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Story Of Genetics, Development And Evolution, The: A Historical Dialogue

Author: Jekely Gaspar

Publisher: World Scientific

Published: 2017-11-24

Total Pages: 540

ISBN-13: 1786342553

This unique story offers an introductory conversation to genetics, embryology and evolution, taking us on a historical journey of biology through the ages. Using a series of dialogues between the Greek philosopher Democritus and his disciple Alkimus, we travel through time visiting eminent scientists throughout the centuries, from Lazzaro Spallanzani and Theodor Boveri to Francis Crick, Max Perutz and Christiane Nüsslein–Volhard. We find ourselves at the intersection of competing theories in biology and witness the progression from the debunking the theory of spontaneous generation to the mapping of the genome. Attention is given not only to the great successes in the field but also to the equally important and exciting failures. Originally published in Hungarian, The Story of Genetics, Development and Evolution provides a historical background to the life sciences, with complex scientific concepts stripped down and explained carefully for academics and anyone interested in going back to the roots and philosophies of scientific progress. Translated from: Jékely G Master, are you awake? A fictitious dialogue on genetics, development and evolution. 2006, Bratislava: Kalligram Contents: PrefaceAt the HarbourAt the MarketPart One: The Mystery (and Sperm) of Life's OriginsDeux Ex MachinaThe World EggSpontaneous Generation and Meat Broth — Lazzaro SpallanzaniTypes and Rhythms of Embryos — Karl Ernst Von BaerCell From a CellThe Feats of the Sea UrchinPart Two: Chromosomes, Mendelian Factors and EvolutionRoasted CaponThe Immortal GermplasmReduction DivisionA London Pigeon Sale — Thomas Henry HuxleyThe Orchard of EvolutionPeas and Minotaur — William BatesonGalton and MendelTwo Sperm, One Ovum — Theodor BoveriPart Three: The Triumph of GenesTrickster Mendelians — Thomas Hunt MorganSex ChromosomesThe Telltale White EyeGenetic MappingPart Four: Forces and ReactionsThe Mathematics of Life — D'arcy Wentworth ThompsonThe Two-Headed NewtZeus's BeardEvolutionary SynthesisThe Casting Moulds of Genes — Hermann Joseph MullerFronts On the Wings of a Moth — Alfred KühnThe Birth of PatternsPart Five: The Atoms of LifeHormones in Larva BloodOne Gene, One Enzyme — George Wells BeadleThe Protein-GenesThe Principle of Transformation — Oswald Theodore AveryThe Triple Helix — Linus PaulingDNA with AmbrosiaPart Six: Codes and LinksThe Central Dogma — Francis CrickThe Diamond Code of ProteinsThe Genetic CodeA Molecular Lung — Max Ferdinand PerutzSugar-Consuming Bacteria — Jacques MonodPart Seven: Genes in the MortarEpigenesis and Genetics — Conrad Hal WaddingtonA Recipe for Making Mice — Sydney BrennerThe Wiring of a Worm's BrainRecombinant DNAStriped Embryos — Christiane Nüsslein-VolhardOur Worm Ancestors — Detlev ArendtThe Age of Genomics — Eugene KooninPart Eight: Beyond GenesPostcard to ThraceThe Cedar Forest of AbderaThe Philosophy of Biology — Ernst MayrThe Genetics of the BiosphereBiscuits Baked in AshOn the Island of Bensalem — Pál Nagy-Juhász

The Story of Genetics, Development, and Evolution

Author: Gáspár Jékely

Publisher:

Published: 2017

Total Pages: 541

ISBN-13: 9781786342546

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Key Features: Entertaining and didactic style Uses an historical perspective to allow the gradual learning of the subject Conversational structure Synthesizing different disciplines thus providing an integrative understanding of biology

Who We Are and How We Got Here

Author: David Reich

Publisher: Oxford University Press

Published: 2018-03-29

Total Pages: 320

ISBN-13: 0192554387

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The past few years have witnessed a revolution in our ability to obtain DNA from ancient humans. This important new data has added to our knowledge from archaeology and anthropology, helped resolve long-existing controversies, challenged long-held views, and thrown up remarkable surprises. The emerging picture is one of many waves of ancient human migrations, so that all populations living today are mixes of ancient ones, and often carry a genetic component from archaic humans. David Reich, whose team has been at the forefront of these discoveries, explains what genetics is telling us about ourselves and our complex and often surprising ancestry. Gone are old ideas of any kind of racial âpurity.' Instead, we are finding a rich variety of mixtures. Reich describes the cutting-edge findings from the past few years, and also considers the sensitivities involved in tracing ancestry, with science sometimes jostling with politics and tradition. He brings an important wider message: that we should recognize that every one of us is the result of a long history of migration and intermixing of ancient peoples, which we carry as ghosts in our DNA. What will we discover next?

