Small Angle X-Ray and Neutron Scattering from Solutions of Biological Macromolecules

Small Angle X-Ray and Neutron Scattering from Solutions of Biological Macromolecules PDF

Author: Dmitri I. Svergun

Publisher: Oxford University Press, USA

Published: 2020-01-06

Total Pages: 368

ISBN-13: 9780198854210

DOWNLOAD EBOOK →

This book describes all aspects of the technique of small-angle scattering of X-rays and neutrons, including instrumentation, sample requirements, data interpretation and modelling methods, in a comprehensive way and gives examples of applications in various fields of biophysics and biochemistry.

Small Angle X-Ray and Neutron Scattering from Solutions of Biological Macromolecules

Small Angle X-Ray and Neutron Scattering from Solutions of Biological Macromolecules PDF

Author: Dmitri I. Svergun

Publisher: Oxford University Press

Published: 2013-08-08

Total Pages: 369

ISBN-13: 0199639531

DOWNLOAD EBOOK →

This book describes all aspects of the technique of small-angle scattering of X-rays and neutrons, including instrumentation, sample requirements, data interpretation and modelling methods, in a comprehensive way and gives examples of applications in various fields of biophysics and biochemistry.

Handbook of Food Structure Development

Handbook of Food Structure Development PDF

Author: Fotis Spyropoulos

Publisher: Royal Society of Chemistry

Published: 2019-10-31

Total Pages: 516

ISBN-13: 178801216X

DOWNLOAD EBOOK →

The most useful properties of food, i.e. the ones that are detected through look, touch and taste, are a manifestation of the food’s structure. Studies about how this structure develops or can be manipulated during food production and processing are a vital part of research in food science. This book provides the status of research on food structure and how it develops through the interplay between processing routes and formulation elements. It covers food structure development across a range of food settings and consider how this alters in order to design food with specific functionalities and performance. Food structure has to be considered across a range of length scales and the book includes a section focusing on analytical and theoretical approaches that can be taken to analyse/characterise food structure from the nano- to the macro-scale. The book concludes by outlining the main challenges arising within the field and the opportunities that these create in terms of establishing or growing future research activities. Edited and written by world class contributors, this book brings the literature up-to-date by detailing how the technology and applications have moved on over the past 10 years. It serves as a reference for researchers in food science and chemistry, food processing and food texture and structure.

Structure Analysis by Small-Angle X-Ray and Neutron Scattering

Structure Analysis by Small-Angle X-Ray and Neutron Scattering PDF

Author: L.A. Feigin

Publisher: Springer Science & Business Media

Published: 2013-11-11

Total Pages: 339

ISBN-13: 1475766246

DOWNLOAD EBOOK →

Small-angle scattering of X rays and neutrons is a widely used diffraction method for studying the structure of matter. This method of elastic scattering is used in various branches of science and technology, includ ing condensed matter physics, molecular biology and biophysics, polymer science, and metallurgy. Many small-angle scattering studies are of value for pure science and practical applications. It is well known that the most general and informative method for investigating the spatial structure of matter is based on wave-diffraction phenomena. In diffraction experiments a primary beam of radiation influences a studied object, and the scattering pattern is analyzed. In principle, this analysis allows one to obtain information on the structure of a substance with a spatial resolution determined by the wavelength of the radiation. Diffraction methods are used for studying matter on all scales, from elementary particles to macro-objects. The use of X rays, neutrons, and electron beams, with wavelengths of about 1 A, permits the study of the condensed state of matter, solids and liquids, down to atomic resolution. Determination of the atomic structure of crystals, i.e., the arrangement of atoms in a unit cell, is an important example of this line of investigation.

Soft-Matter Characterization

Soft-Matter Characterization PDF

Author: Redouane Borsali

Publisher: Springer Science & Business Media

Published: 2008-07-28

Total Pages: 1490

ISBN-13: 140204464X

DOWNLOAD EBOOK →

This 2-volume set includes extensive discussions of scattering techniques (light, neutron and X-ray) and related fluctuation and grating techniques that are at the forefront of this field. Most of the scattering techniques are Fourier space techniques. Recent advances have seen the development of powerful direct imaging methods such as atomic force microscopy and scanning probe microscopy. In addition, techniques that can be used to manipulate soft matter on the nanometer scale are also in rapid development. These include the scanning probe microscopy technique mentioned above as well as optical and magnetic tweezers.

Biological Small Angle Scattering: Techniques, Strategies and Tips

Biological Small Angle Scattering: Techniques, Strategies and Tips PDF

Author: Barnali Chaudhuri

Publisher: Springer

Published: 2017-12-07

Total Pages: 268

ISBN-13: 981106038X

DOWNLOAD EBOOK →

This book provides a clear, comprehensible and up-to-date description of how Small Angle Scattering (SAS) can help structural biology researchers. SAS is an efficient technique that offers structural information on how biological macromolecules behave in solution. SAS provides distinct and complementary data for integrative structural biology approaches in combination with other widely used probes, such as X-ray crystallography, Nuclear magnetic resonance, Mass spectrometry and Cryo-electron Microscopy. The development of brilliant synchrotron small-angle X-ray scattering (SAXS) beam lines has increased the number of researchers interested in solution scattering. SAS is especially useful for studying conformational changes in proteins, highly flexible proteins, and intrinsically disordered proteins. Small-angle neutron scattering (SANS) with neutron contrast variation is ideally suited for studying multi-component assemblies as well as membrane proteins that are stabilized in surfactant micelles or vesicles. SAS is also used for studying dynamic processes of protein fibrillation in amyloid diseases, and pharmaceutical drug delivery. The combination with size-exclusion chromatography further increases the range of SAS applications. The book is written by leading experts in solution SAS methodologies. The principles and theoretical background of various SAS techniques are included, along with practical aspects that range from sample preparation to data presentation for publication. Topics covered include techniques for improving data quality and analysis, as well as different scientific applications of SAS. With abundant illustrations and practical tips, we hope the clear explanations of the principles and the reviews on the latest progresses will serve as a guide through all aspects of biological solution SAS. The scope of this book is particularly relevant for structural biology researchers who are new to SAS. Advanced users of the technique will find it helpful for exploring the diversity of solution SAS methods and applications. Chapter 3 of this book is available open access under a CC BY 4.0 license at link.springer.com.

