Antipsychotic Drugs and Their Side-Effects

Antipsychotic Drugs and Their Side-Effects PDF

Author: Thomas R.E. Barnes

Publisher: Academic Press

Published: 2013-10-22

Total Pages: 304

ISBN-13: 1483288102

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In line with other volumes in the Neuroscience Perspectives Series, this volume covers the background, pharmacology, molecular biology, and biochemistry of antipsychotic drugs, together with an overview assessment of the therapeutic considerations. Over the past 40 years, the effectiveness of conventional neuroleptic agents for psychotic illness has been offset by a wide range of adverse side-effects, including motor side-effects like parkinsonism. Studies show that lowering doses may still produce the antipsychotic effect while lessening the risk of side-effects. As all available antispychotic drugs are able to block dopamine, specifically D2 receptors, doses below the threshold level for producing acute motor disorder can still be therapeutically effective. With the identification and characterization of multiple dopamine receptors, the possibility of more selective drugs with better side-effect potential has arisen. Other novel antipsychotic agents include D1 receptor blockers, partial dopamine agonists and non-dopamine drugs such as 5-HT receptor blockers, sigma receptor antagonists and NMDA receptor agonists. This volume reviews both the basic science of the conventional and atypical neuroleptics and their present and potential therapeutic use.

NeuroPsychopharmacotherapy

NeuroPsychopharmacotherapy PDF

Author: Peter Riederer

Publisher: Springer Nature

Published: 2022-11-04

Total Pages: 4652

ISBN-13: 303062059X

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This book provides a reference guide describing the current status of medication in all major psychiatric and neurological indications, together with comparisons of pharmacological treatment strategies in clinical settings in Europe, USA, Japan and China. In addition, it highlights herbal medicine as used in China and Japan, as well as complementary medicine and nutritional aspects. This novel approach offers international readers a global approach in a single dedicated publication and is also a valuable resource for anyone interested in comparing treatments for psychiatric disorders in three different cultural areas. There are three volumes devoted to Basic Principles and General Aspects, offering a general overview of psychopharmacotherapy (Vol. 1); Classes, Drugs and Special Aspects covering the role of psychotropic drugs in the field of psychiatry and neurology (Vol. 2) and Applied Psychopharmacotherapy focusing on applied psychopharmacotherapy (Vol. 3). These books are invaluable to psychiatrists, neurologists, neuroscientists, medical practitioners and clinical psychologists.

Neurotransmitter Receptors in Actions of Antipsychotic Medications

Neurotransmitter Receptors in Actions of Antipsychotic Medications PDF

Author: Michael S. Lidow

Publisher: CRC Press

Published: 2000-06-22

Total Pages: 274

ISBN-13: 1420041770

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Years of extensive investigation into neurophysiology, neurochemistry, and behavioral pharmacology have produced an understanding of antipsychotic medication action that is much more refined than the original dopamine hypothesis. New perspectives offer an array of novel drugs - drugs that pose a lower risk of developing tardive dyskinesia, have few

First Episode Psychosis

First Episode Psychosis PDF

Author: Katherine J. Aitchison

Publisher: CRC Press

Published: 2022-03-26

Total Pages: 152

ISBN-13: 0429524145

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The new edition of this popular handbook has been thoroughly updated to include the latest data concerning treatment of first-episode patients. Drawing from their experience, the authors discuss the presentation and assessment of the first psychotic episode and review the appropriate use of antipsychotic agents and psychosocial approaches in effective management. This is an authoritative text written by a team of highly respected authors for psychiatrists, neurologists, primary care practitioners and health care professional working in psychiatry. Drawing from their experience, the presentation and assessment of the first psychotic episode are discussed, details regarding antipsychotic drugs and their appropriate use are reviewed and psychosocial approaches are examined. The resulting book offers a concise and valuable guide to those wishing to review the latest proposals for the treatment of first-episode psychosis supported by up-to-date references, in a single publication.

Pharmacological Treatment of Mental Disorders in Primary Health Care

Pharmacological Treatment of Mental Disorders in Primary Health Care PDF

Author: World Health Organization

Publisher: World Health Organization

Published: 2009

Total Pages: 80

ISBN-13: 9241547693

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This manual attempts to provide simple, adequate and evidence-based information to health care professionals in primary health care especially in low- and middle-income countries to be able to provide pharmacological treatment to persons with mental disorders. The manual contains basic principles of prescribing followed by chapters on medicines used in psychotic disorders; depressive disorders; bipolar disorders; generalized anxiety and sleep disorders; obsessive compulsive disorders and panic attacks; and alcohol and opioid dependence. The annexes provide information on evidence retrieval, assessment and synthesis and the peer view process.

Novel Antipsychotic Drugs

Novel Antipsychotic Drugs PDF

Author: Herbert Y. Meltzer

Publisher: Raven Press (ID)

Published: 1992

Total Pages: 296

ISBN-13:

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Contains highlights of an American College of Neuropsychopharmacology conference on new directions in the development of atypical and other novel antipsychotic drugs. Presents new theories and preclinical and clinical data on various drugs and classes of drugs including amperozide and other drugs.

The Bitterest Pills

The Bitterest Pills PDF

Author: J. Moncrieff

Publisher: Springer

Published: 2013-09-15

Total Pages: 248

ISBN-13: 1137277440

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A challenging reappraisal of the history of antipsychotics, revealing how they were transformed from neurological poisons into magical cures, their benefits exaggerated and their toxic effects minimized or ignored.

Marsden's Book of Movement Disorders

Marsden's Book of Movement Disorders PDF

Author: Ivan Donaldson

Publisher: Oxford University Press

Published: 2012-03-29

Total Pages: 1512

ISBN-13: 0191502243

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This book represents the final work of the late Professor C. David Marsden, who was the most influential figure in the field of movement disorders, in terms of his contributions to both research and clinical practice, in the modern era. It was conceived and written by David Marsden and his colleague at the Institute of Neurology, Prof. Ivan Donaldson. It was their intention that this would be the most comprehensive book on movement disorders and also that it would serve as the 'clinical Bible' for the management of these conditions. It provides a masterly survey of the entire topic, which has been made possible only by vast laboratory and bedside experience. Marsden's Book of Movement Disorders covers the full breadth of movement disorders, from the underlying anatomy and understanding of basal ganglia function to the diagnosis and management of specific movement disorders, including the more common conditions such as Parkinson's Disease through to rare, and very rare conditions such as Niemann-Pick disease. Chapters follow a structured format with historical overviews, definitions, clinical features, differential diagnosis, investigations and treatment covered in a structured way. It is extensively illustrated with many original photographs and diagrams of historical significance. Among these illustrations are still images of some original film clips of some of Dr. Marsden's patients published here for the first time. Comprehensively referenced and updated by experts from the Institute of Neurology at Queen Square, this book is a valuable reference for, not just movement disorder specialists and researchers, but also for clinicians who care for patients with movement disorders.