Author: Liisa Ahtee
Publisher: Elsevier
Published: 2013-10-22
Total Pages: 325
ISBN-13: 148315775X
DOWNLOAD EBOOK →Neurotransmission is the second volume of the proceedings of the Sixth International Congress of Pharmacology, organized by the Finnish Pharmacological Society and held in Helsinki, Finland, on July 20-25, 1975. The papers focus on the developments in neurotransmission and cover topics ranging from novel transmitter substances and extraneuronal uptake of catecholamines to axonal transport mechanisms and nerve growth factor. This volume has 28 chapters divided into five sections. After discussing the possible functional role of certain tryptaminergic pathways, this book turns its attention to the metabolism of endogenous noradrenaline, with emphasis on the role of 3,4-dihydroxyphenylglycol (DOPEG). The chapters that follow focus on amino acids as possible neurotransmitters, including histamine and glutamate. This text discusses as well the mechanisms underlying extraneuronal amine uptake and metabolism in the salivary glands; the effect of oxytetracycline on the responses of various tissue preparations to added noradrenaline and to field stimulation; and how axoplasmic transport is blocked by pharmacological agents. This book will be of interest to scientists representing all the major areas of pharmacology, including clinical pharmacology and toxicology, as well as interdisciplinary areas related to physiology, biochemistry, and endocrinology. Many of the topics will also appeal to internists, psychiatrists, neurologists, and anaesthesiologists.
Author: S.Z. Langer
Publisher: Elsevier
Published: 2013-10-22
Total Pages: 373
ISBN-13: 1483278220
DOWNLOAD EBOOK →Advances in the Biosciences, Volume 82: Presynaptic Receptors and Neuronal Transporters documents the proceedings of the Official Satellite Symposium to the IUPHAR 1990 Congress held in Rouen, France on June 26-29, 1990. The first part of this book deals with the extensive and still increasing list of presynaptic release-modulating auto and heteroreceptors, emphasizing the various subtypes of presynaptic receptors that are characterized by functional studies, both in vitro and in vivo, using a number of experimental approaches. The next chapters are devoted to the molecular pharmacology of presynaptic receptors, of which can interfere with G proteins and modify the activity of adenylate cyclase, guanylate cyclase, or protein kinase C. The purification and molecular biology of transporter systems, including cloning and sequencing of the neuronal sodium-ion coupled GABA transporter are also discussed. This compilation concludes with insights on the function of presynaptic receptors and neuronal transporters both in the periphery and in the CNS, as well as their ubiquitous locations and physiological roles. This publication is a good reference for students and individuals researching on the presynaptic autoreceptors and neurotransmitters.
Author: Ernst Jucker
Publisher: Springer Science & Business Media
Published: 1998
Total Pages: 384
ISBN-13: 9783764358211
DOWNLOAD EBOOK →Progress in Drug Research is a prestigious book series (founded in 1959) which provides extensive expert-written reviews on a wide spectrum of highly topical areas in current pharmaceutical and pharmalogical research. Each volume contains fully cross-referencing indexes which link the volumes together, forming a virtually encyclopaedic work. The series thus serves as an important, time-saving source of information for researchers concerned with drug research and all those who need to keep abreast of the many recent developments in the quest for new and better medicines. Volume 50 in the series includes: P.N. Kaul: Drug discovery: Past, present and future M. Rohmer: Isoprenoid biosynthesis via the mevalonate -- independent route, a novel target for antibacterial drugs G. Edwards and A.H. Weston: Endothelium, -derived hyperpolarizing factor -- a critical appraisal R.W. Rockhold: Glutamatic involvement in psychomotor stimulant action J.M. Colacino and K.A. Staschke: The identification and development of antiviral agents for the treatment of chronic hepatitis B virus infection T.D. Johnson: Polyamines and cerebral ischemia
Author:
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 585
ISBN-13: 3642466257
DOWNLOAD EBOOK →Catecholamines are important transmitter substances in the autonomic and central nervous systems. These two volumes provide a comprehensive presentation of the state-of-the-art of catecholamine research and development in the past 15 years. The volumes present in-depth reviews of topical areas of catecholamine research in which substantial progress has been made and which are of current interest to various theoretical and clinical disciplines. Each topic has been dealt with by an established expert. Clinical subjects of relevant importance are included. Catecholamines are of interest in pharmacology, physiology, biochemistry, as well as in neurology, psychiatry, internal medicine (cardiology, hypertension, asthma), ophthalmology and anesthesiology.
