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The Leishmaniases: Old Neglected Tropical Diseases

Author: Fabrizio Bruschi

Publisher: Springer

Published: 2018-01-12

Total Pages: 245

ISBN-13: 3319723863

Out of the 20 neglected tropical diseases (NTDs) prioritized by the World Health Organization, the leishmaniases rank in the top 3 among those caused by protozoa. The purpose of this book is to provide the reader with a comprehensive and updated overview of all the aspects of leishmaniasis with a worldwide perspective – authors of many chapters include eminent scientists from both the Old and New Worlds. The chapters cover a wide range of topics, classically organized into biology and epidemiology, followed by clinical and control aspects. Following an introductory chapter intended to take the reader into the leishmaniasis complexity, a chapter on Leishmania taxonomy reports on the most recent advances in molecular and phylogenetic data. Parasite biology is then described in detail by means of two separate chapters devoted to phlebotomine vectors and reservoir hosts, respectively. The medical part of the book begins with a chapter on basic immunology and immunopathology associated with Leishmania infection, followed by a classical chapter on clinical aspects of different disease entities. The complexity of disease case management is presented by means of 3 chapters, respectively on diagnosis, treatment of visceral forms and treatment of tegumentary forms. Finally, the last chapter deals with the available approaches to control leishmaniasis and related public health issues.

The Leishmaniases: Old Neglected Tropical Diseases

Author: Fabrizio Bruschi

Publisher: Springer

Published: 2018-01-25

Total Pages: 0

ISBN-13: 9783319723853

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Neglected Tropical Diseases - Sub-Saharan Africa

Author: John Gyapong

Publisher: Springer

Published: 2016-01-13

Total Pages: 414

ISBN-13: 3319254715

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This book provides an overview on the major neglected tropical diseases (NTDs) occurring in Sub-Saharan Africa, such as Leishmaniasis, Buruli Ulcer and Schistosomiasis. In well-structured chapters epidemiology and biology of these parasitic diseases will be discussed in detail. Further, diagnostics and therapeutic approaches as well as prevention strategies will be reviewed. The book will be of interest to basic researchers and clinicians engaged in infectious disease, tropical medicine, and parasitology, and a must-have for scientists specialized in the characteristics of the Sub-Saharan region.

Investing to Overcome the Global Impact of Neglected Tropical Diseases

Author: World Health Organization

Publisher: World Health Organization

Published: 2015-08-05

Total Pages: 211

ISBN-13: 9241564865

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"The presence, or absence, of neglected tropical diseases (NTDs) can be seen as a proxy for poverty and for the success of interventions aimed at reducing poverty. Today, coverage of the public-health interventions recommended by the World Health Organization (WHO) against NTDs may be interpreted as a proxy for universal health coverage and shared prosperity - in short, a proxy for coverage against neglect. As the world's focus shifts from development to sustainable development, from poverty eradication to shared prosperity, and from disease-specific goals to universal health coverage, control of NTDs will assume an important role towards the target of achieving universal health coverage, including individual financial risk protection. Success in overcoming NTDs is a "litmus test" for universal health coverage against NTDs in endemic countries. The first WHO report on NTDs (2010) set the scene by presenting the evidence for how these interventions had produced results. The second report (2013) assessed the progress made in deploying them and detailed the obstacles to their implementation. This third report analyses for the first time the investments needed to achieve the scale up of implementation required to achieve the targets of the WHO Roadmap on NTDs and universal coverage against NTDs. INVESTING TO OVERCOME THE GLOBAL IMPACT OF NEGLECTED TROPICAL DISEASES presents an investment strategy for NTDs and analyses the specific investment case for prevention, control, elimination and eradication of 12 of the 17 NTDs. Such an analysis is justified following the adoption by the Sixty-sixth World Health Assembly in 2013 of resolution WHA6612 on neglected tropical diseases, which called for sufficient and predictable funding to achieve the Roadmap's targets and sustain control efforts. The report cautions, however, that it is wise investment and not investment alone that will yield success. The report registers progress and challenges and signals those that lie ahead. Climate change is expected to increase the spread of several vector-borne NTDs, notably dengue, transmission of which is directly influenced by temperature, rainfall, relative humidity and climate variability primarily through their effects on the vector. Investments in vector-borne diseases will avoid the potentially catastrophic expenditures associated with their control. The presence of NTDs will thereby signal an early warning system for climate-sensitive diseases. The ultimate goal is to deliver enhanced and equitable interventions to the most marginalized populations in the context of a changing public-health and investment landscape to ensure that all peoples affected by NTDs have an opportunity to lead healthier and wealthier lives."--Publisher's description.

The Epidemiology and Ecology of Leishmaniasis

Author: David Claborn

Publisher: BoD – Books on Demand

Published: 2017-03-01

Total Pages: 178

ISBN-13: 9535129716

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Leishmaniasis is a vector-borne, parasitic disease with tremendous variety in presentation, biology, and epidemiology. Any book on this disease must acknowledge the nearly impossible task of providing an exhaustive account of leishmaniasis simply because the epidemiology of the disease is so very complex. This book addresses some of this variety with chapters on the epidemiology of leishmaniasis in North Africa, Central America, and South America. The purpose of the book is not to specifically address diagnosis and treatment of the disease, but rather to provide a sample of the differing epidemiologies of leishmaniasis that occur due to variations in local habitats; the presence of different vectors, reservoirs, and agents; and the wide variety of cultures in which this disease occurs.

