eBook PDF Download Digital Library
Author: Hugh Jones
Publisher: Oxford University Press, USA
Published: 2008-09-25
Total Pages: 179
ISBN-13: 0199545138
DOWNLOAD EBOOK →This book provides a background of essential knowledge on testosterone deficiency in men, including diagnosis and treatment. It also explores the associations of testosterone deficiency with organ systems and their diseases e.g diabetes, osteoporosis.
Author: Susan Nieschlag
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 296
ISBN-13: 3662008149
DOWNLOAD EBOOK →New developments in testosterone therapy are summarized here by internationally renowned experts. They review both basic and clinical knowledge in fourteen chapters. The book begins with the biochemistry of testosterone, its biosynthesis, metabolism and mechanisms of action in target organs. Three chapters deal with specific aspects of testosterone action, namely its role in spermatogenesis, its psychotropic effects and its effects on bones. Syndromes caused by androgen resistance are described in order to highlight the importance of properly functioning enzymes and receptors in the target organs. Causes and symptoms of male hypogonadism, the major indication for testosterone treatment, are described. Five chapters are devoted to the pharmacology, pharmacokinetics and clinical uses and abuses of testosterone preparations. The new transdermal testosterone application is described in detail. Side effects of testosterone treatment are reviewed. The possible role of androgens in the development of prostatic hypertrophy and carcinoma is discussed extensively since this question is of major concern to the clinician.
Author: Institute of Medicine
Publisher: National Academies Press
Published: 2004-03-12
Total Pages: 239
ISBN-13: 0309090636
DOWNLOAD EBOOK →Popular culture often equates testosterone with virility, strength, and the macho male physique. Viewed by some as an "antiaging tonic," testosterone's reputation and increased use by men of all ages in the United States have outpaced the scientific evidence about its potential benefits and risks. In particular there has been growing concern about an increase in the number of middle-aged and older men using testosterone and the lack of scientific data on the effect it may have on aging males. Studies of testosterone replacement therapy in older men have generally been of short duration, involving small numbers of participants and often lacking adequate controls. Testosterone and Aging weighs the options of future research directions, examines the risks and benefits of testosterone replacement therapy, assesses the potential public health impact of such therapy in the United States, and considers ethical issues related to the conduct of clinical trials. Testosterone therapy remains an attractive option to many men even as speculation abounds regarding its potential.
Author: Malcolm Carruthers, MD
Publisher: Xlibris Corporation
Published: 2016-03-09
Total Pages: 208
ISBN-13: 1514449110
DOWNLOAD EBOOK →This is a controversial account of why, because of the barriers to testosterone action in the body, men can have normal levels of testosterone but still have life-, love-, and health-wrecking symptoms of testosterone deficiency which need treatment. The deficiency is increasingly being linked to common and serious medical conditions such as obesity, diabetes, heart and circulatory disorders, and even Alzheimers disease. This has clearly been shown by the authors pioneering research publications as well as those of other colleagues and researchers worldwide. However, in the majority of cases, they are often denied this because of the lack of understanding of the medical profession and other authorities regulating the treatment. This is a wake-up call to both doctors and patients alike to treat the symptoms of testosterone deficiency and related conditions with what the author argues is the most effective, safest, and economic form of preventive medicine of the twenty-first century.
Author: Joseph P. Alukal
Publisher: Springer Nature
Published: 2020-10-15
Total Pages: 280
ISBN-13: 3030544826
DOWNLOAD EBOOK →This book outlines the approach to comprehensive men’s health deployed at three of the most successful American men’s health centers. It demonstrates the ways in which multidisciplinary care allows patients to easily access their doctors via coordination of care, same day add-on visits, and streamlining of office logistics such as sharing of charts, reports, and results. Guiding readers in establishing an evidence-based, multidisciplinary approach to the management of male patients of all ages, this volume shows how prevention, rapid intervention, cost efficiency, and coordinated care are at the forefront of a health center’s care strategy. The authors of this volume are thought leaders in the disciplines of cardiology, gastroenterology, dermatology, psychiatry, and preventative medicine. Design and Implementation of the Modern Men’s Health Center: A Multidisciplinary Approach enables urologists, medical subspecialists, and surgical subspecialists to both manage basic patient issues and also to understand how multidisciplinary care enables the success of a men’s health center.
