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Targeted Molecular Imaging

Author: Michael J. Welch

Publisher: Taylor & Francis

Published: 2012-02-24

Total Pages: 378

ISBN-13: 1439841969

Targeted Molecular Imaging covers the development of novel diagnostic approaches that use an imaging probe and agent to noninvasively visualize cellular processes in normal and disease states. It discusses the concept, development, preclinical studies, and, in many cases, translation to the clinic of targeted imaging agents. The many case studies t

Nuclear Medicine in Oncology

Author: Gang Huang

Publisher: Springer

Published: 2019-06-11

Total Pages: 346

ISBN-13: 9811374589

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This book introduces molecular imaging and Target Therapy in various cancers. The first part is the subjects and primary focused on the basics of nuclear physics, radiation dosimetry, nuclear medicine equipment and small animal imaging equipment. The second part is about the radiopharmaceutical and commonly used clinical radiopharmaceuticals, including positron emission imaging agent, single photon emission imaging agent, and radionuclide therapy agents as well as their radioactive preparation, quality control, and a brief clinical application were included. Also, this part introduces a number of new imaging agents which were potential value of clinical applications. In the third part, the clinical application of the conventional imaging agent 18F-FDG in different tumors and neurodegenerative diseases and 18F-Dopa imaging in the nervous system are discussed. Besides the clinical applications of 99mTc labeled radiopharmaceuticals in parathyroid disease, coronary heart disease, myocardial infarction, sentinel lymph node, metastatic bone tumors, liver and gallbladder disease in children are introduced. Finally, the applications of radionuclide 131I on treatments of Graves' disease and differentiated thyroid cancer and metastases are investigated respectively. This book is a useful reference for professionals engaged in nuclear medicine and clinical research, including clinical nuclear medicine physicians, nuclear medicine engineers and nuclear medicine pharmacists.

Clinical Molecular Diagnostics

Author: Shiyang Pan

Publisher: Springer Nature

Published: 2021-07-08

Total Pages: 889

ISBN-13: 9811610371

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This book covers the discovery of molecular biomarkers, the development of laboratory testing techniques and their clinical applications, focusing on basic research to clinical practice. It introduces new and crucial knowledge and ethics of clinical molecular diagnosis. This book emphasizes the applications of clinical molecular diagnostic test on health management, especially from different diseased organs. It lets readers to understand and realize precision healthcare.

Targeted Molecular Imaging in Oncology

Author: E. Edmund Kim

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 302

ISBN-13: 1475735057

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This volume is unique in reporting on strategies for the application of molecular targeted imaging agents such as antibodies, peptides, receptors and contrast agents in the biologic grading of tumors, differential diagnosis of tumors, prediction of therapeutic response and monitoring tumor response to treatment. It also includes updated information on the imaging of tumor angiogenesis, hypoxia, apoptosis and gene delivery as well as expression in the understanding and utility of tumor molecular biology for better cancer management.

Molecular Imaging

Author: Brian D. Ross

Publisher: Academic Press

Published: 2021-08-03

Total Pages: 1872

ISBN-13: 0128163879

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The detection and measurement of the dynamic regulation and interactions of cells and proteins within the living cell are critical to the understanding of cellular biology and pathophysiology. The multidisciplinary field of molecular imaging of living subjects continues to expand with dramatic advances in chemistry, molecular biology, therapeutics, engineering, medical physics and biomedical applications. Molecular Imaging: Principles and Practice, Volumes 1 and 2, Second Edition provides the first point of entry for physicians, scientists, and practitioners. This authoritative reference book provides a comprehensible overview along with in-depth presentation of molecular imaging concepts, technologies and applications making it the foremost source for both established and new investigators, collaborators, students and anyone interested in this exciting and important field. The most authoritative and comprehensive resource available in the molecular-imaging field, written by over 170 of the leading scientists from around the world who have evaluated and summarized the most important methods, principles, technologies and data Concepts illustrated with over 600 color figures and molecular-imaging examples Chapters/topics include, artificial intelligence and machine learning, use of online social media, virtual and augmented reality, optogenetics, FDA regulatory process of imaging agents and devices, emerging instrumentation, MR elastography, MR fingerprinting, operational radiation safety, multiscale imaging and uses in drug development This edition is packed with innovative science, including theranostics, light sheet fluorescence microscopy, (LSFM), mass spectrometry imaging, combining in vitro and in vivo diagnostics, Raman imaging, along with molecular and functional imaging applications Valuable applications of molecular imaging in pediatrics, oncology, autoimmune, cardiovascular and CNS diseases are also presented This resource helps integrate diverse multidisciplinary concepts associated with molecular imaging to provide readers with an improved understanding of current and future applications

