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The Breakthrough

Author: Charles Graeber

Publisher: Twelve

Published: 2018-11-13

Total Pages: 298

ISBN-13: 145556849X

Follow along as this New York Times bestselling author details the astonishing scientific discovery of the code to unleashing the human immune system to fight in this "captivating and heartbreaking" book (The Wall Street Journal). For decades, scientists have puzzled over one of medicine's most confounding mysteries: Why doesn't our immune system recognize and fight cancer the way it does other diseases, like the common cold? As it turns out, the answer to that question can be traced to a series of tricks that cancer has developed to turn off normal immune responses -- tricks that scientists have only recently discovered and learned to defeat. The result is what many are calling cancer's "penicillin moment," a revolutionary discovery in our understanding of cancer and how to beat it. In The Breakthrough, New York Times bestselling author of The Good Nurse Charles Graeber guides readers through the revolutionary scientific research bringing immunotherapy out of the realm of the miraculous and into the forefront of twenty-first-century medical science. As advances in the fields of cancer research and the human immune system continue to fuel a therapeutic arms race among biotech and pharmaceutical research centers around the world, the next step -- harnessing the wealth of new information to create modern and more effective patient therapies -- is unfolding at an unprecedented pace, rapidly redefining our relationship with this all-too-human disease. Groundbreaking, riveting, and expertly told, The Breakthrough is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history.

The Immunotherapy Revolution

Author: Jason R. Williams

Publisher:

Published: 2019-10-15

Total Pages: 216

ISBN-13: 9781700114938

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The Future Of Treating Cancer Has Finally Arrived.Cancer treatments can be torture! Surgery, chemotherapy, and radiation are not only extreme but can be just as painful and dangerous as the cancer itself. When doctors treat cancer aggressively it leaves the body in a weakened, susceptible state open to contracting other diseases or relapses. Most of the medical field refuses to acknowledge the major problems with the way they treat cancer. So is there really a better way to heal from cancer against all odds? YES!In this eye-opening book, Dr. Williams shares his most groundbreaking, shocking conclusions from his decades of in-depth research on cancer. He provides life-changing advice in the most critical and overlooked areas in cancer treatment and recovery. He has personally developed a revolutionary medical treatment that will change the way we treat cancer - forever.Dr. Jason R. Williams is a board-certified radiologist, image-guided oncologist, researcher, and professor. He is the Founder and Director of Interventional Oncology for the Williams CancerInstitute and adjunct professor at Case Western Reserve University. He has pioneered a brand new less invasive, less toxic solution to treating cancer.Committed to further advance research in intra-tumoral immunotherapy and help those who are struggling financially to cover medical costs, Dr. Williams is donating all proceeds from this book for this cause. Grab your copy now, and discover the promising solution to cancer!

The Beautiful Cure

Author: Daniel M. Davis

Publisher: University of Chicago Press

Published: 2021-03-19

Total Pages: 271

ISBN-13: 022637114X

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“Visceral.”—Wall Street Journal “Illuminating.”—Publishers Weekly “Heroic.”—Science The immune system holds the key to human health. In The Beautiful Cure, leading immunologist Daniel M. Davis describes how the scientific quest to understand how the immune system works—and how it is affected by stress, sleep, age, and our state of mind—is now unlocking a revolutionary new approach to medicine and well-being. The body’s ability to fight disease and heal itself is one of the great mysteries and marvels of nature. But in recent years, painstaking research has resulted in major advances in our grasp of this breathtakingly beautiful inner world: a vast and intricate network of specialist cells, regulatory proteins, and dedicated genes that are continually protecting our bodies. Far more powerful than any medicine ever invented, the immune system plays a crucial role in our daily lives. We have found ways to harness these natural defenses to create breakthrough drugs and so-called immunotherapies that help us fight cancer, diabetes, arthritis, and many age-related diseases, and we are starting to understand whether activities such as mindfulness might play a role in enhancing our physical resilience. Written by a researcher at the forefront of this adventure, The Beautiful Cure tells a dramatic story of scientific detective work and discovery, of puzzles solved and mysteries that linger, of lives sacrificed and saved. With expertise and eloquence, Davis introduces us to this revelatory new understanding of the human body and what it takes to be healthy.

At Face Value

Author: Terry Healey

Publisher: Caveat Press

Published: 2006

Total Pages: 234

ISBN-13: 9781883991982

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Terry Healey was a junior at the University of California at Berkeley. At the age of twenty, his life had been smooth sailing, seldom interrupted with adversity or difficulty. Terry was confident and not concerned much with his appearance. But out of nowhere, a lump formed behind his right nostril. Cancer. He fought it and survived. But after multiple surgeries and radiation treatment, Terry would discover that he hadn't even begun to deal with what would become his greatest struggle for years to come -- the disfigurement that resulted from it.

