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Testing Fate

Author: Shelley Z. Reuter

Publisher: U of Minnesota Press

Published: 2016-08-17

Total Pages: 366

ISBN-13: 1452951896

In today’s world, responsible biocitizenship has become a new way of belonging in society. Individuals are expected to make “responsible” medical choices, including the decision to be screened for genetic disease. Paradoxically, we have even come to see ourselves as having the right to be responsible vis-à-vis the proactive mitigation of genetic risk. At the same time, the concept of genetic disease has become a new and powerful way of defining the boundaries between human groups. Tay-Sachs, an autosomal recessive disorder, is a case in point—with origins in the period of Eastern European Jewish immigration to the United States and United Kingdom that spanned the late nineteenth and early twentieth centuries, it has a long and fraught history as a marker of Jewish racial difference. In Testing Fate, Shelley Z. Reuter asks: Can the biocitizen, especially one historically defined as a racialized and pathologized Other, be said to be exercising authentic, free choice in deciding whether to undertake genetic screening? Drawing on a range of historical and contemporary examples—doctors’ medical reports of Tay-Sachs since the first case was documented in 1881, the medical field’s construction of Tay-Sachs as a disease of Jewish immigrants, YouTube videos of children with Tay-Sachs that frame the disease as tragic disability avoidable through a simple genetic test, and medical malpractice suits since the test for the disease became available—Reuter shows that true agency in genetic decision-making can be exercised only from a place of cultural inclusion. Choice in this context is in fact a kind of unfreedom—a moral duty to act that is not really agency at all.

Am I My Genes?

Author: Robert L. Klitzman M.D.

Publisher: Oxford University Press

Published: 2012-03-01

Total Pages: 376

ISBN-13: 0190207671

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In the fifty years since DNA was discovered, we have seen extraordinary advances. For example, genetic testing has rapidly improved the diagnosis and treatment of diseases such as Huntington's, cystic fibrosis, breast cancer, and Alzheimer's. But with this new knowledge comes difficult decisions for countless people, who wrestle with fear about whether to get tested, and if so, what to do with the results. Am I My Genes? shows how real individuals have confronted these issues in their daily lives. Robert L. Klitzman interviewed 64 people who faced Huntington's Disease, breast and ovarian cancer, or Alpha-1 antitrypsin deficiency. The book describes--often in the person's own words--how each has wrestled with the vast implications that genetics has for their lives and their families. Klitzman shows how these men and women struggle to make sense of their predicament and its causes. They confront a series of quandaries--whether to be tested; whether to disclose their genetic risks to parents, siblings, spouses, offspring, friends, doctors, insurers, employers, and schools; how to view and understand themselves and their genetics; what treatments, if any, to pursue; whether to have children, adopt, screen embryos, or abort; and whether to participate in genetic communities. In the face of these uncertainties, they have tried to understand these tests and probabilities, avoid fatalism, anxiety, despair, and discrimination, and find hope, meaning, and a sense of wholeness. Forced to wander through a wilderness of shifting sands, they chart paths that many others may eventually follow. Klitzman captures here the voices of pioneers, some of the first to encounter the personal dilemmas introduced by modern genetics. Am I My Genes? is an invaluable account of their experience, one that will become all the more common in the coming years. "An extraordinary exploration...probing the many roles and implications of genetics in our lives today.... Filled with astonishing insights, this riveting book is vital reading for us all." --Paula Zahn "Klitzman lucidly discusses the moral and psychological complexities that come in the wake of genetic testing.... An important book for anyone who has the genes for pathology, which is all of us, and I recommend it highly." --Kay Redfield Jamison, author of An Unquiet Mind "An illuminating voyage through the medical, familial and existential quandaries faced by those of us at genetic risk." --Thomas H. Murray, President and CEO, The Hastings Center