A Troublesome Inheritance

Author: Nicholas Wade

Publisher: Penguin

Published: 2014-05-06

Total Pages: 249

ISBN-13: 0698163796

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Drawing on startling new evidence from the mapping of the genome, an explosive new account of the genetic basis of race and its role in the human story Fewer ideas have been more toxic or harmful than the idea of the biological reality of race, and with it the idea that humans of different races are biologically different from one another. For this understandable reason, the idea has been banished from polite academic conversation. Arguing that race is more than just a social construct can get a scholar run out of town, or at least off campus, on a rail. Human evolution, the consensus view insists, ended in prehistory. Inconveniently, as Nicholas Wade argues in A Troublesome Inheritance, the consensus view cannot be right. And in fact, we know that populations have changed in the past few thousand years—to be lactose tolerant, for example, and to survive at high altitudes. Race is not a bright-line distinction; by definition it means that the more human populations are kept apart, the more they evolve their own distinct traits under the selective pressure known as Darwinian evolution. For many thousands of years, most human populations stayed where they were and grew distinct, not just in outward appearance but in deeper senses as well. Wade, the longtime journalist covering genetic advances for The New York Times, draws widely on the work of scientists who have made crucial breakthroughs in establishing the reality of recent human evolution. The most provocative claims in this book involve the genetic basis of human social habits. What we might call middle-class social traits—thrift, docility, nonviolence—have been slowly but surely inculcated genetically within agrarian societies, Wade argues. These “values” obviously had a strong cultural component, but Wade points to evidence that agrarian societies evolved away from hunter-gatherer societies in some crucial respects. Also controversial are his findings regarding the genetic basis of traits we associate with intelligence, such as literacy and numeracy, in certain ethnic populations, including the Chinese and Ashkenazi Jews. Wade believes deeply in the fundamental equality of all human peoples. He also believes that science is best served by pursuing the truth without fear, and if his mission to arrive at a coherent summa of what the new genetic science does and does not tell us about race and human history leads straight into a minefield, then so be it. This will not be the last word on the subject, but it will begin a powerful and overdue conversation.

The Language of the Genes

Author: Steve Jones

Publisher:

Published: 1993

Total Pages: 280

ISBN-13:

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Commissioned by the BBC to deliver the Reith Lectures in 1991, Steve Jones has used them as the basis for this book which argues that the evolution of our genes may be compared to the evolution of language. This book shows readers how close we are to success in the search for our origins.

A Short History of Medical Genetics

Author: Peter S. Harper

Publisher: Oxford University Press

Published: 2008

Total Pages: 570

ISBN-13: 0195187504

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"This book traces the development of genetics in medicine from the first descriptions of inherited diseases more than 300 years ago to the new applications resulting from mapping and sequencing the human genome. It follows both the scientific and the medical advances, focusing especially on those of the past 50 years, which have seen the field of medical genetics emerge as one of the foremost and most rapidly changing medical specialties, now influencing the whole of medicine. It also examines the ethical challenges faced by those working in the field, and describes some of the past disasters that have resulted from these being ignored, notably the abuses of eugenics and the catastrophic destruction of genetics in Soviet Russia. This is the first book of its kind; it is clearly and simply written, and will be valuable to all those who have an interest or concern in the development of medical genetics, as well as those actually working in the field. Historians and social scientists will likewise find this book an important foundation for future detailed studies, which are urgently needed."--BOOK JACKET.

