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Surface Modification of Nanoparticles for Targeted Drug Delivery

Author: Yashwant V Pathak

Publisher: Springer

Published: 2019-03-11

Total Pages: 499

ISBN-13: 3030061159

This unique book is the only one to discuss various new techniques developed to enhance the application of nanoparticulate drug delivery systems using surface modification of nanoparticles. The understanding of the surface characteristics nano-particles is growing significantly with the advent of new analytical techniques. Polymer chemistry is contributing to the development of many new versatile polymers which have abilities to accommodate many different, very reactive chemical groups, and can be used as a diagnostic tool, for better targeting, for more effective therapeutic results as well as for reducing the toxic and side effects of the drugs. Surface modification of such polymeric nanoparticles has been found by many scientists to enhance the application of nanoparticles and also allows the nano particles to carry specific drug molecule and disease /tumor specific antibodies which refine and improve drug delivery. Surface Modification of Nanoparticles for Targeted Drug Delivery is a collection essential information with various applications of surface modification of nanoparticles and their disease specific applications for therapeutic purposes.

Synthesis, Functionalization and Surface Treatment of Nanoparticles

Author: Marie-Isabelle Baraton

Publisher:

Published: 2003

Total Pages: 340

ISBN-13:

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Synthesis, Functionalization and Surface Treatment of Nanoparticles is an area of crucial importance in the emerging field of nanotechnology. Controlling the surface chemical composition and mastering its modification at the nanometer scale are critical issues for high-added value applications involving nanoparticles. The basic applications of surface functionalization range from altering the wetting or adhesion characteristics and improving the nanoparticles dispersion in matrices to enhancing the catalytic properties and ordering the interfacial region, and such. The creation of specific surface sites on nanoparticles for selective molecular attachment is considered a promising approach for their applications in nanofabrication, nanopatterning, selfassembly, nanosensors, bioprobes, drug delivery, pigments, photocatalysis, LEDs, etc. This book presents novel and improved synthesis methods and approaches for controlling and functionalizing the nanoparticle surfaces to enhance the overall performance of the nanoparticles for targeted applications.

Role of Novel Drug Delivery Vehicles in Nanobiomedicine

Author: Rajeev K. Tyagi

Publisher: BoD – Books on Demand

Published: 2020-02-26

Total Pages: 196

ISBN-13: 1789239850

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Medical Nanotechnology and Nanomedicine introduces non-experts to the world of nanomedicine and its evolving organizational infrastructure. Considering the fluid nature of nano breakthroughs and the delicate balance between benefits and consequences as they apply to medicine, readers at all levels will gain a practical, understandable base of information on these developments so that they may take the greatest advantage of them. This practical reference investigates the impact of nanotechnology on applications in medicine and biomedical sciences, and the broader societal and economic effects. Eschewing technological details, it focuses on enhancing awareness of the business, regulatory, and administrative aspects of medical applications. It gives readers a critical, balanced, and realistic evaluation of existing nanomedicine developments and future prospects and provides an ideal foundation upon which to plan and make decisions.

Nanoparticulate Drug Delivery Systems

Author: Deepak Thassu

Publisher: CRC Press

Published: 2007-03-30

Total Pages: 373

ISBN-13: 1420008447

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With the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. Nanoparticulate Drug Delivery Systems addresses the scientific methodologies, formulation, processing, applications, recent trends, and e

Nanotechnology for Cancer Therapy

Author: Mansoor M. Amiji

Publisher: CRC Press

Published: 2006-12-19

Total Pages: 840

ISBN-13: 1420006630

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While simultaneous breakthroughs occurring in molecular biology and nanoscience/technology will ultimately revolutionize all of medicine, it is with our efforts to prevent, diagnose, and treat cancer that many of the most dramatic advances will occur. In support of this potential, the U.S. National Cancer Institute (NCI) established the Alliance fo

Silk-based Drug Delivery Systems

Author: Elia Bari

Publisher: Royal Society of Chemistry

Published: 2020-10-07

Total Pages: 243

ISBN-13: 1788017722

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Covering spider silk and silk worm cocoons, the editors elucidate the extraction, structure and properties of silk sericin and silk fibroin.