Test of Fate

Author: Lynn Englund

Publisher: Lulu.com

Published: 2009-11-02

Total Pages: 317

ISBN-13: 0557050669

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The second book in the of Fate series, Test of Fate, continues the story of Evan Masters and Carla Jean C.J. MacFarlane. Set two years after Miracle of Fate, this novel follows Evan and C.J. continuing to explore life together as a couple very much in love. They decide to start a charitable foundation to broaden their reach and give back some of the good fortune they share. Not having any real experience in the non-profit arena, they hire a young woman named Jennifer Truman to run the foundation. Decisions about their future come to the forefront as C.J. struggles with Evan's desire to have children. With Evan at her side, she continues to search for her true place in the world. Filled with romance, drama, suspense and humor, Test of Fate allows the reader greater insight into Evan and C.J. as captivating, yet very much human, characters. When their relationship is subjected to the ultimate test, will their love be enough to survive?

Mapping Fate

Author: Alice Wexler

Publisher: Univ of California Press

Published: 1996-12-30

Total Pages: 354

ISBN-13: 9780520207417

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Wexler tells the story of a family at risk for Huntington's disease, a hereditary, incurable, fatal disorder from which her own mother died. This graceful and eloquent account goes beyond the specifics of the disease to explore the dynamics of family secrets, of living at risk, and the drama and limits of biomedical research. Photos.

Tempting Fate

Author: Paul C. Avey

Publisher: Cornell University Press

Published: 2019-11-15

Total Pages: 252

ISBN-13: 1501740393

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Why would countries without nuclear weapons even think about fighting nuclear-armed opponents? A simple answer is that no one believes nuclear weapons will be used. But that answer fails to consider why nonnuclear state leaders would believe that in the first place. In this superb unpacking of the dynamics of conflict under conditions of nuclear monopoly, Paul C. Avey argues that the costs and benefits of using nuclear weapons create openings that weak nonnuclear actors can exploit. Tempting Fate uses four case studies to show the key strategies available to nonnuclear states: Iraqi decision-making under Saddam Hussein in confrontations with the United States; Egyptian leaders' thinking about the Israeli nuclear arsenal during wars in 1969–70 and 1973; Chinese confrontations with the United States in 1950, 1954, and 1958; and a dispute that never escalated to war, the Soviet-United States tensions between 1946 and 1948 that culminated in the Berlin Blockade. Those strategies include limiting the scope of the conflict, holding chemical and biological weapons in reserve, seeking outside support, and leveraging international non-use norms. Counterintuitively, conventionally weak nonnuclear states are better positioned to pursue these strategies than strong ones, so that wars are unlikely when the nonnuclear state is powerful relative to its nuclear opponent. Avey demonstrates clearly that nuclear weapons cast a definite but limited shadow, and while the world continues to face various nuclear challenges, understanding conflict in nuclear monopoly will remain a pressing concern for analysts and policymakers.

Testing Fate

Author: Belinda Boring

Publisher: Createspace Independent Publishing Platform

Published: 2013-05-15

Total Pages: 0

ISBN-13: 9781483948591

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Nothing burns as bright as the flames of the refiner's fire. Moments after hearing the Council sentence her enemy to life imprisonment for attempted murder and illegal use of magic, Darcy is whisked away by the Fates-accused of tampering with destiny. The cherished dream she shared with Mason has been called into question, placing doubt about whether they are actually true mates. To resolve it, a price must be paid-the Heart or Death-a grueling series of tests designed to reveal a person's worth. The stakes are high and Darcy finds herself facing the unknown in conditions that leave her more vulnerable than she's ever been. Separated from Mason and her Pack, with Devlin as her only companion, she is pushed to her very limits. She must succeed-or lose everything. Will she crumble under the pressure or emerge stronger for testing fate?

