscience

Published: 1991-01-16

Total Pages: 0

ISBN-13: 9780471531760

DOWNLOAD EBOOK →

Updated every five years, the series represents the optimal compromise between currency and a sufficient body of material for cohesive and comprehensive treatment in a monograph. Provides a quick yet thorough overview of the synthetic routines that have been used to access specific classes of therapeutic agents. Materials are organized by chemical class, and syntheses are taken back to available starting materials. Discusses disease state, rational for method of drug therapy, biological activities of each compound and preparation. Coverage also includes those generic pharmaceutical compounds not accorded clinical status. A glossary defines biological terms.

Drug Synthesis Book Set

Drug Synthesis Book Set PDF

Author: Jie Jack Li

Publisher: John Wiley & Sons

Published: 2015-11-23

Total Pages: 0

ISBN-13: 9781119185659

DOWNLOAD EBOOK →

This set presents the authoritative and acclaimed Drug Synthesis books edited by Jie Jack Li and Douglas Johnson: Contemporary Drug Synthesis, The Art of Drug Synthesis, Modern Drug Synthesis, and Innovative Drug Synthesis. This book set will be enormously useful to pharmaceutical industry labs, research scientists in lead optimization and process development, and graduate students and courses in organic chemistry, synthetic organic chemistry, heterocyclic chemistry, medicinal chemistry, and drug synthesis courses.

Strategies for Organic Drug Synthesis and Design

Strategies for Organic Drug Synthesis and Design PDF

Author: Daniel Lednicer

Publisher: John Wiley & Sons

Published: 2009-03-04

Total Pages: 700

ISBN-13: 9780470399590

DOWNLOAD EBOOK →

This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1st edition include synthesis of enantiomerically pure isomers, novel chemical methodologies, and new pharmaceutical agents targeted at novel biological endpoints. Written by an experienced successful author, this book meets the needs of a growing community of researchers in pharmaceutical R &D, as well as medical professionals, by providing a useful guide for designing and synthesizing pharmaceutical agents. Additionally, it is a useful text for medicinal chemistry students.

The Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action PDF

Author: Richard B. Silverman

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 650

ISBN-13: 0080513379

DOWNLOAD EBOOK →

Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization

An Introduction to Drug Synthesis

An Introduction to Drug Synthesis PDF

Author: Graham L. Patrick

Publisher: Oxford University Press, USA

Published: 2015

Total Pages: 587

ISBN-13: 0198708432

DOWNLOAD EBOOK →

'Introduction to Drug Synthesis' explores the central role played by organic synthesis in the process of drug design and development - from the generation of novel drug structures to the improved efficiency of large scale synthesis.

The Art of Drug Synthesis

The Art of Drug Synthesis PDF

Author: Douglas S. Johnson

Publisher: John Wiley & Sons

Published: 2013-02-26

Total Pages: 295

ISBN-13: 111867846X

DOWNLOAD EBOOK →

The Art of Drug Synthesis illustrates how chemistry, biology, pharmacokinetics, and a host of other disciplines come together to produce successful medicines. The authors have compiled a collection of 21 representative categories of drugs, from which they have selected as examples many of the best-selling drugs on the market today. An introduction to each drug is provided, as well as background to the biology, pharmacology, pharmacokinetics, and drug metabolism, followed by a detailed account of the drug synthesis. Edited by prominent scientists working in drug discovery for Pfizer Meets the needs of a growing community of researchers in pharmaceutical R&D Provides a useful guide for practicing pharmaceutical scientists as well as a text for medicinal chemistry students An excellent follow-up to the very successful first book by these editors, Contemporary Drug Synthesis, but with all new therapeutic categories and drugs discussed.

Organic Chemistry

Organic Chemistry PDF

Author: Robert J. Ouellette

Publisher: Elsevier

Published: 2014-06-06

Total Pages: 1240

ISBN-13: 0128010827

DOWNLOAD EBOOK →

Organic Chemistry provides a comprehensive discussion of the basic principles of organic chemistry in their relation to a host of other fields in both physical and biological sciences. This book is written based on the premise that there are no shortcuts in organic chemistry, and that understanding and mastery cannot be achieved without devoting adequate time and attention to the theories and concepts of the discipline. It lays emphasis on connecting the basic principles of organic chemistry to real world challenges that require analysis, not just recall. This text covers topics ranging from structure and bonding in organic compounds to functional groups and their properties; identification of functional groups by infrared spectroscopy; organic reaction mechanisms; structures and reactions of alkanes and cycloalkanes; nucleophilic substitution and elimination reactions; conjugated alkenes and allylic systems; electrophilic aromatic substitution; carboxylic acids; and synthetic polymers. Throughout the book, principles logically evolve from one to the next, from the simplest to the most complex examples, with abundant connections between the text and real world applications. There are extensive examples of biological relevance, along with a chapter on organometallic chemistry not found in other standard references. This book will be of interest to chemists, life scientists, food scientists, pharmacists, and students in the physical and life sciences. Contains extensive examples of biological relevance Includes an important chapter on organometallic chemistry not found in other standard references Extended, illustrated glossary Appendices on thermodynamics, kinetics, and transition state theory