Molecular Imaging and Targeted Therapy

Author: Shankar Vallabhajosula

Publisher: Springer Nature

Published: 2023-03-31

Total Pages: 719

ISBN-13: 3031232054

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This book, now published in its second edition, covers a wide range of topics relating to the use of radiopharmaceuticals. The basics of nuclear chemistry, radiochemistry, and radiopharmacology are considered in detail, regulatory issues are reviewed, and potential applications in drug development, translational medicine, clinical diagnostics, and targeted therapy are discussed. Compared with the first edition, the chapters on targeted therapy with alpha- and beta-emitting radiopharmaceuticals and theranostics are completely new. Other chapters have been updated and revised as necessary. Radioisotope-based molecular imaging probes (radiopharmaceuticals) provide unprecedented insights into biochemistry and function in both normal and diseased states of living systems, with unbiased in vivo measurements of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology, including functional magnetic resonance imaging, can provide such high sensitivity and specificity at a tracer level. This book, written by an experienced radiochemist and scientist, offers valuable insights into the full range of applications of this technology.

Molecular Imaging

Author: Ralph Weissleder

Publisher: PMPH-USA

Published: 2010

Total Pages: 1384

ISBN-13: 9781607950059

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The field of molecular imaging of living subjects have evolved considerably and have seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: "Molecular Imaging technologies", "Chemistry", "Molecular Imaging in Cell and Molecular Biology", "Applications of Molecular Imaging", "Molecular Imaging in Drug Evaluation" with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.

Targeted Molecular Imaging

Author: E. Edmund Kim

Publisher: Springer

Published: 2011-05-27

Total Pages:

ISBN-13: 9781441908001

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Targeted Molecular Imaging: Principles and Applications presents the basic science behind personalized cancer medicine and accelerating drug approval from bench to clinic through the application of molecular imaging science and technology. Topics to be covered include the application of gamma scintigraphy (PET and SPECT) in oncology, the effect of contrast agents in PET/CT, radiation dosimetric determination for radiotheranostic agents, imaging technology in drug development, validation of imaging agents on new molecular targets, and economic potential for the development of molecular targeting agents and the process and requirements for FDA compliance.

Molecular Imaging in Oncology

Author: Martin G. Pomper

Publisher: CRC Press

Published: 2008-10-13

Total Pages: 762

ISBN-13: 1000654400

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With molecular imaging becoming one the fastest growing topics in medical schools, Informa Healthcare presents Molecular Imaging in Oncology, the first comprehensive reference on molecular imaging in oncology.Giving clinicians and researchers a greater understanding of the current field, this text covers:instrumentation and techniquescancer imaging

Biotechnology Products in Everyday Life

Author: Menka Khoobchandani

Publisher: Springer

Published: 2018-11-03

Total Pages: 250

ISBN-13: 3319923994

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This book explores a sampling of the most powerful and enterprising efforts to achieve biotechnological goals by means of various interdisciplinary approaches. From the fabrication of extremely small units to achieve specific objectives through nano-bio-technology, to devices with artificial intelligence, gene therapy for cerebrovascular anomalies, biodegradable plastics, the use of phyto-stem cells in cosmetology, CarT cell immune therapy, targeted therapies for cancer, 3D printed bones developed by the University of Wollongong in Australia, the sickle cell chip developed by IIT Bombay, and innovative sustainable energy solutions, the book includes a colorful spectrum of reviews on current and future biotech products. Gathering contributions by an international team of researchers, this book offers its audience, and particularly younger readers, revealing information on current and upcoming smart technologies.