Sleep-Wake Neurobiology and Pharmacology

Sleep-Wake Neurobiology and Pharmacology PDF

Author: Hans-Peter Landolt

Publisher: Springer Nature

Published: 2019-09-03

Total Pages: 481

ISBN-13: 3030112721

DOWNLOAD EBOOK →

This volume connects current ideas and concepts about sleep functions and circadian rhythms with the search for novel target-selective sleep-wake therapeutics. To do so, it provides a timely, state-of-the-art overview of sleep-wake mechanisms in health and disease, ongoing developments in drug discovery, and their prospects for the clinical treatment of sleep-disordered patients. It particularly focuses on the concept that sleep and wakefulness mutually affect each other, and the future therapeutic interventions with either sleep- or wake-promoting agents that are expected to not only improve the quality of sleep but also the waking behavior, cognition, mood and other sleep-associated physiological functions. The chapter 'Sleep Physiology, Circadian Rhythms, Waking Performance and the Development of Sleep-Wake Therapeutics' available open access under a CC BY 4.0 license at link.springer.com

The Pharmacology of Sleep

The Pharmacology of Sleep PDF

Author: Anthony Kales

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 603

ISBN-13: 3642578365

DOWNLOAD EBOOK →

A review of the current state of the clinical and basic science of the pharmacology of sleep. The information provided ranges from a historical perspective to current concepts of sleep mechanisms, including the interaction between pharmacology and sleep-wake regulation and between chronopahrmacology and sleep-wake rhythms. For the first time in one single volume, both the basic mechanisms of sleep, and the basic and clinical aspects of the pharmacology of sleep are dealt with in a thorough, comprehensive and authoritative manner. The chapters, written by the foremost scientific authorities in this field, integrate the latest information on the basic mechanisms of drugs as they relate to their effects on sleep.

The Pharmacology of Sleep

The Pharmacology of Sleep PDF

Author: Anthony Kales

Publisher: Springer

Published: 2011-09-27

Total Pages: 583

ISBN-13: 9783642578373

DOWNLOAD EBOOK →

A review of the current state of the clinical and basic science of the pharmacology of sleep. The information provided ranges from a historical perspective to current concepts of sleep mechanisms, including the interaction between pharmacology and sleep-wake regulation and between chronopahrmacology and sleep-wake rhythms. For the first time in one single volume, both the basic mechanisms of sleep, and the basic and clinical aspects of the pharmacology of sleep are dealt with in a thorough, comprehensive and authoritative manner. The chapters, written by the foremost scientific authorities in this field, integrate the latest information on the basic mechanisms of drugs as they relate to their effects on sleep.

Sleep and Sleep Disorders:

Sleep and Sleep Disorders: PDF

Author: Malcolm Lader

Publisher: Springer Science & Business Media

Published: 2009-11-06

Total Pages: 319

ISBN-13: 0387276823

DOWNLOAD EBOOK →

Many recent discoveries in both laboratory and clinical settings have greatly increased our understanding of sleep medicine and the relevant psychopharmacology. This timely book serves to present updated information about the neuropsychopharmacology of sleep as this field enters mainstream psychiatry, neurology and medicine This volume has assembled articles that summarize and review carefully, a chosen selection of the latest discoveries concerning sleep medicine, sleep physiology and sleep pharmacology. Outstanding contributions have been sought from acknowledged experts in their respective fields. The goal of the volume is to present the more recent developments and advances in the fields of sleep and neuropsychopharmacology, as well as to provide a context for considering them both in depth and from multidisciplinary perspectives. This volume brings together the collective expertise of clinicians and basic researchers who represent a range of interests in neuroscience, neuropharmacology, sleep physiology, and biological rhythms. Presenting a thoughtful balance of basic experimental and clinical facts and viewpoints, this book will serve as a foundation for understanding, and ultimately treating, sleep disorders.

