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Genetics, Neurology, Behavior, and Diet in Parkinson's Disease

Author: Colin R Martin

Publisher: Academic Press

Published: 2020-08-13

Total Pages: 764

ISBN-13: 0128159510

Genetics, Neurology, Behavior, and Diet in Parkinson's Disease: The Neuroscience of Parkinson’s Disease, Volume 2 provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. It fills a much-needed gap as a "one-stop" synopsis of everything to do with the neurology and neuroscience related to Parkinson’s disease—from chemicals and cells to individuals. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field. Offers the most comprehensive coverage of a broad range of topics related to Parkinson's disease Serves as a foundational collection for neuroscientists and neurologists on the biology of disease and brain dysfunction Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations Serves as a "one-stop" source for everything you need to know about Parkinson’s disease

Synucleins

Author: Andrei Surguchov

Publisher: BoD – Books on Demand

Published: 2020-04-08

Total Pages: 98

ISBN-13: 1789845653

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Neurodegenerative diseases are debilitating conditions that result in degeneration and death of nerve cells. A significant group of these diseases is the synucleinopathies, which are characterized by the accumulation of aggregates of alpha-synuclein in neurons, nerve fibers, or glial cells. There are three main types of synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. Synucleins are small, naturally unfolded proteins prone to aggregate and form intracellular inclusions, which impair normal cellular functions. This book presents new data on synuclein aggregation and its effect on cholesterol transport. It also discusses the role of genetic contribution to these diseases and approaches to inhibition of synuclein aggregation.

Synuclein and the Coelacanth

Author: James M. Gruschus

Publisher: Academic Press

Published: 2021-01-31

Total Pages: 314

ISBN-13: 0323899684

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Most neurodegenerative diseases have animal parallels such as Alzheimer’s in chimpanzees, multiple sclerosis in macaques, Lou Gehrig’s disease in dogs, but nothing like Parkinson’s has ever been seen in any species but humans. Synuclein and the Coelacanth: The Molecular and Evolutionary Origins of Parkinson's Disease delves into the causes of Parkinson’s disease and how the evolution of the human brain has left us uniquely vulnerable. Genetic risk factors, environmental toxins, and neuroanatomy are woven together in a multidisciplinary discussion that ranges from subatomic physics to socioeconomics. Connections between neurodegenerative disease, neural pathways, and innate immunity are explored. Finally, the author discusses new therapeutic agents are being developed that hope to go beyond just treating the symptoms of Parkinson’s and actually halt the disease. Proposes a new hypothesis on the origins of Parkinson’s disease Examines genetic risk factors, environmental toxins, and neuroanatomy of PD Highlights new therapeutic treatment options in development for patients

Synucleins—Advances in Research and Application: 2013 Edition

Author:

Publisher: ScholarlyEditions

Published: 2013-06-21

Total Pages: 161

ISBN-13: 1481680609

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Synucleins—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about alpha-Synuclein. The editors have built Synucleins—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about alpha-Synuclein in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Synucleins—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Synucleins—Advances in Research and Application: 2012 Edition

Author:

Publisher: ScholarlyEditions

Published: 2012-12-26

Total Pages: 182

ISBN-13: 1464998957

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Synucleins—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Synucleins. The editors have built Synucleins—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Synucleins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Synucleins—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Synucleins: Advances in Research and Application: 2011 Edition

Author:

Publisher: ScholarlyEditions

Published: 2012-01-09

Total Pages: 128

ISBN-13: 1464928452

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Synucleins: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Synucleins. The editors have built Synucleins: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Synucleins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Synucleins: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The Protein Alpha-Synuclein: Its Normal Role (in Neurons) and its Role in Disease

Author: Fredric P. Manfredsson

Publisher: Frontiers Media SA

Published: 2020-03-25

Total Pages: 151

ISBN-13: 2889636100

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Metal Related Neurodegenerative Disease

Author:

Publisher: Academic Press

Published: 2013-11-07

Total Pages: 443

ISBN-13: 0124105351

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This issue reviews the role of metals in neurodegenerative diseases; including Parkinson’s and Huntington’s disease; restless leg syndrome and NBIA disorders; and Wilson’s disease and manganese and calcium accumulation disorders. An update on advances in neuroimaging and pathology of metal related disease is also presented. This volume of International Review of Neurobiology brings together cutting-edge research on metal related neurodegenerative disease It reviews the role of metals in neurodegenerative diseases, including Parkinson’s and Huntington’s disease; restless leg syndrome and NBIA disorders; and Wilson’s disease and manganese and calcium accumulation disorders An update on advances in neuroimaging and pathology of metal related disease is also presented

Frontiers in Guided Wave Optics and Optoelectronics

Author: Bishnu Pal

Publisher: BoD – Books on Demand

Published: 2010-02-01

Total Pages: 694

ISBN-13: 9537619826

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As the editor, I feel extremely happy to present to the readers such a rich collection of chapters authored/co-authored by a large number of experts from around the world covering the broad field of guided wave optics and optoelectronics. Most of the chapters are state-of-the-art on respective topics or areas that are emerging. Several authors narrated technological challenges in a lucid manner, which was possible because of individual expertise of the authors in their own subject specialties. I have no doubt that this book will be useful to graduate students, teachers, researchers, and practicing engineers and technologists and that they would love to have it on their book shelves for ready reference at any time.

International Review of Cell and Molecular Biology

Author: Kwang W. Jeon

Publisher: Academic Press

Published: 2009-02-24

Total Pages: 371

ISBN-13: 0080923313

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International Review of Cell & Molecular Biology presents current advances and comprehensive reviews in cell biology—both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation and cell transformation and growth. Authored by some of the foremost scientists in the field Provides up-to-date information and directions for future research Valuable reference material for advanced undergraduates, graduate students and professional scientists