The Hippocampus in Clinical Neuroscience

The Hippocampus in Clinical Neuroscience PDF

Author: K. Szabo

Publisher: Karger Medical and Scientific Publishers

Published: 2014-04-23

Total Pages: 174

ISBN-13: 3318025682

DOWNLOAD EBOOK →

The hippocampus is one of the most intriguing structures of the human brain. Damage to this part causes symptoms ranging from transient disorders accompanied by tiny lesions to severely debilitating cognitive disorders with marked tissue loss. This publication provides a predominantly clinical approach to the complex workings of the hippocampus from different perspectives, ranging from basic principles to specific diseases. The first part of the book summarizes current knowledge regarding the structure and physiology of the hippocampus and establishes the ties to basic neuroscience. The second part deals with the function and assessment of the human hippocampus, including memory function, neuropsychological measures, and conventional and functional imaging studies. The chapters of the third part are devoted to the hippocampus in neurological disorders, e.g. the interaction between stress and memory function, and the pathological conditions of common as well as selected rare neurological diseases affecting the hippocampus. The book is highly recommended to clinical neurologists who wish to gain a broad understanding of this complex and fascinating organ in terms of basic principles, modern imaging findings, and specific diseases.

The Clinical Neurobiology of the Hippocampus

The Clinical Neurobiology of the Hippocampus PDF

Author: Thorsten Bartsch

Publisher: Oxford University Press

Published: 2012-07-26

Total Pages: 336

ISBN-13: 0191628956

DOWNLOAD EBOOK →

The hippocampus is one of the most studied structures in the human brain and plays a pivotal role in human memory function. Its recognized function is reflected by the presence of an extensive body of neurophysiological, neuropsychological, anatomical and neurocomputational literature that presents basic mechanisms, theoretical models and psychological concepts. However, in the rapidly growing field of hippocampal research, the clinical aspects of diseases that affect the hippocampus are greatly under-represented in current literature, and clinical approaches and concepts are scattered throughout various clinical and basic scientific disciplines. The Clinical Neurobiology of the Hippocampus explores clinical approaches to the range of diseases that affect the hippocampus. It brings together and reviews the common methods, clinical findings, concepts, mechanisms and, where applicable, therapeutic strategies for these clinical approaches. The clinical spectrum of hippocampal dysfunction encompasses a wide range of neurological, behavioural and psychiatric symptoms and surpasses the ability to encode, store and retrieve information. The relevance of hippocampal involvement in clinical diseases goes beyond mere neuropsychological deficits and includes psychopathological states in various conditions, such as acute amnesic syndromes, Alzheimer's disease, temporal lobe epilepsy (TLE), sleep, stroke medicine, limbic encephalitis, neurodevelopmental disorders, stress- and trauma-related disorders, depression, and schizophrenia. The first part of the book covers the basic and integrative features of the hippocampus, such as the anatomy and imaging of this structure, and the basic mechanisms of hippocampal function, including the principles of hippocampus-dependent memory processing in amnesia and sleep, the mechanisms of vulnerability and adult neurogenesis as well as the effects of stress. The second part covers the various clinical manifestations in which the hippocampus is involved and in which the preceding basic mechanisms are reflected. Bringing together a broad team of experts on the basic and clinical aspects of the hippocampus, the book provides an integrative view of the hippocampus. It is invaluable for neurologists, neuroscientists, and psychiatrists, and will stimulate interdisciplinary discussions in clinical neuroscience.

The Hippocampus Book

The Hippocampus Book PDF

Author: Per Andersen

Publisher: Oxford University Press

Published: 2007

Total Pages: 892

ISBN-13: 9780195100273

DOWNLOAD EBOOK →

The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it, and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behavior, and computational algorithms. Well-organized in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unraveling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf.

Gateway to Memory

Gateway to Memory PDF

Author: Mark A. Gluck

Publisher: MIT Press

Published: 2001

Total Pages: 470

ISBN-13: 9780262571524

DOWNLOAD EBOOK →

This book is for students and researchers who have a specific interest in learning and memory and want to understand how computational models can be integrated into experimental research on the hippocampus and learning. It emphasizes the function of brain structures as they give rise to behavior, rather than the molecular or neuronal details. It also emphasizes the process of modeling, rather than the mathematical details of the models themselves. The book is divided into two parts. The first part provides a tutorial introduction to topics in neuroscience, the psychology of learning and memory, and the theory of neural network models. The second part, the core of the book, reviews computational models of how the hippocampus cooperates with other brain structures -- including the entorhinal cortex, basal forebrain, cerebellum, and primary sensory and motor cortices -- to support learning and memory in both animals and humans. The book assumes no prior knowledge of computational modeling or mathematics. For those who wish to delve more deeply into the formal details of the models, there are optional "mathboxes" and appendices. The book also includes extensive references and suggestions for further readings.

Clinical Neuroscience

Clinical Neuroscience PDF

Author: Kelly Lambert

Publisher: Macmillan

Published: 2004-11-26

Total Pages: 666

ISBN-13: 9780716752271

DOWNLOAD EBOOK →

Integrating neurobiological mechanisms of general health into the coverage of mental disorders, this text also looks at other aspects of neuroscience and the ways in which it impacts on the mental condition.