The Gating and Maintenance of sleep and Wake: New Circuits and Insights

The Gating and Maintenance of sleep and Wake: New Circuits and Insights PDF

Author: Michael Lazarus

Publisher: Frontiers Media SA

Published: 2020-10-09

Total Pages: 299

ISBN-13: 2889660613

DOWNLOAD EBOOK →

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Neurochemistry of Sleep and Wakefulness

Neurochemistry of Sleep and Wakefulness PDF

Author: Jaime M. Monti

Publisher:

Published: 2008

Total Pages: 482

ISBN-13: 9780511374593

DOWNLOAD EBOOK →

Pharmacological approaches to our understanding of sleep have been at the forefront of sleep research for many years. Traditional techniques have included the use of pharmacological agonists and antagonists, as well as transmitter-specific lesions. These have been enhanced by the introduction of molecular genetics and the use of transgenes and targeted gene deletion. Neurochemistry of Sleep and Wakefulness is an exceptional, single source of information on the role of the major mammalian neurotransmitter systems involved in the regulation of sleep and waking. With contributions from internationally recognized experts, this book clearly describes how researchers have made use of the myriad techniques in their armamentarium to characterize the role of a given neurotransmitter in the regulation of sleep and waking. Suitable for experimental and clinical pharmacologists, the book will have wider appeal to sleep researchers, psychiatrists and any professional interested in the interdisciplinary areas of neurobiology and pharmacology.

Neurochemistry of Sleep and Wakefulness

Neurochemistry of Sleep and Wakefulness PDF

Author: Jaime Monti

Publisher: Cambridge University Press

Published: 2008-01-17

Total Pages: 456

ISBN-13: 1139467891

DOWNLOAD EBOOK →

Pharmacological approaches to our understanding of sleep have been at the forefront of sleep research for many years. Traditional techniques have included the use of pharmacological agonists and antagonists, as well as transmitter-specific lesions. These have been enhanced by the introduction of molecular genetics and the use of transgenes and targeted gene deletion. Neurochemistry of Sleep and Wakefulness is an exceptional, single source of information on the role of the major mammalian neurotransmitter systems involved in the regulation of sleep and waking. With contributions from internationally recognized experts, this book clearly describes how researchers have made use of the myriad techniques in their armamentarium to characterize the role of a given neurotransmitter in the regulation of sleep and waking. Suitable for experimental and clinical pharmacologists, the book will have wider appeal to sleep researchers, psychiatrists and any professional interested in the interdisciplinary areas of neurobiology and pharmacology.

The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle

The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle PDF

Author: Eric Murillo-Rodriguez

Publisher: Academic Press

Published: 2019-03-26

Total Pages: 220

ISBN-13: 0128167424

DOWNLOAD EBOOK →

The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle provides the first comprehensive overview on the molecular methodologies used to evaluate sleep while also examining the cellular, biochemical, genetic, and therapeutic aspects of the sleep-wake cycle. There have been profound changes in the landscape of approaches to the study of sleep – mainly in the areas of molecular biology and molecular techniques. With this great focus on using multidisciplinary molecular methods, chapters address significant advances in the molecular mechanisms underlying sleep and the techniques researchers use to study this phenomenon. Written by world-leading experts in the area, this book is of great interest to researchers working in the sleep field and to anyone interested in one of the most mysterious phenomena in science – why we sleep and why we cannot survive without it. Reviews the neurobiological and cellular mechanisms of the sleep-wake cycle Provides the implications of sleep in health and disease Contrasts different techniques to study molecular mechanisms Contains case studies to better illustrate points Covers sleep disturbance and health problems involved in sleep Includes chapters on the ontogeny of sleep, along with multiple mechanisms for sleep generation

Serotonin and Sleep: Molecular, Functional and Clinical Aspects

Serotonin and Sleep: Molecular, Functional and Clinical Aspects PDF

Author: Jaime M. Monti

Publisher: Springer Science & Business Media

Published: 2008-03-04

Total Pages: 627

ISBN-13: 3764385618

DOWNLOAD EBOOK →

This book focuses on the neuropsychopharmacology of serotonin and its role in sleep and wakefulness, presenting neurochemical, electrophysiological, and neuropharmacological approaches to understand the mechanisms of serotonin and related substances. Covering core and contemporary topics in the area, this volume is valuable for all researchers interested in interdisciplinary studies concerning drugs affecting the central nervous system.

Dopamine and Sleep

Dopamine and Sleep PDF

Author: Jaime M. Monti

Publisher: Springer

Published: 2016-10-24

Total Pages: 286

ISBN-13: 331946437X

DOWNLOAD EBOOK →

This book offers a comprehensive but highly readable compilation of papers on the role of dopamine in sleep and sleep disorders. Leading experts in sleep medicine, psychiatry and neuroendocrinology provide a broad perspective on the field, from established theories to the latest research advances. Accordingly, it represents an interdisciplinary, cutting-edge guide for sleep disorder specialists, sleep researchers, psychiatrists, neurologists, pulmonologists, psychologists, and behavioral sleep medicine specialists.