The Immune System

The Immune System PDF

Author: Paul Klenerman

Publisher: Oxford University Press

Published: 2017

Total Pages: 145

ISBN-13: 019875390X

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The immune system is central to human health and the focus of much medical research. Growing understanding of the immune system, and especially the creation of immune memory (long lasting protection), which can be harnessed in the design of vaccines, have been major breakthroughs in medicine. In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. In particular he focuses on the human immune system, considering how it evolved, the basic rules that govern its behavior, and the major health threats where it is important. The immune system comprises a series of organs, cells and chemical messengers which work together as a team to provide defence against infection. Klenerman discusses these components, the critical signals that trigger them and how they exert their protective effects, including so-called innate immune responses, which react very fast to infection, and adaptive immune responses, which have huge diversity and a capacity to recognize and defend against a massive array of micro-organisms. Klenerman also considers what happens when our immune systems fail to be activated effectively, leading to serious infections, problems with inherited diseases, and also HIV/AIDS. At the opposite extreme, as Klenerman shows, an over-exaggerated immune response leads to inflammatory diseases such as Multiple Sclerosis and Rheumatoid Arthritis, as well as allergy and asthma. Finally he looks at the Immune system v2.o - how immune therapies and vaccines can be advanced to protect us against the major diseases of the 21st century. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Viruses

Viruses PDF

Author: Dorothy H. Crawford

Publisher: Oxford University Press

Published: 2018

Total Pages: 177

ISBN-13: 0198811713

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Viruses are big news. From pandemics such as HIV, swine flu, and SARS, we are constantly being bombarded with information about new lethal infections. In this Very Short Introduction, Dorothy Crawford demonstrates from their discovery and the unravelling of their intricate structures, how clever these entities really are.

Plague: A Very Short Introduction

Plague: A Very Short Introduction PDF

Author: Paul Slack

Publisher: OUP Oxford

Published: 2012-03-22

Total Pages: 161

ISBN-13: 0191623962

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Throughout history plague has been the cause of many major catastrophes. It was responsible for the Black Death of 1348 and the Great Plague of London in 1665, and for devastating epidemics much earlier and much later, in the Mediterranean in the sixth century, and in China and India between the 1890s and 1920s. Today, it has become a metaphor for other epidemic disasters which appear to threaten us, but plague itself has never been eradicated. In this Very Short Introduction, Paul Slack explores the historical impact of plague over the centuries, looking at the ways in which it has been interpreted, and the powerful images it has left behind in art and literature. Examining what plague meant for those who suffered from it, and how governments began to fight against it, he demonstrates the impact plague has had on modern notions of public health and how it has shaped our history. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Microbiology: A Very Short Introduction

Microbiology: A Very Short Introduction PDF

Author: Nicholas P. Money

Publisher: OUP Oxford

Published: 2014-12-04

Total Pages: 144

ISBN-13: 0191503916

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In recent decades we have come to realize that the microbial world is hugely diverse, and can be found in the most extreme environments. Fungi, single-celled protists, bacteria, archaea, and the vast array of viruses and sub-viral particles far outnumber plants and animals. Microbes, we now know, play a critical role in ecosystems, in the chemistry of atmosphere and oceans, and within our bodies. The field of microbiology, armed with new techniques from molecular biology, is now one of the most vibrant in the life sciences. In this Very Short Introduction Nicholas P. Money explores not only the traditional methods of microscopy and laboratory culture but also the modern techniques of genetic detection and DNA sequencing, genomic analysis, and genetic manipulation. In turn he demonstrates how advances in microbiology have had a tremendous impact on the areas of medicine, agriculture, and biotechnology. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

The Cell: A Very Short Introduction

The Cell: A Very Short Introduction PDF

Author: Terence Allen

Publisher: OUP Oxford

Published: 2011-09-29

Total Pages: 160

ISBN-13: 0191620262

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All living things on Earth are composed of cells. A cell is the simplest unit of a self-contained living organism, and the vast majority of life on Earth consists of single-celled microbes, mostly bacteria. These consist of a simple 'prokaryotic' cell, with no nucleus. The bodies of more complex plants and animals consist of billions of 'eukaryotic' cells, of varying kinds, adapted to fill different roles - red blood cells, muscle cells, branched neurons. Each cell is an astonishingly complex chemical factory, the activities of which we have only begun to unravel in the past fifty years or so through modern techniques of microscopy, biochemistry, and molecular biology. In this Very Short Introduction, Terence Allen and Graham Cowling describe the nature of cells - their basic structure, their varying forms, their division, their differentiation from initially highly flexible stem cells, their signalling, and programmed death. Cells are the basic constituent of life, and understanding cells and how they work is central to all biology and medicine. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Pandemics

