The Molecular Biology and Pathology of Elastic Tissues

The Molecular Biology and Pathology of Elastic Tissues PDF

Author: Derek J. Chadwick

Publisher: John Wiley & Sons

Published: 2008-04-30

Total Pages: 374

ISBN-13: 0470514787

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Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and pathology of elastin at the molecular level. Topics include the structure, ultrastructure and function of elastin; elastin regulation; elastin's role in aging, lung development and disease and atherosclerosis; as well as related aspects of pharmacology and nutrition.

Connective Tissue Disease

Connective Tissue Disease PDF

Author: Jouni Uitto

Publisher: CRC Press

Published: 2021-07-29

Total Pages: 576

ISBN-13: 1000447227

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This book is a collection of works that canvass many of the recent developments in various areas of connective tissue research. It focuses on the structure of the components, molecular organization and pathology of the extracellular matrix.

Histology and Cell Biology: An Introduction to Pathology E-Book

Histology and Cell Biology: An Introduction to Pathology E-Book PDF

Author: Abraham L Kierszenbaum

Publisher: Elsevier Health Sciences

Published: 2011-04-12

Total Pages: 719

ISBN-13: 0323085881

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Histology and Cell Biology: An Introduction to Pathology uses a wealth of vivid, full-color images to help you master histology and cell biology. Dr. Abraham L. Kierszenbaum presents an integrated approach that correlates normal histology with cellular and molecular biology, pathology, and clinical medicine throughout the text. A unique pictorial approach—through illustrative diagrams, photomicrographs, and pathology photographs—paired with bolded words, key clinical terms in red, and clinical boxes and "Essential Concepts" boxes that summarize important facts give you everything you need to prepare for your course exams as well as the USMLE Step 1. Access to studentconsult.com, with USMLE-style multiple-choice review questions, downloadable images, and online only references. Easily find and cross-reference information through a detailed table of contents that highlights clinical examples in red. Review material quickly using pedagogical features, such as Essential Concept boxes, bolded words, and key clinical terms marked in red, that emphasize key details and reinforce your learning. Integrate cell biology and histology with pathology thanks to vivid descriptive illustrations that compare micrographs with diagrams and pathological images. Apply the latest developments in pathology through updated text and new illustrations that emphasize appropriate correlations. Expand your understanding of clinical applications with additional clinical case boxes that focus on applying cell and molecular biology to clinical conditions. Effectively review concepts and reinforce your learning using new Concept Map flow charts that provide a framework to illustrate the integration of cell-tissue-structure-function within a clinical-pathology context.

Elastin and Elastic Tissue

Elastin and Elastic Tissue PDF

Author: L. Sandberg

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 762

ISBN-13: 1468490931

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Although elastin was first identified and purifled in 1840, relatively few, major advances to determine its structure and function occurred between then and 1970. This was pointed out by Carl Franzblau in his recent review (1). This sad state of affairs does not detract, however, from the importance of contributions made during the last 50 years; many of these are referred to in the various chapters that comprise this monograph. I would be remiss not to emphasize the pioneering work of S. M. Partridge, who, in 1955, reported on a technique to obtain virtually pure elastin. It was, indeed, a privilege to have the participation of Dr. Partridge in the First International Conference on Elastin, the proceedings of which constitute this volume. In 1974, the Division of Lung Diseases of the National Heart, Lung, and Blood Institute initiated a targeted research program on "Isolation and Purification of Lung Elastin". It was an asset to the program that it attracted eminent scientists who, in effect, stimulated a new wave of interest and activity in this neglected area of research. This resurgence of interest may have been due to the challenge of working with a tissue that presented difficulties which had in the past discour aged investigators. It soon became apparent that the research program initiated by the Division of Lung Diseases was attracting much interest and that many significant contributions would result from it.