Author: Trevor Jones
Publisher:
Published: 2013
Total Pages: 181
ISBN-13: 0199675325
DOWNLOAD EBOOK →Author: John P. Mulhall
Publisher: Cambridge University Press
Published: 2013-02-21
Total Pages: 365
ISBN-13: 1107012120
DOWNLOAD EBOOK →Written by international authorities, this book is aimed at clinicians dealing with male patients rendered infertile by cancer therapy.
Author: Franck Mauvais-Jarvis
Publisher: Springer
Published: 2017-12-08
Total Pages: 627
ISBN-13: 3319701789
DOWNLOAD EBOOK →The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.
Author: Wayne J.G. Hellstrom
Publisher: Springer Science & Business Media
Published: 2012-11-28
Total Pages: 154
ISBN-13: 1627031790
DOWNLOAD EBOOK →Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies explores the difficulties around the diagnosis and treatment of androgen deficiency. The text examines the available evidence concerning the diagnosis and treatment of men with low testosterone. It also examines controversies in the identification and management of these men. While the information contained within will be of use to those who specialize in androgen deficiency and sexual medicine, the scope of the book will serve as a source of basic information about testosterone replacement and as a source of reasoned analysis of the controversies surrounding testosterone replacement in the aging male. Physicians and physician extenders will be able to apply evidence management principles to the evaluation and treatment of men with testosterone deficiency; supported by the most recent practice guidelines available. The authors represent a select group of physicians with expertise in androgen deficiency and replacement. Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies will be of great value to all physicians and physician extenders who deliver health care to men of all ages.
Author: Karin Rådholm
Publisher: Linköping University Electronic Press
Published: 2015-09-11
Total Pages: 78
ISBN-13: 9175190303
DOWNLOAD EBOOK →Background The part of the population that belongs to the oldest-old (ages 80 years or older) increases rapidly, worldwide. Cardiovascular disease (CVD) is the leading cause of death and disease burden globally. Multimorbidity is common in old age and stroke, diabetes mellitus (DM) and atrial fibrillation (AF) are strongly associated with age. Cardiovascular risk factors are well studied and documented in younger and middle ages, but not as well in old and frail individuals. Therefore, preventive treatment choices are mostly based on evidence for younger patients. The aim of this thesis was to explore age and other aspects of cardiovascular risk factors; AF, hypertension and DM, in relation to comorbidity, cardiovascular outcome and mortality. Methods This thesis was based on four different studies: The ELSA85 study of 85 years old in Linköping, SwedenThe international, multicentre, randomised controlled INTERACT2 trial of spontaneous intracranial haemorrhage (ICH), mean age 64 years.The prospective SHADES study of nursing home residents, mean age 85 years.The prospective, national SWE-diadep study of dispensed antidiabetics, antidepressantsand prevalent myocardial infarction (MI) in 45-84 years old. Data was obtained from questionnaires (ELSA85, INTERACT2), medical records and medical examination (ELSA85, INTERACT2, SHADES), and national registers (SWE-Diadep). Results The ELSA85 study showed that 16% (n=53) had an ECG showing AF. There was an increased hazard ratio (HR) for all-cause mortality in participants with AF at baseline, at 90 years of age (HR 1.59, 95% [Confidence Interval] CI 1.04-2.44) adjusted for sex. This increase in HR did not persist when adjusted for congestive heart failure (CHF). In the INTERACT2 study, increasing age was associated with increasing frequency of death or dependency (odds ratio [OR] 4.36, 95% [CI] 3.12-6.08 for >75 years vs <52 years, p value for trend <0.001). The SHADES study showed that participants with Systolic blood pressure (SBP) <120 mmHg had an increased HR for mortality (1.56, 95% CI, 1.08–2.27; p=0.019) but there were no differences between SBP groups 140–159 mmHg and ?160 mmHg compared with the reference group SBP 120–139 mmHg. SBP decreased during the prospective study period. In the SWE-diadep study, individuals with antidiabetics and antidepressants combined had a greater HR for MI compared to the reference of no antidiabetics or antidepressants, mostly so in women aged 45-64 years (HR 7.4, 95% CI: 6.3-8.6). Conclusion Risk factors for CVDs in elderly differ from cardiovascular risk factors in middle aged individuals an
