The Foundations of Genetics

The Foundations of Genetics PDF

Author: F. A. E. Crew

Publisher: Elsevier

Published: 2014-06-28

Total Pages: 229

ISBN-13: 1483282651

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The Foundations of Genetics describes the historical development of genetics with emphasis on the contributions to advancing genetical knowledge and the various applications of genetics. The book reviews the work of Gregor Mendel, his Law of Segregation, and of Ernst Haeckel who suggested that the nucleus is that part of the cell that is responsible for heredity. The text also describes the studies of W. Johannsen on "pure lines," and his introduction of the terms gene, genotype, and phenotype. The book explains the theory of the gene and the notion that hereditary particles are borne by the chromosomes (Sutton-Boveri hypothesis). Of the constituent parts of the nucleus only the chromatin material divides at mitosis and segregates during maturation. Following studies confirm that the chromatin material, present in the form of chromosomes with a constant and characteristic number and appearance for each species, is indeed the hereditary material. The book describes how Muller in 1927, showed that high precision energy radiation is the external cause to mutation in the gene itself if one allele can mutate without affecting its partner. The superstructure of genetics built upon the foundations of Mendelism has many applications including cytogenetics, polyploidy, human genetics, eugenics, plant breeding, radiation genetics, and the evolution theory. The book can be useful to academicians and investigators in the fields of genetics such as biochemical, biometrical, microbial, and pharmacogenetics. Students in agriculture, anthropology, botany, medicine, sociology, veterinary medicine, and zoology should add this text to their list of primary reading materials.

Foundations of Mathematical Genetics

Foundations of Mathematical Genetics PDF

Author: Anthony William Fairbank Edwards

Publisher: Cambridge University Press

Published: 2000-01-13

Total Pages: 138

ISBN-13: 9780521775441

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A definitive account of the origins of modern mathematical population genetics, first published in 2000.

Science as a Way of Knowing

Science as a Way of Knowing PDF

Author: John Alexander Moore

Publisher: Harvard University Press

Published: 1993

Total Pages: 548

ISBN-13: 9780674794825

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This book makes Moore's wisdom available to students in a lively, richly illustrated account of the history and workings of life. Employing rhetoric strategies including case histories, hypotheses and deductions, and chronological narrative, it provides both a cultural history of biology and an introduction to the procedures and values of science.

A History of Genetics

A History of Genetics PDF

Author: Alfred Henry Sturtevant

Publisher: CSHL Press

Published: 2001

Total Pages: 190

ISBN-13: 9780879696078

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In the small “Fly Room†at Columbia University, T.H. Morgan and his students, A.H. Sturtevant, C.B. Bridges, and H.J. Muller, carried out the work that laid the foundations of modern, chromosomal genetics. The excitement of those times, when the whole field of genetics was being created, is captured in this book, written in 1965 by one of those present at the beginning. His account is one of the few authoritative, analytic works on the early history of genetics. This attractive reprint is accompanied by a website, http://www.esp.org/books/sturt/history/ offering full-text versions of the key papers discussed in the book, including the world's first genetic map.

The Foundations of Population Genetics

The Foundations of Population Genetics PDF

Author: Daniel M. Weinreich

Publisher: MIT Press

Published: 2023-08-29

Total Pages: 255

ISBN-13: 0262372576

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An accessible but rigorous treatment of the theoretical foundations of population genetics. Population genetics—the branch of evolutionary biology concerned with understanding how and why populations’ genetic compositions change over time—rests on a well-developed theoretical foundation that draws on genetics, mathematics, and computer science. This textbook provides an approachable but rigorous treatment for advanced undergraduate and graduate students interested in building a quantitative understanding of the genetics of evolution. Existing texts either assume very mathematically advanced readers, or avoid much of the underlying theory, instead focusing on current methods of data analysis. In contrast, The Foundations of Population Genetics develops the theory from first principles. Requiring only confidence in algebra, this self-contained, student-friendly book illustrates the conceptual framework, terminology, and methods of mathematical modeling. It progressively introduces concepts from genetics as needed, while emphasizing biological implications throughout. As a result, readers come away with a deep understanding of the structure of population genetics without needing to master its mathematics. Connects theory with the most recent genetic data better than existing texts Features engaging real-world examples and extensive original figures Provides dozens of carefully scaffolded questions that deepen the reader's understanding of key concepts Ideal as a succinct reference for established scientists in biology, medicine, and computer science Instructor resources available

Evolution and the Genetics of Populations, Volume 2

Evolution and the Genetics of Populations, Volume 2 PDF

Author: Sewall Wright

Publisher: University of Chicago Press

Published: 1969

Total Pages: 520

ISBN-13: 9780226910505

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"Wright's views about population genetics and evolution are so fundamental and so comprehensive that every serious student must examine these books firsthand. . . . Publication of this treatise is a major event in evolutionary biology."-Daniel L. Hartl, BioScience