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Skin Immune System (SIS)

Author: Jan D. Bos

Publisher: CRC Press

Published: 1997-04-10

Total Pages: 768

ISBN-13: 9780849340161

Immunodermatology is a field covering the majority of skin diseases, including the most prevalent onesin the general population. The Second Edition of Skin Immune System (SIS) discusses immune-mediated skin diseases and disease groups in which the SIS plays a role. It covers major findings in immunophysiology and immunopathology that have occurred since the introduction of the First Edition in 1990. As the subtitle indicates, the Second Edition adds a new emphasis on cutaneous immunology, and also includes new information on immune-based therapeutic interventions and methods, such as phototherapy and the immunological therapy of skin cancer. The book contains Part I, with introductory chapters; Part II, with descriptions of the cellular elements; and Part III, which describes the humoral and molecular components of SIS. Part IV follows to integrate the facts described in Parts II and III into concepts of pathophysiology. It contains a number of concepts entitled "response patterns" that describe how the constitutional elements of SIS work together. New in this edition are the descriptions of immunodermatological diseases individually described in Part V. Part VI is also all new and summarizes principles of immunotherapy.

Skin Immune System (SIS)

Author: Jan D. Bos

Publisher: CRC Press

Published: 1990-03-26

Total Pages: 520

ISBN-13: 9780849349454

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The aim of this comprehensive volume is to provide detailed and well-referenced information pertaining to the immunology of skin, particularly that of man. It includes a short description of comparative immunology plus an introduction into the skin immune system and skin associated lymphoid tissues. This section also describes adhesion molecules and their role in cell migration pathways. This interesting text provides up-to-date knowledge of keratinocytes, lymphocytes, Langerhans cells, monocytes, endothelial cells and mast cells. It describes the humoral constituents of the human integument's defense system, as well as the major response patterns of the skin immune system. This easy-to-read reference outlines future developments which are to be expected in the field of immunodermatology and the immunobiology of the integument. Those involved with immunology, biology, and dermatology will find this book interesting, informative, and indispensable.

Skin Immune System

Author: Jan D. Bos

Publisher: Informa Healthcare

Published: 2005

Total Pages: 824

ISBN-13: 9780849319594

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Top scientific authors contribute their expertise and put a wealth of complex information into perspective in Skin Immune System: Cutaneous Immunology & Clinical Immunodermatology, Third Edition. This edition provides an overview of the skin immune system (SIS), a totally updated section on immunodermatological diseases, and six new chapters. Part I presents historical and comparative information on immunodermatology and includes a new chapter on the immunogenetics of inflammatory skin disease, while Part II covers the cellular elements of SIS and highlights newly defined functional subclasses of cells. Part III describes the humoral elements of SIS and provides two new chapters which focus on defensins and cathelicidins, and on the chemokines of human skin. Part IV discusses how the cellular and humoral elements of SIS interact under different circumstances and includes a new chapter on signal transduction pathways in cutaneous immunology. Part V focuses on dermatological diseases with a significant immunological background with a new chapter on the immunology of cutaneous drug eruptions, followed by Part VI on immunotherapy in dermatology, which features a new chapter reflecting the recent wave of products from biotechnology. Since the publication of the previous editions, a great deal of significant information has become available in almost all areas of cutaneous immunology and clinical immunodermatology. This progress has now been reflected in a completely updated and expanded resource.

The Skin Immune Response to Infectious Agents

Author: Fatima Conceição-Silva

Publisher: Frontiers Media SA

Published: 2021-10-14

Total Pages: 223

ISBN-13: 2889714926

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Dermatologic Immunity

Author: Brian J. Nickoloff

Publisher: Karger Medical and Scientific Publishers

Published: 2008-01-01

Total Pages: 391

ISBN-13: 3805583915

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Nickeloff (skin cancer research, Cardinal Bernardin Cancer Center, Chicago) and Nestle (cutaneous medicine and immunotherapy, King's College, London School of Medicine at Guy's, UK) assemble 19 review articles on autoimmune disease processes that affect the skin, covering both humoral and cellular immunity. The etiology, cellular and molecular mechanisms, therapeutic strategies, and pathophysiology of diseases such as psoriasis, dermatitis, cutaneous lupus erythematosus, vitiligo, and scleroderma are discussed by individuals in dermatology, genetics, immunology, and pathology who are based around the world. The book is aimed at clinical researchers, students, allergists, immunologists, dermatologists, and internists.

