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Author: Peter M. Elias
Publisher: CRC Press
Published: 2005-09-22
Total Pages: 634
ISBN-13: 084936129X
DOWNLOAD EBOOK →A must-have reference for any researcher or scientist interested in cutaneous protective mechanisms, this guide provides expertly researched chapters on every aspect of stratum corneum structure, function, and development, as well as detailed sections on barrier-repair strategies and the role of barrier function in diseases such as atopic dermatiti
Author: T. Agner
Publisher: Karger Medical and Scientific Publishers
Published: 2016-02-04
Total Pages: 164
ISBN-13: 3318055867
DOWNLOAD EBOOK →Although a very fragile structure, the skin barrier is probably one of the most important organs of the body. Inward/out it is responsible for body integrity and outward/in for keeping microbes, chemicals, and allergens from penetrating the skin. Since the role of barrier integrity in atopic dermatitis and the relationship to filaggrin mutations was discovered a decade ago, research focus has been on the skin barrier, and numerous new publications have become available. This book is an interdisciplinary update offering a wide range of information on the subject. It covers new basic research on skin markers, including results on filaggrin and on methods for the assessment of the barrier function. Biological variation and aspects of skin barrier function restoration are discussed as well. Further sections are dedicated to clinical implications of skin barrier integrity, factors influencing the penetration of the skin, influence of wet work, and guidance for prevention and saving the barrier. Distinguished researchers have contributed to this book, providing a comprehensive and thorough overview of the skin barrier function. Researchers in the field, dermatologists, occupational physicians, and related industry will find this publication an essential source of information.
Author: Hans Schaefer
Publisher: S. Karger AG (Switzerland)
Published: 1996
Total Pages: 336
ISBN-13:
DOWNLOAD EBOOK →Skin Barrier is the first book to be written exclusively by researchers for researchers as a convenient desktop reference. It focuses on several key aspects of the skin barrier including composition and structure and a description of the properties governing the diffusion of compounds across the skin. Although there has been a large number of laboratories involved in measuring percutaneous absorption over the past 15 to 20 years, it is only recently that there has been a general consensus in the scientific community regarding the development of standard protocols. Recognizing the importance of this, the authors have included two chapters detailing the protocol used in measuring and predicting percutaneous absorption and a discussion on the practical application of these techniques to solve associated problems. In order to provide the researcher and especially the student with access to more detailed information, the book features a comprehensive listing of references published over the past 10 years. Skin Barrier is the only desktop reference for dermatologists, cosmetologists, biochemists, biologists, and those in the pharmaceutics industry, who need detailed and accurate information about the skin barrier on a daily basis. No R & D department should be without a copy.
Author: R.M. Marks
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 213
ISBN-13: 9400912919
DOWNLOAD EBOOK →Author: Georg T. Wondrak
Publisher: Springer
Published: 2016-08-22
Total Pages: 457
ISBN-13: 3319431579
DOWNLOAD EBOOK →It is now established that the interplay between environmental exposure and molecular stress response pathways plays a critical role in skin health and disease, and a refined mechanistic understanding of this phenomenon at the molecular level promises to open new avenues for targeted therapeutic strategies that may benefit patients in the near future. Coauthored by recognized international leaders in molecular and clinical biomedical sciences, this novel book provides a comprehensive perspective on environmental exposure-induced skin stress response pathways. Focusing on molecular opportunities targeting skin stress response pathways that are involved in cutaneous barrier function and repair, antimicrobial defense, immune regulation, inflammation, and malignant progression, the book is essential reading for students, basic researchers, and biomedical health care professionals interested in skin health and disease with implications for small molecule therapeutic development.
Author: J. Comstock
Publisher: Karger Medical and Scientific Publishers
Published: 2021-01-19
Total Pages: 178
ISBN-13: 3318066907
DOWNLOAD EBOOK →Cosmeceuticals are ingredients or products that provide cosmetic and therapeutic benefits and which can be obtained without a prescription. They are one of the fastest growing segments in the personal care product market. Even in the worst economic climate, sales of cosmetics remain robust. Beauty enhancers are our best means of feel-good escapism, and we are not about to give them up. The ingredients, sales locations, and the regulation of sales are dynamic aspects of the industry. Here we give you a heads-up on where the market is going so you can make strategic decisions for your practice. This book will give you an understanding of facial cosmeceuticals examining the needs of the face, moisturizer formulation, noninvasive testing, and clinical evaluation to establish efficacy. It sheds light on topics such as the delivery mechanisms of active ingredients, vitamin A and C and other antioxidants, growth factors and stem cells, peptides, or amino acids. Topics also include the use of cosmeceuticals for the treatment of acne, rosacea, and hair loss and for hair care as well as the treatment of scars and cosmeceuticals for sun protection and protection from pollution. It also covers aspects of nutraceuticals and diets for healthy skin.