Author: Ruth Heidelberger
Publisher: Academic Press
Published: 2009-01-27
Total Pages: 654
ISBN-13: 0080920837
DOWNLOAD EBOOK →An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. From Molecules to Networks provides the solid foundation of the morphologic, biochemical, and biophysical properties of nerve cells. All chapters have been thoroughly revised for this second edition to reflect the significant advances of the past 5 years. The new edition expands on the network aspects of cellular neurobiology by adding a new chapter, Information Processing in Neural Networks, and on the relation of cell biological processes to various neurological diseases. The new concluding chapter illustrates how the great strides in understanding the biochemical and biophysical properties of nerve cells have led to fundamental insights into important aspects of neurodegenerative disease. Written and edited by leading experts in the field, the second edition completely and comprehensively updates all chapters of this unique textbook Discusses emerging new understanding of non-classical molecules that affect neuronal signaling Full colour, professional graphics throughout Includes two new chapters: Information Processing in Neural Networks - describes the principles of operation of neural networks and the key circuit motifs that are common to many networks in the nervous system. Molecular and Cellular Mechanisms of Neurodegenerative Disease - introduces the progress made in the last 20 years in elucidating the cellular and molecular mechanisms underlying brain disorders, including Amyotrophic Lateral Sclerosis (ALS), Parkinson disease, and Alzheimer’s disease
Author: Harald Sitte
Publisher: Springer Science & Business Media
Published: 2006-08-02
Total Pages: 549
ISBN-13: 3540297847
DOWNLOAD EBOOK →This book is a representative survey of the current status of the structure, function, regulation and molecular pharmacology of Neurotransmitter Transporters. It provides an overview of insights generated in the past five years. The volume serves as a useful compendium of current concepts and an inspiring starting point. It is a source for students interested in this emerging field as well as for experienced scientists looking for an update.
Author: Lee E. Eiden
Publisher: Academic Press
Published: 2013-09-17
Total Pages: 500
ISBN-13: 012411539X
DOWNLOAD EBOOK →This new volume of Advances in Pharmacology presents catecholamine symposium proceedings. Chapters cover such topics as cellular dynamics of catecholamine release and re-uptake, catecholamines in mood regulation and imaging catecholamine transporters. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike. Presents catecholamine symposium proceedings Chapters cover a variety of topics such as cellular dynamics of catecholamine release and re-uptake, catecholamines in mood regulation and imaging catecholamine transporters With the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike
Author: Peter Riederer
Publisher: Springer Science & Business Media
Published: 2013-03-13
Total Pages: 467
ISBN-13: 3709191130
DOWNLOAD EBOOK →The Amine Oxidase Workshop was the brain child of Brian Callingham and Keith Tipton. The present book is the proceedings of the fourth in the series and in the past we have dedicated our meeting to individuals who have made significant fundamental contributions to the biochemistry, physiology and pharmacology of this interesting group of enzymes. The present meeting is not an exception because we have gathered here in Wtirzburg to honour an individual whose outstanding work on the autonomic pharmacology has span ned more than 30 years and whose contribution has made a vast impact in our understanding of the kinetic relationship between amine metabolism (that uptake and enzymatic inactivation) and adrenergic neurotransmission. We speak of course of Professor Ullrich Trendelenburg, or Ulli as he likes to be known. Like the amine oxidases, he has a unique place in Pharmacology. Professor Trendelenburg was born on the eve of the new year of 1922 in the city of Rostock in northern Germany, where his father was Professor of Pharmacology at the Faculty of Medicine of Rostock. His father accepted the offer to take over the corresponding chair in Freiburg im Breisgrau (in Southern Germany). As the youngest of four children, Ulli grew up mainly in the garden of the department, in the animal quarters and in the workshop. Of the various coworkers of his father, one he liked especially was Otto Krayer, the young pharmacologist.