One Health and Neglected Tropical Diseases

Author: Claire J Standley

Publisher: Mdpi AG

Published: 2021-08-18

Total Pages: 160

ISBN-13: 9783036502861

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"One Health" is defined as an approach to achieve better health outcomes for humans, animals, and the environment through collaborative and interdisciplinary efforts. The One Health framework is increasingly being applied to the management, control, and even elimination of neglected tropical diseases (NTDs), a set of infectious diseases that, collectively, affect more than one billion people across almost 150 countries. NTDs are some of the most common infections in the world; they cause substantial morbidity and mortality, particularly in regions with little access to medical care and other resources. Although there is increasing recognition of the major public health threat presented by NTDs, the ecological complexities of their transmission continue to pose challenges for their control and elimination. Some NTDs are zoonotic, meaning that they can be transmitted between humans and animals and, as such, present obstacles for public health and veterinary services in addition to concerns for wildlife conservation. Vector-borne NTDs necessitate measures that integrate consideration of the environment into public health strategies in order to sustainably reduce disease transmission. This book presents a collection of papers that explore various aspects of how the One Health concept is being applied to NTD control around the world, from genomics and diagnostic tools to improved surveillance and disease management. Encompassing research from Central America, the Caribbean, Asia, and sub-Saharan Africa, the collection emphasizes the diversity of NTDs as well as the critical importance of multisectoral collaboration for their control and elimination.

Imported Infectious Diseases

Author: Fernando Cobo

Publisher: Elsevier

Published: 2014-10-07

Total Pages: 299

ISBN-13: 1908818735

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The increase of immigrant population in developed countries (mainly in Europe and North America) together with an important increase of international travel worldwide are the two most important causes that have contributed to the introduction and diagnosis of imported/tropical infectious diseases in these countries. These factors have had an important impact in developed countries in both social and economic aspects. Imported Infectious Diseases focuses not only on describing the infections, but also in evaluating the current epidemiology, the economic and social impact and the possibility to apply immunization measures and vaccines. The main purpose of this book is to give an overview of the current most important and frequent imported infectious diseases in developed countries. The first chapter informs about the medical services that are being offered to the immigrants in the main developed countries depending on the legal situation. Following chapters describe the main surveillance systems for these kinds of diseases, mainly in Europe and North America. Finally, remaining chapters contain sections on epidemiology, pathogenesis, clinical features, diagnosis, treatment and prevention.

Tropical Dermatology

Author: Roberto Arenas

Publisher: CRC Press

Published: 2001-01-01

Total Pages: 358

ISBN-13: 1498712754

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Tropical diseases are not merely a group of nosologic diseases indigenous to the intertropical zone. Many are diseases of poor public health originating from poverty, ignorance, and population upheaval. Tropical dermatoses represent a public health problem in 127 countries with a population of 3 billion people who do not have access to health care.

Parasitology and Microbiology Research

Author: Gilberto Antonio Bastidas Pacheco

Publisher: BoD – Books on Demand

Published: 2020-06-17

Total Pages: 376

ISBN-13: 1789859018

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The study of both unicellular and multicellular living beings and the diseases they produce from a biological point of view requires constant review of their relationship with their host and environment, given their indisputable sanitary importance. In this sense, in parasitology and microbiology, updated and concise information on life cycle, taxonomic classification, clinical manifestations, diagnosis, treatment, epidemiological behavior, and control measures is of vital importance. This is what we pursue with this book. The approach to parasitology and microbiology and the research that is carried out on it is unquestionable because the associations between life forms have been present from the very beginning of life.Research in parasitology and microbiology is necessary and indispensable for controlling diseases that affect much of the world with serious economic and social consequences. The challenge is to promote research to keep these diseases at bay. This book shows what has been done up to now and what can be done in the future to combat infectious diseases.

Leishmaniases as Re-emerging Diseases

Author: Farhat Afrin

Publisher: BoD – Books on Demand

Published: 2018-10-10

Total Pages: 234

ISBN-13: 1789841011

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Leishmania parasites plague the mammalian host causing high morbidity and mortality. The parasites persist in the hostile milieu, crippling its defensive arsenal. In the face of mounting resistance to an antiquated drug arsenal, new approaches are urgently desired to keep the infection at bay. Furthermore, to strengthen the leishmaniasis elimination drive, particular emphasis has to be laid on identification of new targets and vaccination strategies. This book gives a brief glimpse of the epidemiology of leishmaniasis, immune evasion, vaccination, and therapeutic modalities that may work by untangling the immunological cross-wires of pathogenic cross-talk. The Conventional treatment and its drawbacks, the prospects of phytotherapy and nanomedicines, are also discussed. The identification of drug targets with the aim of designing inhibitors is also exemplified.