The Chromosomal Code
Author: Lawrence Watt-Evans
Publisher: Avon Books
Published: 1984
Total Pages: 204
ISBN-13: 9780380872053
DOWNLOAD EBOOK →Author: Lawrence Watt-Evans
Publisher: Avon Books
Published: 1984
Total Pages: 204
ISBN-13: 9780380872053
DOWNLOAD EBOOK →Author: Lawrence Watt-Evans
Publisher: Misenchanted Press
Published: 2020-12-27
Total Pages: 179
ISBN-13: 161991039X
DOWNLOAD EBOOK →A sudden inexplicable ice age has driven Earth's population into the tropics, except for a few die-hards eking out a tenuous existence scavenging the snow-covered ruins of civilization. One such straggler is John Starkman, making his home in the frozen wastes of western Pennsylvania. Already an outcast because of a certain physical peculiarity, he saw no reason to join his neighbors in fleeing south.
Author: Bruce Alberts
Publisher:
Published: 2002
Total Pages: 0
ISBN-13: 9780815332183
DOWNLOAD EBOOK →Author: National Research Council
Publisher: National Academies Press
Published: 1988-01-01
Total Pages: 128
ISBN-13: 0309038405
DOWNLOAD EBOOK →There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
Author: M. Clark
Publisher: Springer
Published: 1996-06-30
Total Pages: 364
ISBN-13:
DOWNLOAD EBOOK →This text presents a concise account of modern cytogenetics. Basic facts are presented together with illustrative examples from plant, animal and medical cytogenetics. Selected references guide the reader to recent literature. New molecular cytogenetics techniques are reviewed.
Author: Adrian T. Sumner
Publisher: John Wiley & Sons
Published: 2008-04-30
Total Pages: 304
ISBN-13: 0470695226
DOWNLOAD EBOOK →Integrating classical knowledge of chromosome organisation with recent molecular and functional findings, this book presents an up-to-date view of chromosome organisation and function for advanced undergraduate students studying genetics. The organisation and behaviour of chromosomes is central to genetics and the equal segregation of genes and chromosomes into daughter cells at cell division is vital. This text aims to provide a clear and straightforward explanation of these complex processes. Following a brief historical introduction, the text covers the topics of cell cycle dynamics and DNA replication; mitosis and meiosis; the organisation of DNA into chromatin; the arrangement of chromosomes in interphase; euchromatin and heterochromatin; nucleolus organisers; centromeres and telomeres; lampbrush and polytene chromosomes; chromosomes and evolution; chromosomes and disease, and artificial chromosomes. Topics are illustrated with examples from a wide variety of organisms, including fungi, plants, invertebrates and vertebrates. This book will be valuable resource for plant, animal and human geneticists and cell biologists. Originally a zoologist, Adrian Sumner has spent over 25 years studying human and other mammalian chromosomes with the Medical Research Council (UK). One of the pioneers of chromosome banding, he has used electron microscopy and immunofluorescence to study chromosome organisation and function, and latterly has studied factors involved in chromosome separation at mitosis. Adrian is an Associate Editor of the journal Chromosome Research, acts as a consultant biologist and is also Chair of the Committee of the International Chromosome Conferences. The most up-to-date overview of chromosomes in all their forms. Introduces cutting-edge topics such as artificial chromosomes and studies of telomere biology. Describes the methods used to study chromosomes. The perfect complement to Turner.
Author: Matt Ridley
Publisher: Harper Collins
Published: 2013-03-26
Total Pages: 370
ISBN-13: 0062253468
DOWNLOAD EBOOK →“Ridley leaps from chromosome to chromosome in a handy summation of our ever increasing understanding of the roles that genes play in disease, behavior, sexual differences, and even intelligence. . . . . He addresses not only the ethical quandaries faced by contemporary scientists but the reductionist danger in equating inheritability with inevitability.” — The New Yorker The genome's been mapped. But what does it mean? Matt Ridley’s Genome is the book that explains it all: what it is, how it works, and what it portends for the future Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life. Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.
Author: Julianne Zedalis
Publisher:
Published: 2017-10-16
Total Pages: 1923
ISBN-13: 9781947172401
DOWNLOAD EBOOK →Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.
Author: M. Clark
Publisher: Springer
Published: 1996-07-14
Total Pages: 0
ISBN-13: 9789400900738
DOWNLOAD EBOOK →to the expression of oncogenes, which are pivotal in cancer genetics. Accurate delineation and prognosis of a cancer may depend upon careful cytogenetic analysis. Cytogenetics is still of great importance when monitoring changes in somatic cell hybrids. The role of chromosome genetics within modern biology is continually changing and evolving, and thus a knowledge of cytogenetics is of ever-increasing value. Chromatin structure 1 and replication Summary It is now a well-known fact that DNA is the hereditary material and that the vast majority of the DNA of an organism is housed in organelles called chromo somes. However, the length of DNA contained in a cell is far greater than the size of the cell within which it exists; for example, the shortest human chromosome consists of 1. 4 cm of DNA which must be compacted into a cell only a few micrometres across. To achieve this, DNA has to undergo several levels of packing, a process that is a mixture of DNA-DNA and DNA protein interactions. The most compact form of DNA can be seen under the light microscope as a meta phase chromosome during mitotic cell division. DNA must also be faithfully replicated to ensure accurate cell function and maintenance of the organ ism as well as ultimately, the reproduction of the species. Our current knowledge of these complex processes is very limited, with huge gaps, in particular, concern ing the links between the molecular and organelle level of organization.
Author: Herman E. Wyandt
Publisher: Springer
Published: 2017-03-28
Total Pages: 500
ISBN-13: 9811030359
DOWNLOAD EBOOK →This new edition now titled “Human Chromosome Variation: Heteromorphism, Polymorphism and Pathogenesis” provides the reader with an up-to-date overview of microarrays, fragile sites, copy number variations and whole genome sequencing. Greatly expanding the discussion of microarray analysis in the previous edition of the book, are new chapters on microarray and genomic analysis, plus comprehensive tables on the subtle microdeletions and microduplications that are found on each chromosome, including 235 recurring copy number variants that are associated with well-established or emerging chromosomal syndromes. The current edition features concise information on cytogenetic methods and applications, extending these discussions to DNA analysis and genome sequencing. Sections on euchromatin, heterochromatin, FISH pattern, fragile site, copy number, and DNA sequence variation are integrated with actual clinical examples from cytogenetic laboratories and from clinical practice. The principles that allow for the distinction between benign chromosome / DNA variation and pathogenic heteromorphisms / polymorphisms are discussed and include references to the latest organizational guidelines and genomic or population databases. The two previous incarnations of this book: the ‘Atlas of Human Chromosome Heteromorphism’, and ‘Human Chromosome Variation: Heteromorphism and Polymorphism’ have been standard reference works in most cytogenetic laboratories, used by laboratory directors and clinicians all around the world. While widely used sections from the previous edition on cytogenetic technologies and heteromorphisms are retained intact the present volume adds extensive material on copy number variations (polymorphisms detected by microarray analysis), fragile sites in disease and cancer, and practical views on interpreting emerging technologies, including whole exome sequencing. This book should be of interest to clinicians, technicians and students who are or will be exposed to DNA and/or chromosome analysis and the data derived from these continuously developing techniques. This fully updated book volume will bring the reader up to speed on the latest technologies, their applications, benefits and drawbacks and as such, is a must read for anyone with an interest in DNA and chromosome analysis and the distinction between benign variation and pathogenic mistakes.