Psychiatry and Clinical Neuroscience

Psychiatry and Clinical Neuroscience PDF

Author: Charles Zorumski

Publisher: Oxford University Press

Published: 2011-06-16

Total Pages: 322

ISBN-13: 0199768765

DOWNLOAD EBOOK →

Research in neuroscience is revolutionizing how we think about psychiatric diagnosis and treatment. Psychiatric disorders reflect dysfunction of the human mind and involve changes in cognition, emotion, and motivation. Understanding how the neural networks that underlie these mental functions become dysfunctional holds great promise for devising innovative approaches to diagnosis and treatment. Scientific progress is being driven, in part, by advances in human functional neuroimaging, which is being used to characterize the activity of specific brain circuits at rest and during the performance of specific tasks. Moreover, advances in clinical neuroscience are being coupled with expanding knowledge about genetics and cellular and synaptic neuroscience. Taken together, these advancements offer the hope of much more mechanism-based approaches to treatment in the future. Better understanding of neural circuits also can provide the basis for innovative psychotherapeutic strategies that take advantage of brain plasticity for purposes of neurorehabilitation. In this book, we examine recent developments in the field of network neuroscience and their potential impact on clinical psychiatry, including the way that psychiatrists are trained and interact with other medical specialties and mental health professionals.

Basic Clinical Neuroscience

Basic Clinical Neuroscience PDF

Author: Paul A. Young

Publisher: Lippincott Williams & Wilkins

Published: 2008

Total Pages: 422

ISBN-13: 9780781753197

DOWNLOAD EBOOK →

Basic Clinical Neuroscience offers medical and other health professions students a clinically oriented description of human neuroanatomy and neurophysiology. This text provides the anatomic and pathophysiologic basis for understanding neurologic abnormalities through concise descriptions of functional systems with an emphasis on medically important structures and clinically important pathways. It emphasizes the localization of specific anatomic structures and pathways with neurological deficits, using anatomy enhancing 3-D illustrations. Basic Clinical Neuroscience also includes boxed clinical information throughout the text, a key term glossary section, and review questions at the end of each chapter, making this book comprehensive enough to be an excellent Board Exam preparation resource in addition to a great professional training textbook. The fully searchable text will be available online at thePoint.

The Hippocampus from Cells to Systems

The Hippocampus from Cells to Systems PDF

Author: Deborah E. Hannula

Publisher: Springer

Published: 2017-03-01

Total Pages: 589

ISBN-13: 3319504061

DOWNLOAD EBOOK →

The hippocampus has long been considered a critical substrate in the neurobiology, neuropsychology, and cognitive neuroscience of memory. Over the past few decades, a number of ground-breaking theoretical and methodological advances have radically enhanced our understanding of the structure and function of the hippocampus and revolutionized the neuroscientific study of memory. Cutting across disciplines and approaches, these advances offer novel insights into the molecular and cellular structure and physiology of the hippocampus, the role of hippocampus in the formation, (re)consolidation, enhancement, and retrieval of memory across time and development, and permit investigators to address questions about how the hippocampus interacts, functionally and anatomically, with other neural systems in service of memory. In addition, recent investigations also suggest that the mechanistic properties and functional processing features of the hippocampus permit broader contributions to cognition, beyond memory, to the domains of attention, decision-making, language, social cognition, and a variety of other capacities that are critical for flexible cognition and behavior. These advances have profound implications for the neurobiology and cognitive neuroscience of hippocampus dependent cognition and for the numerous psychiatric and neurological diseases and disorders for which hippocampal pathology is a hallmark such as Alzheimer’s disease and schizophrenia. The goal of this book is to bring together in a single source an integrated review of these advances providing state of the art treatment on the structure and function of the hippocampus. Contributors will examine the hippocampus from a variety of levels (from cells to systems) using a wide range of methods (from neurobiological approaches in non-human animals to neuroimaging and neuropsychological work in humans).

Neuropsychiatry, Neuropsychology, and Clinical Neuroscience

Neuropsychiatry, Neuropsychology, and Clinical Neuroscience PDF

Author: Rhawn Joseph

Publisher: Lippincott Williams & Wilkins

Published: 1996

Total Pages: 864

ISBN-13: 9780683044850

DOWNLOAD EBOOK →

This volume on the relationship between neuroanatomy and associated behaviour, thinking and emotions, provides a synthesis of findings from all fields in the neuroscience, medical, developmental, evolutionary and clinical literature regarding brain-behaviour relationships. It shows how the brain works in consciousness, memory, language, and emotion, and deals with psychiatric abnormalities resulting from specific brain injuries.

Fundamental Neuroscience for Basic and Clinical Applications,with STUDENT CONSULT Online Access,4

Fundamental Neuroscience for Basic and Clinical Applications,with STUDENT CONSULT Online Access,4 PDF

Author: Duane E. Haines

Publisher: Elsevier Health Sciences

Published: 2013-01-01

Total Pages: 536

ISBN-13: 1437702945

DOWNLOAD EBOOK →

Turn to Fundamental Neuroscience for a thorough, clinically relevant understanding of this complicated subject! Integrated coverage of neuroanatomy, physiology, and pharmacology, with a particular emphasis on systems neurobiology, effectively prepares you for your courses, exams, and beyond. Easily comprehend and retain complex material thanks to the expert instruction of Professor Duane Haines, recipient of the Henry Gray/Elsevier Distinguished Teacher Award from the American Association of Anatomists and the Distinguished Teacher Award from the Association of American Colleges.Access the complete contents online at www.studentconsult.com, plus 150 USMLE-style review questions, sectional images correlated with the anatomical diagrams within the text, and more. Grasp important anatomical concepts and their clinical applications thanks to correlated state-of-the-art imaging examples, anatomical diagrams, and histology photos.Retain key information and efficiently study for your exams with clinical highlights integrated and emphasized within the text.