The Good Nurse

Author: Charles Graeber

Publisher: Twelve

Published: 2013-04-15

Total Pages: 353

ISBN-13: 1455506125

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The mesmerizing basis of the movie starring Eddie Redmayne and Jessica Chastain⁠—a “stunning book...that should and does bring to mind In Cold Blood”—takes you inside the mind of America's most prolific serial killer, whose 16-year long "nursing" career left as many as 400 dead. (New York Times) Edgar Award Nomination, Mystery Writers of America BBC (Top Ten Books of the Year) “The best books I read this year” (top ten books, EW) —Stephen King “The Best Journalism of the Year.". —The Daily Beast “The most terrifying book published this year. It is also one of the most thoughtful...call it literary true crime...” —Kirkus Reviews ("Best Books of the year") After his December 2003 arrest, registered nurse Charlie Cullen was quickly dubbed "The Angel of Death" by the media. But Cullen was no mercy killer, nor was he a simple monster. He was a favorite son, a husband and beloved father, a best friend and a celebrated caregiver. Implicated in the deaths of as perhaps as many as 400 patients, he was also perhaps the most prolific serial killer in American history. When, in March of 2006, Charles Cullen was marched from his final sentencing in an Allentown, Pennsylvania, courthouse into a waiting police van, it seemed certain that the chilling secrets of his life, career, and capture would disappear with him. Now, in a riveting piece of investigative journalism nearly ten years in the making, Charles Graeber gives us the unbelievable true story. Based on hundreds of pages of previously unseen police records, wire-tap recordings and videotapes and interviews with whistleblowers and confidential informants, and years of exclusive jailhouse conversations with Cullen himself, the homicide detectives who worked against the clock and administrators to try and finally crack the code on Cullen’s crimes, and Cullen’s fellow nurse Amy, an overworked single mom asked to choose between protecting her friend Charlie and stopping a potential serial killer, THE GOOD NURSE weaves an urgent and terrifying tale of madness, humanity and heroism. Cullen's murderous career in the world's most trusted profession spanned sixteen years and nine hospitals. Time and again he was fired or allowed to resign. But Cullen continued to work and kill, shielded by a hospital system that, by accident or design, successfully protected the institution while failing to protect patients. THE GOOD NURSE is a searing indictment of a crushing and dehumanizing for-profit medical system, and an inspiring human story of the previously unknown individuals who chose to risk their jobs and lives to do the right thing. Mesmerizing and irresistibly paced, this book will make you look at hospitals and the people who work in them in an entirely different way.

The Basics of Cancer Immunotherapy

Author: Haidong Dong

Publisher: Springer

Published: 2018-01-05

Total Pages: 160

ISBN-13: 3319706225

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This book provides patients and their physicians (especially “non-oncologist” health care providers) with a clear and concise introduction to cancer immunotherapy, which, unlike traditional forms of cancer therapy, acts by boosting the patient’s own immune system to fight cancer. The unique features of cancer immunotherapy make its management, monitoring and side-effects different from those of traditional cancer therapy. Especially novel are the side effects of cancer immunotherapy, necessitating greater awareness for both patients and physicians in order to minimize complications of therapy. The patient-friendly, concise, easy-to-understand, and up-to-date knowledge presented in this book will inform patients about the benefits and risks of cancer immunotherapy, and help them and their care providers to understand how immunotherapy would control their unique disease. Researchers and academic professionals in the field of cancer immunotherapy will also find clear and useful information to help them communicate with patients or address unresolved problems. Some key features of the book are: Expertise. All editors and authors are scientists and oncologists specializing in cancer immunotherapy, and are involved in scientific discovery from the early stage of immune-checkpoint inhibitors to today’s daily patient care. Their insights, expertise and experience guarantee the high quality and authority in the science, medicine and practice of cancer immunotherapy. Patient-friendly. This book is written for cancer patients in order to meet their needs when considering immunotherapy. As an educational tool, this book will help the reader balance the risks and benefits based on both science and clinical facts, and therefore to make the best choice in receiving or withdrawing from immunotherapy. Disease Specificity. Cancer is a complicated disease involving multiple stages and pathology. Its response to immunotherapy is individualized and varies depending on cancer types. The authors’ expertise in treating different types of cancers, including melanoma, lung, kidney, bladder, and lymphoma, provides disease-specific insights in applying immunotherapy to each disease.