Improbable Destinies

Author: Jonathan B. Losos

Publisher: Penguin

Published: 2017-08-08

Total Pages: 384

ISBN-13: 0399184937

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A major new book overturning our assumptions about how evolution works Earth’s natural history is full of fascinating instances of convergence: phenomena like eyes and wings and tree-climbing lizards that have evolved independently, multiple times. But evolutionary biologists also point out many examples of contingency, cases where the tiniest change—a random mutation or an ancient butterfly sneeze—caused evolution to take a completely different course. What role does each force really play in the constantly changing natural world? Are the plants and animals that exist today, and we humans ourselves, inevitabilities or evolutionary flukes? And what does that say about life on other planets? Jonathan Losos reveals what the latest breakthroughs in evolutionary biology can tell us about one of the greatest ongoing debates in science. He takes us around the globe to meet the researchers who are solving the deepest mysteries of life on Earth through their work in experimental evolutionary science. Losos himself is one of the leaders in this exciting new field, and he illustrates how experiments with guppies, fruit flies, bacteria, foxes, and field mice, along with his own work with anole lizards on Caribbean islands, are rewinding the tape of life to reveal just how rapid and predictable evolution can be. Improbable Destinies will change the way we think and talk about evolution. Losos's insights into natural selection and evolutionary change have far-reaching applications for protecting ecosystems, securing our food supply, and fighting off harmful viruses and bacteria. This compelling narrative offers a new understanding of ourselves and our role in the natural world and the cosmos.

The Science of Fate

Author: Hannah Critchlow

Publisher: Hodder & Stoughton

Published: 2019-05-02

Total Pages: 256

ISBN-13: 1473659302

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**THE SUNDAY TIMES BESTSELLER** 'A truly fascinating - if unnerving - read' DAILY TELEGRAPH 'Acute, mind-opening, highly accessible - this book doesn't just explain how our lives might pan out, it helps us live better' BETTANY HUGHES 'A humane and highly readable account of the neuroscience that underpins our ideas of free will and fate' PROFESSOR DAVID RUNCIMAN *** So many of us believe that we are free to shape our own destiny. But what if free will doesn't exist? What if our lives are largely predetermined, hardwired in our brains - and our choices over what we eat, who we fall in love with, even what we believe are not real choices at all? Neuroscience is challenging everything we think we know about ourselves, revealing how we make decisions and form our own reality, unaware of the role of our unconscious minds. Did you know, for example, that: * You can carry anxieties and phobias across generations of your family? * Your genes and pleasure and reward receptors in your brain will determine how much you eat? * We can sniff out ideal partners with genes that give our offspring the best chance of survival? Leading neuroscientist Hannah Critchlow draws vividly from everyday life and other experts in their field to show the extraordinary potential, as well as dangers, which come with being able to predict our likely futures - and looking at how we can alter what's in store for us. Lucid, illuminating, awe-inspiring The Science of Fate revolutionises our understanding of who we are - and empowers us to help shape a better future for ourselves and the wider world.

Twisting Fate

Author: Pamela Munster

Publisher: The Experiment

Published: 2018-09-25

Total Pages: 273

ISBN-13: 1615194789

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From a woman who’s made her living researching breast cancer—and who lived through it herself—a personal yet practical guide to the medical and emotional facets of this life-changing diagnosis A leading oncologist at the University of California San Francisco, Dr. Pamela Munster has advised thousands of women on how to cope with the realities of breast cancer, from diagnosis through treatment and recovery. But her world turned upside down when, at forty-eight years old and in otherwise perfect health, she got a call saying that her own mammogram showed “irregularities.” That single word thrust her into a wholly new role—as patient, and not only that of cancer but of the feared BRCA gene mutation as well. Suddenly, she realized that being a true “expert” in a disease was far beyond the scope of her medical training, and that she had a lot to learn if she wanted to hold onto her precious life. Weaving together her personal story with groundbreaking research on BRCA—responsible for breast cancer and many other inherited cancers affecting both women and men—Twisting Fate is an inspiring guide to living with the uncertainties of cancer. With authority, insight, and compassion, Dr. Munster uses her voice to create a safe space for genuine healing and honesty in a world otherwise too-often dominated by fear—and she is living proof of how important it is to embrace all the twists and turns of fate.