Schistosomiasis

Schistosomiasis PDF

Author: W. Evan Secor

Publisher: Springer Science & Business Media

Published: 2006-02-10

Total Pages: 242

ISBN-13: 0387233628

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Human schistosomiasis is a disease with a rich and well-documented past, and every expectation of an unfortunately long future. These infections were known to the ancient Egyptians and their transmission shows little evidence of slowing down, globally. The good news is that field applicable, and increasingly affordable, chemotherapy has been available for almost 25 years. Using chemotherapy and other means of control, some countries have decreased transmission and made excellent headway against morbidity. The bad news is that the public health problems caused by schistosomiasis are still with us, with the estimated number of cases of schistosomiasis, while shifting geographically, remaining approximately 200 million for the last 30 years. In fact, with the development of field usable ultrasound technology and meta-analyses performed on existing data, there is a new appreciation for the extent of non-lethal morbidity associated with these infections. While the percentage of individuals with severe hepatosplenic disease remains below 10%, recent reassessments of morbidity associated with schistosomiasis indicate that the prevelance of symptoms and the cost in diability-adjusted life years is much greater than was previously, commonly appreciated (Van der Werf, M. J. , et al. 2003, Acta Tropica 86:125-139; Charles H. King, personnel communication). Strong impetus for addressing these issues is provided by the World Health Assembly’s recently passed Resolution 54. 19, which calls for efforts to reduce morbidity caused by schistosomiasis and soil-transmitted helminths in school-aged children, largely through chemotherapy campaigns.

Infection and Autoimmunity

Infection and Autoimmunity PDF

Author: Yehuda Shoenfeld

Publisher: Elsevier

Published: 2015-01-27

Total Pages: 1071

ISBN-13: 0444632727

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Autoimmune diseases are conditions where the immune system attacks the body organs instead of foreign invaders. This book deals with the various mechanisms by which infectious agents can trigger autoimmunity such as molecular mimicry and polyclonal activation. An overview is given with regard to bacteria, viruses, and parasites associated with autoimmunity, and a summary is given on classical autoimmune diseases and the infecting agents that can induce them. Includes completely updated and new chapters Brings the reader up to date and allows easy access to individual topics in one place Identifies infectious agents as pathogenic or protective in many autoimmune diseases

Parasitic and Related Diseases

Parasitic and Related Diseases PDF

Author: Thomas C. Cheng

Publisher: Springer Science & Business Media

Published: 2013-03-09

Total Pages: 172

ISBN-13: 1468450271

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The study of parasites and their interactions with hosts continues to represent a challenging area of modern biology. The availability of new techniques and instrumentation, coupled with the development of daring new hypotheses and concepts, has paved the way for the dramatic evolution of parasitology from a static descriptive endeavor to a dynamic one based on biochemistry, immunology, molecular biology, and modern cell biology. Studies of this nature obviously fall within the domain of pathobiology. Consequently, when the contributions included in this volume of Comparative PathobioZogy were offered to this series. after critical review, we welcomed the opportunity to make them available to the scientific community. The contributions included herein represent presentations delivered before enthusiastic audiences at three different symposia, all held in 1983. The first, entitled "Some Aspects of Modern Parasitology", was organized by Dr. Gary E. Rodrick of the University of South Florida and myself on behalf of the American Society of Zoologists. The chapters by C. E. Carter and B. M. Wickwire. B. J. Bogitsh, and W. M. Kemp were originally presented at that symposium. The second symposium. organized by Dr. G. Balouet of the Faculte de Medecine, Brest, France, and myself on behalf,of the Society for Invertebrate Pathology, was entitled "Cellular Reactions in Invertebrates." The chapters by G. Balouet and M. Poder and M. Brehelin were originally presented at this symposium.