Pandemics PDF

Author: Christian W. McMillen

Publisher: Oxford University Press

Published: 2016

Total Pages: 172

ISBN-13: 0199340072

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Machine generated contents note: -- Introduction -- Chapter 1: Plague -- Chapter 2: Smallpox -- Chapter 3: Malaria -- Chapter 4: Cholera -- Chapter 5: Tuberculosis -- Chapter 6: Influenza -- Chapter 7: HIV/AIDS -- References -- Further Reading -- Index

How the Immune System Works

How the Immune System Works PDF

Author: Lauren M. Sompayrac

Publisher: John Wiley & Sons

Published: 2015-10-26

Total Pages: 160

ISBN-13: 1118997778

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How the Immune System Works has helped thousands of students understand what’s in their big, thick, immunology textbooks. In his book, Dr. Sompayrac cuts through the jargon and details to reveal, in simple language, the essence of this complex subject. In fifteen easy-to-read chapters, featuring the humorous style and engaging analogies developed by Dr. Sompayrac, How the Immune System Works explains how the immune system players work together to protect us from disease – and, most importantly, why they do it this way. Rigorously updated for this fifth edition, How the Immune System Works includes the latest information on subjects such as vaccines, the immunology of AIDS, and cancer. A highlight of this edition is a new chapter on the intestinal immune system – currently one of the hottest topics in immunology. Whether you are completely new to immunology, or require a refresher, How the Immune System Works will provide you with a clear and engaging overview of this fascinating subject. But don’t take our word for it! Read what students have been saying about this classic book: "What an exceptional book! It's clear you are in the hands of an expert." "Possibly the Best Small Text of All Time!" "This is a FUN book, and Lauren Sompayrac does a fantastic job of explaining the immune system using words that normal people can understand." "Hands down the best immunology book I have read... a very enjoyable read." "This is simply one of the best medical textbooks that I have ever read. Clear diagrams coupled with highly readable text make this whole subject easily understandable and engaging." Now with a brand new website at www.wiley.com/go/sompayrac featuring Powerpoint files of the images from the book

HIV/AIDS: A Very Short Introduction

HIV/AIDS: A Very Short Introduction PDF

Author: Alan Whiteside OBE

Publisher: OUP Oxford

Published: 2008-01-24

Total Pages: 174

ISBN-13: 0191578185

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HIV/AIDS is without doubt the worst epidemic to hit humankind since the Black Death. The first case was identified in 1981; by 2004 it was estimated that about 40 million people were living with the disease, and about 20 million had died. Despite rapid scientific advances there is still no cure and the drugs are expensive and toxic. Because of controversies and taboos surrounding safe drug usage and prostitution, the numbers of people infected continues to rise. However, it is in the developing world and especially parts of Africa that the real catastrophe is unfolding. In some of the worst affected countries life expectancy has plummeted to below 35 years, which has led to a serious decline in economic growth, a sharp rise in orphaning, and the imminent collapse of health care systems. The news is not all bleak though. There have been unprecedented breakthroughs in understanding diseases and developing drugs. Because the disease is so closely linked to sexual activity and drug use, the need to understand and change behaviour has caused us to reassess what it means to be human and how we should operate in the globalising world. This Very Short Introduction provides an introduction to the disease, tackling the science, the international and local politics, the fascinating demographics, and the devastating consequences of the disease, and explores how we have — and must — respond. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

The Limits of the Self

The Limits of the Self PDF

Author: Thomas Pradeu

Publisher: OUP USA

Published: 2012-02-27

Total Pages: 313

ISBN-13: 0199775281

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Immunology asserts that an individual can be defined through self and nonself. Thomas Pradeu argues that this theory is inadequate, because immune responses to self constituents and immune tolerance of foreign entities are the rule, not the exception.

Cancer: A Very Short Introduction

Cancer: A Very Short Introduction PDF

Author: Nick James

Publisher: OUP Oxford

Published: 2011-05-26

Total Pages: 152

ISBN-13: 0191620114

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In 1961 John F. Kennedy pledged to put a man on the moon by the end of the decade. Nine years later, Neil Armstrong and Buzz Aldrin walked on the moon. Ten years later, Richard Nixon echoed this pledge by declaring a 'war' on cancer. More than 30 years later, however, cancer remains one of the largest causes of death worldwide, with around 1 in 3 developing the disease. Curing cancer is not 'rocket science', but the question is, why has cancer proved to be harder to tackle than the moon landings turned out to be? Cancer research is a major economic activity. There are constant improvements in treatment techniques that result in better cure rates and increased quality and quantity of life for those with the disease, yet stories of breakthroughs in a cure for cancer are often in the media. In this Very Short Introduction Nick James, founder of the CancerHelp UK website, examines the trends in diagnosis and treatment of the disease, as well as its economic consequences. Asking what cancer is and what causes it, he considers issues surrounding expensive drug development, what can be done to reduce the risk of developing cancer, and the use of complementary and alternative therapies. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.