Synchrotron Light Sources and Free-Electron Lasers

Synchrotron Light Sources and Free-Electron Lasers PDF

Author: Eberhard J. Jaeschke

Publisher: Springer

Published: 2016-05-27

Total Pages: 0

ISBN-13: 9783319143934

DOWNLOAD EBOOK →

Hardly any other discovery of the nineteenth century did have such an impact on science and technology as Wilhelm Conrad Röntgen’s seminal find of the X-rays. X-ray tubes soon made their way as excellent instruments for numerous applications in medicine, biology, materials science and testing, chemistry and public security. Developing new radiation sources with higher brilliance and much extended spectral range resulted in stunning developments like the electron synchrotron and electron storage ring and the freeelectron laser. This handbook highlights these developments in fifty chapters. The reader is given not only an inside view of exciting science areas but also of design concepts for the most advanced light sources. The theory of synchrotron radiation and of the freeelectron laser, design examples and the technology basis are presented. The handbook presents advanced concepts like seeding and harmonic generation, the booming field of Terahertz radiation sources and upcoming brilliant light sources driven by laser-plasma accelerators. The applications of the most advanced light sources and the advent of nanobeams and fully coherent x-rays allow experiments from which scientists in the past could not even dream. Examples are the diffraction with nanometer resolution, imaging with a full 3D reconstruction of the object from a diffraction pattern, measuring the disorder in liquids with high spatial and temporal resolution. The 20th century was dedicated to the development and improvement of synchrotron light sources with an ever ongoing increase of brilliance. With ultrahigh brilliance sources, the 21st century will be the century of x-ray lasers and their applications. Thus, we are already close to the dream of condensed matter and biophysics: imaging single (macro)molecules and measuring their dynamics on the femtosecond timescale to produce movies with atomic resolution.

Temperature-Responsive Polymers

Temperature-Responsive Polymers PDF

Author: Vitaliy V. Khutoryanskiy

Publisher: John Wiley & Sons

Published: 2018-06-01

Total Pages: 408

ISBN-13: 1119157803

DOWNLOAD EBOOK →

An authoritative resource that offers an understanding of the chemistry, properties and applications of temperature-responsive polymers With contributions from a distinguished panel of experts, Temperature-Responsive Polymers puts the focus on hydrophilic polymers capable of changing their physicochemical properties in response to changes in environmental temperature. The contributors review the chemistry of these systems, and discuss a variety of synthetic approaches for preparation of temperature-responsive polymers, physicochemical methods of their characterisation and potential applications in biomedical areas. The text reviews a wide-variety of topics including: The characterisation of temperature-responsive polymers; Infrared and Raman spectroscopy; Applications of temperature-responsive polymers grafted onto solid core nanoparticles; and much more. The contributors also explore how temperature-responsive polymers can be used in the biomedical field for applications such as tissue engineering. This important resource: Offers an important synthesis of the current research on temperature-responsive polymers Covers the chemistry, the synthetic approaches for presentation and the physiochemical method of temperature-responsive polymers Includes a review of the fundamental characteristics of temperature-responsive polymers Explores many of the potential applications in biomedical science, including drug delivery and gene therapy Written for polymer scientists in both academia and industry as well as postgraduate students working in the area of stimuli-responsive materials, this vital text offers an exploration of the chemistry, properties and current applications of temperature-responsive polymers.

Characterization of Polymer Blends

Characterization of Polymer Blends PDF

Author: Sabu Thomas

Publisher: John Wiley & Sons

Published: 2015-02-09

Total Pages: 972

ISBN-13: 3527331530

DOWNLOAD EBOOK →

Filling the gap for a reference dedicated to the characterization of polymer blends and their micro and nano morphologies, this book provides comprehensive, systematic coverage in a one-stop, two-volume resource for all those working in the field. Leading researchers from industry and academia, as well as from government and private research institutions around the world summarize recent technical advances in chapters devoted to their individual contributions. In so doing, they examine a wide range of modern characterization techniques, from microscopy and spectroscopy to diffraction, thermal analysis, rheology, mechanical measurements and chromatography. These methods are compared with each other to assist in determining the best solution for both fundamental and applied problems, paying attention to the characterization of nanoscale miscibility and interfaces, both in blends involving copolymers and in immiscible blends. The thermodynamics, miscibility, phase separation, morphology and interfaces in polymer blends are also discussed in light of new insights involving the nanoscopic scale. Finally, the authors detail the processing-morphology-property relationships of polymer blends, as well as the influence of processing on the generation of micro and nano morphologies, and the dependence of these morphologies on the properties of blends. Hot topics such as compatibilization through nanoparticles, miscibility of new biopolymers and nanoscale investigations of interfaces in blends are also addressed. With its application-oriented approach, handpicked selection of topics and expert contributors, this is an outstanding survey for anyone involved in the field of polymer blends for advanced technologies.