Evolution in Four Dimensions, revised edition

Author: Eva Jablonka

Publisher: MIT Press

Published: 2014-03-21

Total Pages: 577

ISBN-13: 0262525844

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A pioneering proposal for a pluralistic extension of evolutionary theory, now updated to reflect the most recent research. This new edition of the widely read Evolution in Four Dimensions has been revised to reflect the spate of new discoveries in biology since the book was first published in 2005, offering corrections, an updated bibliography, and a substantial new chapter. Eva Jablonka and Marion Lamb's pioneering argument proposes that there is more to heredity than genes. They describe four “dimensions” in heredity—four inheritance systems that play a role in evolution: genetic, epigenetic (or non-DNA cellular transmission of traits), behavioral, and symbolic (transmission through language and other forms of symbolic communication). These systems, they argue, can all provide variations on which natural selection can act. Jablonka and Lamb present a richer, more complex view of evolution than that offered by the gene-based Modern Synthesis, arguing that induced and acquired changes also play a role. Their lucid and accessible text is accompanied by artist-physician Anna Zeligowski's lively drawings, which humorously and effectively illustrate the authors' points. Each chapter ends with a dialogue in which the authors refine their arguments against the vigorous skepticism of the fictional “I.M.” (for Ipcha Mistabra—Aramaic for “the opposite conjecture”). The extensive new chapter, presented engagingly as a dialogue with I.M., updates the information on each of the four dimensions—with special attention to the epigenetic, where there has been an explosion of new research. Praise for the first edition “With courage and verve, and in a style accessible to general readers, Jablonka and Lamb lay out some of the exciting new pathways of Darwinian evolution that have been uncovered by contemporary research.” —Evelyn Fox Keller, MIT, author of Making Sense of Life: Explaining Biological Development with Models, Metaphors, and Machines “In their beautifully written and impressively argued new book, Jablonka and Lamb show that the evidence from more than fifty years of molecular, behavioral and linguistic studies forces us to reevaluate our inherited understanding of evolution.” —Oren Harman, The New Republic “It is not only an enjoyable read, replete with ideas and facts of interest but it does the most valuable thing a book can do—it makes you think and reexamine your premises and long-held conclusions.” —Adam Wilkins, BioEssays

In The Spirit Of Science: Lectures By Sydney Brenner On Dna, Worms And Brains

Author: Brenner Sydney

Publisher: World Scientific

Published: 2018-09-07

Total Pages: 128

ISBN-13: 9813271752

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In October 2017, Nobel laureate Sydney Brenner (Physiology or Medicine, 2002) gave four lectures on the history of Molecular Biology, its impact on Neuroscience and the great scientific questions that lie ahead.Sydney Brenner has been at the centre of the development of molecular biology, being a key player in shaping the Laboratory for Molecular Biology in Cambridge into a cradle of research, where pioneering and seminal discoveries in the field for over half a century have resulted in more than half a dozen Nobel Prizes.His memory is a treasure trove of the history of the field with innumerable anecdotes on other leading scientists in the past 60 years. These lectures trace the history and recount some of those anecdotes. His interlocutor Terry Sejnowski is the Francis Crick professor at the Salk Institute for Biological Studies and the Laboratory Head of its Computational Neurobiology Laboratory. Terry and Sydney are long-term collaborators and they share many stories and memories.The recorded lectures are the basis for this book. It aims to preserve the history of molecular biology and to also raise scientific questions that have resulted from the work of Sydney, Terry and others. It should be read by everybody who is interested in the generation, history and impact of great ideas as recounted by one of the legends of 20th century science.

From Embryology to Evo-devo

Author: Manfred Dietrich Laubichler

Publisher: MIT Press (MA)

Published: 2007

Total Pages: 592

ISBN-13:

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Historians, philosophers, sociologists, and biologists explore the history of the idea that embryological development and evolution are linked.

Time, Love , Memory

Author: Jonathan Weiner

Publisher: Vintage

Published: 2014-05-14

Total Pages: 322

ISBN-13: 0804153361

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The story of Nobel Prize–winning discoveries regarding the molecular mechanisms controlling the body’s circadian rhythm. How much of our fate is decided before we are born? Which of our characteristics is inscribed in our DNA? Weiner brings us into Benzer's Fly Rooms at the California Institute of Technology, where Benzer, and his asssociates are in the process of finding answers, often astonishing ones, to these questions. Part biography, part thrilling scientific detective story, Time, Love, Memory forcefully demonstrates how Benzer's studies are changing our world view--and even our lives. Jonathan Weiner, winner of the Pulitzer Prize for The Beak of the Finch, brings his brilliant reporting skills to the story of Seymour Benzer, the Brooklyn-born maverick scientist whose study of genetics and experiments with fruit fly genes has helped revolutionize or knowledge of the connections between DNA and behavior both animal and human.