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Mesenchymal Stem Cell in Veterinary Sciences
Author: Mudasir Bashir Gugjoo
Publisher: Springer Nature
Published: 2020-11-09
Total Pages: 347
ISBN-13: 9811560374
DOWNLOAD EBOOK →This book focuses on mesenchymal stem cells (MSCs) of animal origin, including their isolation, characterization, and clinical applications. After briefly discussing the historical development of the field of stem cell research, it describes the basic properties and nature of stem cells particularly in relation to MSCs. In turn, it reviews materials and methods used to isolate MSCs from various sources, culture expansion, characterization and long-term storage. It also explores the therapeutic efficacy, immunomodulation and anti-inflammatory, and differentiation properties of MSCs. Importantly, the book discusses the applications of genetic engineering to enhance the efficacy and potential of MSCs in regenerative medicine. The book largely addresses the potential applications of mesenchymal stem cells in therapies for important species of domesticated animals including sheep, goats, cattle, buffalo, cats, dogs and horses. Finally, the book presents an abridgement of challenges and future prospects of stem cell research and application in medicine, in general and veterinary sciences, in particular.
Mesenchymal Stem Cells
Author: Phuc Van Pham
Publisher: BoD – Books on Demand
Published: 2017-11-29
Total Pages: 302
ISBN-13: 9535136151
DOWNLOAD EBOOK →Mesenchymal Stem Cells: Isolation, Characterization, and Applications thoroughly presents the isolation, characterization, and some applications of mesenchymal stem cells in the clinic. The book has two parts: "Isolation and Characterization" and "Clinical Perspectives and Applications." In Part I, the subsequent chapters introduce some techniques in isolation, characterization, and purification of mesenchymal stem cells in different tissues. In Part II, some applications of mesenchymal stem cells in the popular diseases, which include cartilage regeneration, spinal cord injury, and osteoarthritis, are discussed. This book provides a succinct yet comprehensive overview of mesenchymal stem cells for advanced students, graduate students, and researchers.
Adipose-Derived Stem Cells
Author: Jeffrey M. Gimble
Publisher: Humana Press
Published: 2011-08-24
Total Pages: 474
ISBN-13: 9781617379611
DOWNLOAD EBOOK →During the past decade, a wide range of scientific disciplines have adopted the use of adipose-derived stem/stromal cells (ASCs) as an important tool for research and discovery. In Adipose-Derived Stem Cells: Methods and Protocols, experts from the field, including members of the esteemed International Federation of Adipose Therapeutics and Science (IFATS), provide defined and established protocols in order to further codify the utilization of these powerful and accessible cells. With chapters organized around approaches spanning the discovery, pre-clinical, and clinical processes, much of the emphasis is placed on human ASC, while additional techniques involving small and large animal species are included. As a volume in the highly successful Methods in Molecular BiologyTM series, the detailed contributions include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Adipose-Derived Stem Cells: Methods and Protocols serves as a vital reference text for experienced researchers as well as new students on the path to further exploring the incredible potential of ASCs.
Mesenchymal Stem Cell Therapy
Author: Lucas G. Chase
Publisher: Springer Science & Business Media
Published: 2012-12-12
Total Pages: 458
ISBN-13: 1627032002
DOWNLOAD EBOOK →Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.