Nanoscale Materials in Targeted Drug Delivery, Theragnosis and Tissue Regeneration

Author: Sudesh Kumar Yadav

Publisher: Springer

Published: 2016-06-04

Total Pages: 172

ISBN-13: 9811008183

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This book is the first of its kind to offer a comprehensive and up-to-date discussion of the use of nanoscale materials for biomedical applications, with a particular focus on drug delivery, theragnosis and tissue regeneration. It also describes in detail the methods used in the preparation of nanoparticles. Response of nanoparticles in biological systems are also explored. Nanotechnology has led to the advent of a new field, nanomedicine, which focuses on the use of nanomaterials as drug-delivery vehicles to develop highly selective and effective drugs. The combination of molecular imaging and nanotechnology has produced theragnostic nanoparticles, which allow the simultaneous detection and monitoring of diseases. Nanotechnology can also be combined with biomaterials to create scaffolds for tissue regeneration. Further, significant advances have been made in the areas of drug delivery, theragnostic nanoparticles and tissue regeneration materials. Some nanomedicines and tissue regeneration materials are already commercially available, while others are undergoing clinical trials, and promising results have been documented. Despite the rapid advances in nanomedicine, there is a relative dearth of literature on the biomedical applications of nanoscale materials.

Nanoparticles for Drug Delivery

Author: K. S. Joshy

Publisher: Springer Nature

Published: 2021-06-21

Total Pages: 214

ISBN-13: 9811621195

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This book introduces the reader to drug delivery with specific emphasis on the use of nanoparticles. It covers properties, characterization, and preparation of different types of nanoparticles and discusses recent advances in their structural design and biomedical application, as well as the issues and challenges associated with their design and use. Some of the topics covered include the potential application of nanoparticles in biomedical fields, hazards associated with use of nanoparticles for drug delivery, size-dependent factors in drug delivery applications, different organic, inorganic and their hybrid systems used in drug delivery, etc. It also highlights use of nanoparticles in controlled and targeted drug delivery, and their application in stimuli-responsive, especially pH-responsive, drug release. Additionally, it also focuses on biomimetic nanoparticles, challenges faced in the designing of nanoparticles for drug delivery in cancer, viral and bacterial diseases. The contents of this volume will be useful to researchers and professionals working on advances in targeted drug delivery systems.

Drug Delivery with Targeted Nanoparticles

Author: Yılmaz Çapan

Publisher: CRC Press

Published: 2021-11-30

Total Pages: 654

ISBN-13: 1000375307

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Nanotechnology has the potential to change every part of our lives. Today, nanotechnology-based products are used in many areas, and one of the most important areas is drug delivery. Nanoparticulate drug delivery systems not only provide controlled delivery of drugs and improved drug solubility but also improve drug efficiency and reduce side effects via targeting mechanisms. However, compared with conventional drug delivery systems, few nanoparticle-based products are on the market and almost all are nontargeted or only passively targeted systems. In addition, obtaining targeted nanoparticle systems is quite complex and requires several evaluation mechanisms. This book discusses the production, characterization, regulation, and currently marketed targeted nanoparticle systems in a broad framework. It provides an overview of targeted nanoparticles’ (i) in vitro characterization, such as particle size, stability, ligand density, and type; (ii) in vivo behavior for different targeting areas, such as tumor, brain, and vagina; and (iii) current advances in this field, including clinical trials and regulation processes.

Organic Materials as Smart Nanocarriers for Drug Delivery

Author: Alexandru Mihai Grumezescu

Publisher: William Andrew

Published: 2018-03-26

Total Pages: 768

ISBN-13: 0128136642

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Organic Materials as Smart Nanocarriers for Drug Delivery presents the latest developments in the area of organic frameworks used in pharmaceutical nanotechnology. An up-to-date overview of organic smart nanocarriers is explored, along with the different types of nanocarriers, including polymeric micelles, cyclodextrins, hydrogels, lipid nanoparticles and nanoemlusions. Written by a diverse range of international academics, this book is a valuable reference for researchers in biomaterials, the pharmaceutical industry, and those who want to learn more about the current applications of organic smart nanocarriers. Explores the most recent molecular- and structure-based applications of organic smart nanocarriers in drug delivery Highlights different smart nanocarriers and assesses their intricate organic structural properties for improving drug delivery Assesses how molecular organic frameworks lead to more effective drug delivery systems