Histology and Cell Biology

Histology and Cell Biology PDF

Author: E. Robert Burns

Publisher:

Published: 2007

Total Pages: 340

ISBN-13:

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Get the most from your study time...and experience a realistic USMLE simulation! These new additions to the Rapid Review Series-highly rated in the First Aid rankings-make it easy for you to master all of the basic science material covered on the USMLE Step 1 Exam. Each title focuses on a particular basic science subject, providing an at-a-glance, outline-format review of all the information you need to know. A user-friendly 2-color layout, Hi-Yield Margin Notes, and Key Points make studying easy. 100 high-quality USMLE-style review questions inside each book allow you to practice for the USMLE, and include a full rationale that lets you know why every possible answer is right or wrong. Another 250 USMLE-style questions for each title are available at www.studentconsult.com-mirroring the look and feel of the actual exam, and providing detailed feedback on which areas you may need to study more.

Biochemistry of Collagens, Laminins and Elastin

Biochemistry of Collagens, Laminins and Elastin PDF

Author: Morten Karsdal

Publisher: Academic Press

Published: 2016-07-29

Total Pages: 272

ISBN-13: 0128098996

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Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers provides a comprehensive introduction to collagen and structural proteins. Type I collagen is one of the most abundant molecules in the body, playing essential roles in different tissues, particularly bone and skin. A key aspect of type I collagen is its post-translational modifications which are essential for correct synthesis and structural integrity of collagens, for tissue-specific functionality, as well as for application as biomarkers of different pathologies. This volume summarizes current data on key structural proteins (collagens, laminins and elastin), reviews how these molecules affect pathologies, and describes selected modifications of proteins that result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the ECM harbor cryptic signaling functions that may be viewed as endocrine functions. Additionally, it highlights how this knowledge can be exploited to modulate fibrotic disease. Provides a comprehensive introduction to collagen and structural proteins Provides insight into emerging analytical technologies that can detect biomarkers of extracellular matrix degradation Includes a chapter dedicated to the biomarkers of structural proteins Contains insights into the biochemical interactions and changes to structural composition of proteins in disease states

Connective Tissue

Connective Tissue PDF

Author: Nikolay Petrovich Omelyanenko

Publisher: CRC Press

Published: 2016-04-19

Total Pages: 630

ISBN-13: 1482203596

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Connective tissue is a multicomponent, polyfunctional complex of cells and extracellular matrix that serves as a framework for all organs, combining to form a unified organism. It is a structure responsible for numerous vital functions such as tissue-organ integration, morphogenesis, homeostasis maintenance, biomechanical support, and more. The reg

Musculoskeletal Disorders and the Workplace

Musculoskeletal Disorders and the Workplace PDF

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2001-06-24

Total Pages: 511

ISBN-13: 0309072840

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Every year workers' low-back, hand, and arm problems lead to time away from jobs and reduce the nation's economic productivity. The connection of these problems to workplace activities-from carrying boxes to lifting patients to pounding computer keyboards-is the subject of major disagreements among workers, employers, advocacy groups, and researchers. Musculoskeletal Disorders and the Workplace examines the scientific basis for connecting musculoskeletal disorders with the workplace, considering people, job tasks, and work environments. A multidisciplinary panel draws conclusions about the likelihood of causal links and the effectiveness of various intervention strategies. The panel also offers recommendations for what actions can be considered on the basis of current information and for closing information gaps. This book presents the latest information on the prevalence, incidence, and costs of musculoskeletal disorders and identifies factors that influence injury reporting. It reviews the broad scope of evidence: epidemiological studies of physical and psychosocial variables, basic biology, biomechanics, and physical and behavioral responses to stress. Given the magnitude of the problem-approximately 1 million people miss some work each year-and the current trends in workplace practices, this volume will be a must for advocates for workplace health, policy makers, employers, employees, medical professionals, engineers, lawyers, and labor officials.

Arterial Stiffness in Hypertension

Arterial Stiffness in Hypertension PDF

Author: Michel Safar

Publisher: Elsevier Health Sciences

Published: 2006-04-21

Total Pages: 618

ISBN-13: 0444517588

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Main headings: I. Basic concepts of pulsatile arterial hemodynamics. - II. Pathophysiological mechanisms. - III. Arterial stiffness, wave reflections, cardiovascular risk and end-organ damage. - IV. Clinical aspects of arterial stiffness and wave reflections. - V. Therapeutic aspects of arterial stiffness and wave reflections.