Author: Peter J. Frosch
Publisher: Springer Science & Business Media
Published: 2006-06-07
Total Pages: 1127
ISBN-13: 354031301X
DOWNLOAD EBOOK →It is an unusual event for a textbook covering such a national and international networks and the use of highly specialized field as contact dermatitis to be standardized methodology, a highly differentiated published in its fourth edition within a time period picture can now be painted; we know the major p- of 13 years. When the European and Environmental fessions at risk, as well as the influences of age and Contact Dermatitis Research Group was founded in various cofactors. This is a solid basis for preventive 1985,one of the major goals was to edit a textbook of measures. A new allergen, described in one center, high scientific standard written by renown experts can now be tested on a large scale in a short time and keep it regularly updated. The greatest danger period. If the data evaluation shows an unacceptably for a textbook is to become outdated – then it stays high rate of sensitization in the exposed population, on the bookshelf and is rarely consulted. The contin- regulatory measures will be undertaken to protect uous flow of new medicaments, the fascinating the consumer. A recent example is the “methyldib- improvements in diagnostic image analysis and ever- mo glutaronitrile story. ” changing operative procedures are the reasons for These and other issues of importance are covered considerable knowledge deficits in old textbooks, in depth in the newest edition of this textbook.
Author: C. Surber
Publisher: Karger Medical and Scientific Publishers
Published: 2018-08-21
Total Pages: 214
ISBN-13: 3318063851
DOWNLOAD EBOOK →The concept of expressing acidity as the negative logarithm of the hydrogen ion concentration was defined and termed pH in the beginning of the 20th century. The general usefulness of the pH concept for life science was recognized and later gained importance to analytical research. Reports on results of pH measurements from living skin established the term acid mantle - the skin's own protective shield that maintains a naturally acid pH. It is invisible to the eye but crucial to the overall wellbeing of skin. Chronic alkalization can throw this acid mantle out of balance, leading to inflammation, dermatitis, and atopic skin diseases. It is therefore no surprise, that skin pH shifts have been observed in various skin pathologies. It is also obvious that the pH in topically applied preparations may play an important role. Optimal pH and buffer capacity within topical preparations not only support stability of active ingredients and auxiliary materials, but may also increase absorption of the non-ionized species of an acidic or a basic active ingredient. They may even open up opportunities to modify and "correct" skin pH and hence accelerate barrier recovery and maintain or enhance barrier integrity. Further efforts are needed to standardize and improve pH measurements in biological media or pharmaceutical/cosmetic vehicles to increase and ensure quality, comparability, and relevance of research data. In this volume, we present a unique collection of papers that address past, present and future issues of the pH of healthy and diseased skin. It is hoped that this collection will foster future efforts in clinical and experimental skin research.
Author: Janice C. Colwell
Publisher: Elsevier Health Sciences
Published: 2004-05-06
Total Pages: 566
ISBN-13: 9780323022484
DOWNLOAD EBOOK →Dedicated to ostomies and continent diversions, this comprehensive reference book features information on the history of enterostomal therapy, anatomy and physiology of diseases that necessitate intestinal or urinary diversions, pouching system management principles, ostomy related complications, care of the cancer patient as well as the patient with chronic disease, and current trends and issues affecting the person with an ostomy. Current topics covered include intestinal diversions requiring temporary diversions, medical and surgical treatments for inflammatory bowel disease, colo-rectal cancers advances and ischemic intestinal disease. Fecal and Urinary Diversions: Management Principles is a valuable resource to students, nurses, physicians, surgeons, and individuals who care for a person with an ostomy without the benefit of a Certified Ostomy (ET) Nurse. Covers lifespan considerations to address the special needs of patients of all ages. Includes an 8-page color insert with 25 full-color photos illustrating ostomy-related complications to help nurses improve their assessment skills. Offers a unique framework for pouch selection to help nurses choose the most effective and cost-conscious options. Covers coping and quality-of-life issues to guide nurses in handling these important patient and professional considerations. Features practical, step-by-step guidelines for pouching, irrigation, and other techniques. Provides review questions and answers to help evaluate learning and prepare for certification or recertification.
Author: Johann W. Wiechers
Publisher: Allured Publishing Corporation
Published: 2008
Total Pages: 0
ISBN-13: 9781932633443
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