Skin Immune System (SIS)

Author:

Publisher:

Published: 2005

Total Pages: 0

ISBN-13: 9780367801786

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Immunology of the Skin

Author: Kenji Kabashima

Publisher: Springer

Published: 2018-04-25

Total Pages: 0

ISBN-13: 9784431567127

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This book reviews the role of each cell subset in the skin, providing the basics for understanding skin immunology and the mechanisms of skin diseases. The skin is one of the immune organs and is continually exposed to foreign antigens and external stimuli that must be monitored and characterized for possible elimination. Upon exposure to foreign antigens, the skin can elicit a variety of immune responses in harmony with skin components that include keratinocytes, dendritic cell subsets, mast cells, basophils, fibroblasts, macrophages, gamma-delta T cells, neutrophils, myeloid-derived suppressor cells, vascular and lymphatic cells, hair follicles, platelets, and adipose tissues, among others. In the past 10 years, knowledge of immunology has expanded drastically in areas such as innate immunity (Toll-like receptors, C-type lectins), and host defenses to bacteria and viruses, and this increased knowledge has led to the development of more effective treatment of psoriasis and other skin diseases. This book provides updates on the mechanisms of skin diseases including contact dermatitis, atopic dermatitis, psoriasis, urticaria, drug eruption, bullous diseases, anaphylaxis, graft-versus-host disease, rosacea, lymphoma, photodermatology, and collagen vascular diseases. Understanding the basics of skin immunology will help clinicians and dermatologists use new therapeutics such as biologics efficiently. Serving as an intermediary between basic science and clinical medicine, this book gives readers the opportunity to understand and marvel at the mystery and fascination of skin immunology.

Epidermal Langerhans Cells

Author: Gerold Schuler

Publisher: CRC Press

Published: 1990-12-26

Total Pages: 336

ISBN-13: 9780849356469

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Epidermal Langerhans Cells focuses on epidermal Langerhans cells (LCs) and the important role they play in the induction of contact hypersensitivity and graft rejection. This in-depth work discusses how these antigen-presenting cells are modulated by various physicochemical agents (such as UV light) and how they can be infected by the AIDS virus. It also reveals that cytokines mediate their development into potent T cell-stimulatory dendritic cells. This comprehensive review covers important experimental details and methods, and fascinating information on LCs. It also provides an overview of the immune system as it relates to the skin in health and disease. This up-to-date publication is an indispensable resource for all investigative and clinical dermatologists, as well as immunologists interested in antigen-presenting cells.

Clinical and Basic Immunodermatology

Author: Anthony Gaspari

Publisher: Springer Science & Business Media

Published: 2008-11-05

Total Pages: 812

ISBN-13: 1848001657

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Dermatologists are being asked to understand the pathophysiology of a number of immune-mediated skin diseases. In addition, a number of new products have appeared on the market during the past decade which requires an understanding of the mechanisms of action of these drugs. Dermatologists, however, have no easily understood book to which they can refer to regarding the disease or the drug.

Immunology and Drug Therapy of Allergic Skin Diseases

Author: Carla A.F.M. Bruijnzeel-Koomen

Publisher: Springer

Published: 2012-12-06

Total Pages: 224

ISBN-13: 3034884648

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Allergic skin diseases belong to the most common dermatoses. This book deals with fundamental (in particular immunological aspects) as well as clinical symptoms and therapeutic strategies of the allergic skin diseases. Cells involved in the pathomechanisms of allergic skin disease are described in individual chapters. The allergic skin diseases which will be discussed are atopic dermatitis, being the chronic inflammatory skin disease with the highest prevalence, allergic contact dermatitis with special focus on contact dermatitis from cosmetics, being the most frequent cause of contact dermatitis and occupational contact dermatitis. The broad ethiology of urticaria and the value of several therapeutic strategies will be explained. The chapter on drug allergy will deal with the variety of symptoms and the difficulties concerning in vitro and in vivo diagnosis. The book is of great interest to clinicians working in the field of dermatology, allergology, pediatrics and even general practitioners...