Mesenchymal Stromal Cells: Preclinical and Clinical Challenges
Author: Joan Oliva
Publisher: Frontiers Media SA
Published: 2022-08-12
Total Pages: 336
ISBN-13: 2889767701
DOWNLOAD EBOOK →Veterinary Surgery: Small Animal Expert Consult - E-BOOK
Author: Spencer A. Johnston
Publisher: Elsevier Health Sciences
Published: 2017-06-14
Total Pages: 2600
ISBN-13: 032332049X
DOWNLOAD EBOOK →Focus on the "how" and "why" of medical/surgical conditions — the critical issues that lead to successful outcomes for your patients — with Veterinary Surgery: Small Animal, Second Edition. This two-volume full-color resource offers an authoritative, comprehensive review of disease processes, a thorough evaluation of basic clinical science information, and in-depth discussion of advanced surgeries. With an updated Expert Consult website you can access anytime and detailed coverage of surgical procedures, it is the definitive reference for surgical specialists, practicing veterinarians, and residents. Expert Consult website offers access to the entire text online, plus references linked to original abstracts on PubMed. Comprehensive coverage includes surgical biology, surgical methods and perioperative care, neurosurgery, and orthopedics in Volume One, and all soft tissue surgery organized by body system in Volume Two. Extensive references to published studies available on Expert Consult show the factual basis for the material. Strong blend of clinical and basic science information facilitates a clear understanding of clinical issues surrounding operative situations. Highly recognized contributing authors create chapters from their own experience and knowledge base, providing the most authoritative, current information available. Coverage of anatomy, physiology, and pathophysiology in chapters on specific organs includes information critical to operative procedures and patient management. In-depth chapters on anesthesia, surgical oncology, tumors of the spine, and musculoskeletal neoplasia provide valuable resources for practicing surgeons, especially in the area of cancer treatment. Preoperative considerations and surgical implications for surgical procedures help surgeons make decisions about treatment approaches. NEW and UPDATED! Expert Consult website with print text plus complete online access to the book’s contents, so you can use it anytime — anywhere. EXPANDED! Coverage of interventional radiology techniques in Volume Two (soft tissue volume) to provide cutting-edge information on contemporary imaging modalities that gain access to different structures of the patient’s body for diagnostic and therapeutic reasons. NEW and UPDATED! Expanded coverage of coaptation devices and small animal prosthetics clearly explains how they are used in a variety of clinical situations. EXPANDED! Principles of minimally invasive plate treatment added to Volume One (orthopedic volume) to show how these advancements maximize healing and protect the patient while meeting the surgeon’s goals in using fracture fixation.
Animal Models for Stem Cell Therapy
Author: Bruno Christ
Publisher: Humana Press
Published: 2014-09-01
Total Pages: 0
ISBN-13: 9781493914524
DOWNLOAD EBOOK →In Animal Models for Stem Cell Therapy: Methods and Protocols, expert researchers in the field detail disease models of hepatic, cardiovascular, neurological diseases, connective and contractile tissue. Chapters focus on a wide range of diseases and application of different kinds of stem cells and reprogrammed tissue cells (iPS). Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Animal Models for Stem Cell Therapy: Methods and Protocols, covers interest of basic scientists and clinicians to assess the biological as well as the therapeutic potential of stem cell therapy.
Rising Stars in Veterinary Regenerative Medicine: 2022
Author: Janina Burk
Publisher: Frontiers Media SA
Published: 2023-12-18
Total Pages: 168
ISBN-13: 2832541240
DOWNLOAD EBOOK →Veterinary patients, from companion to farm animals, play a key role in our society and economy as members of families which provide leisure or sustenance. Therefore, their health and welfare are of utmost importance and should be supported by all means available. The field of regenerative medicine offers new opportunities to understand and treat diseases, with a growing interest to benefit animals not only as models but also as patients. The rapid expansion of the veterinary regenerative medicine field demands for continuous innovation. A big share of the affiliated research is contributed by dedicated young researchers willing to advance the standard of animal care.
Placenta
Author: Ornella Parolini
Publisher: CRC Press
Published: 2016-02-22
Total Pages: 296
ISBN-13: 1498700276
DOWNLOAD EBOOK →Long regarded as biological waste, the placenta is gaining momentum as a viable product for clinical use. Due to their unique properties, placental cells and derivatives show great promise in curing various diseases. Utilizing contributions from world-renowned experts, Placenta: The Tree of Life considers the therapeutic potential of these cells. It examines new stem cell–based strategies and highlights recent studies that advance the range of treatment for a number of illnesses. Emphasizing the potential research and therapeutic use of stem cells, the book discusses the development, structure, and functions of the human placenta. It introduces overall aspects of the immune system, explains some of the immune mechanisms during pregnancy, and shows the role of the placenta in these mechanisms. Current scientific research is presented that focuses on the mechanisms of action underlying the therapeutic benefit of cells isolated from different placental regions. An exhaustive examination, this pivotal work: Considers how perinatal cells may represent an important source for cell therapy approaches in the near future, in both human and veterinary medicine Describes the clinical potential of placenta-derived cells in regenerative medicine—specifically in neurological disorders, metabolic liver diseases, inflammatory diseases, and autoimmune diseases Explains how cells isolated from different placental tissues share basic properties Placenta: The Tree of Life summarizes the advantages of perinatal tissue as a source of cells with therapeutic potential and is designed for use in the study of genetics, stem cell science, placental function, reproductive biology, regenerative medicine, and related fields.