The Death of Cancer

Author: Vincent T. DeVita, Jr., M.D.

Publisher: Sarah Crichton Books

Published: 2015-11-03

Total Pages: 336

ISBN-13: 0374714177

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Cancer touches everybody’s life in one way or another. But most of us know very little about how the disease works, why we treat it the way we do, and the personalities whose dedication got us where we are today. For fifty years, Dr. Vincent T. DeVita Jr. has been one of those key players: he has held just about every major position in the field, and he developed the first successful chemotherapy treatment for Hodgkin’s lymphoma, a breakthrough the American Society of Clinical Oncologists has called the top research advance in half a century of chemotherapy. As one of oncology’s leading figures, DeVita knows what cancer looks like from the lab bench and the bedside. The Death of Cancer is his illuminating and deeply personal look at the science and the history of one of the world’s most formidable diseases. In DeVita’s hands, even the most complex medical concepts are comprehensible. Cowritten with DeVita’s daughter, the science writer Elizabeth DeVita-Raeburn, The Death of Cancer is also a personal tale about the false starts and major breakthroughs, the strong-willed oncologists who clashed with conservative administrators (and one another), and the courageous patients whose willingness to test cutting-edge research helped those oncologists find potential treatments. An emotionally compelling and informative read, The Death of Cancer is also a call to arms. DeVita believes that we’re well on our way to curing cancer but that there are things we need to change in order to get there. Mortality rates are declining, but America’s cancer patients are still being shortchanged—by timid doctors, by misguided national agendas, by compromised bureaucracies, and by a lack of access to information about the strengths and weaknesses of the nation’s cancer centers. With historical depth and authenticity, DeVita reveals the true story of the fight against cancer. The Death of Cancer is an ambitious, vital book about a life-and-death subject that touches us all.

A Cure Within

Author: Neil Canavan

Publisher:

Published: 2018

Total Pages: 277

ISBN-13: 9781621822172

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Cancer. There are few words in the English language having such a visceral, personal impact. Cancer patient. Cancer survivor. Pretty much anyone over the age of 30 knows one. A family member. A friend. Someone lost too soon. Someone forever changed. But we don't really like to talk about it, because there's really not much we can do. We fight cancer, sure, but we rarely win. Defeating cancer is one of medical science's greatest challenges. So when a novel approach to treatment seems promising, there is an intense interest in its progress and those who are making it. This book is about both - the progress and the pioneers - and its focus is the revolutionary science of something called cancer immunotherapy. This medical marvel, cancer immunotherapy - also called immuno-oncology - is still in its infancy. Yet, mobilizing the immune system to recognize and attack cancer has long been imagined, and occasionally attempted, for more than 100 years: It is only just recently that significant - in fact, unprecedented - progress has been made. With the use of newly approved immunotherapy treatments, there are now reports of hundreds, if not thousands of cancer patients with advanced disease living years beyond all prior expectation. Some of these once-terminally ill patients are now called "cured." This has never happened before. As Dr. Jill O'Donnell-Tormey comments in the Foreword, "It has taken decades of basic research and billions of dollars of investment to build the foundation upon which today's lifesaving treatments are based. This book offers a uniquely entertaining yet inspiring glimpse into the lives and minds of the academic and industry pioneers who forged this new field. It is a story of how an obscure and oft-derided field of cancer research - and the tenacious few scientists who refused to abandon it - came from behind to become the new 'darling of oncology.'" The book's author, Neil Canavan, is an experienced commentator on new developments in medical science. His portraits of 25 of the pioneers in immunotherapy are the culmination of two years of travel to laboratories, offices, and conferences around the world and countless hours of conversation with individuals immersed in a vitally important, promising assault on a dread disease that kills more than eight million people each year worldwide. -- from dust jacket.

Invisible Frontiers

Author: Stephen S. Hall

Publisher: Oxford University Press, USA

Published: 2002

Total Pages: 0

ISBN-13: 9780195151596

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Author Stephen Hall weaves together the scientific, social and political threads of this story - the fierce rivalry between labs, the fateful clash of egos within labs, the invasion of academia by commerce, the public fears about genetic engineering, the threat of government regulation, and the ultimate triumph of modern biology - to give us an outstanding tale of scientific research."--BOOK JACKET.

Immunotherapy of Hepatocellular Carcinoma

Author: Tim F. Greten

Publisher: Springer

Published: 2017-10-04

Total Pages: 167

ISBN-13: 3319649582

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In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer. Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.