Betel-quid and Areca-nut Chewing and Some Areca-nut-derived Nitrosamines

Betel-quid and Areca-nut Chewing and Some Areca-nut-derived Nitrosamines PDF

Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Publisher: IARC

Published: 2004

Total Pages: 354

ISBN-13: 9789283212850

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A working group of sixteen experts from seven countries re-evaluated the evidence of the carcinogenicity of betel-quid and areca-nut chewing and some areca-nut related nitrosamines. Betel-quid and areca-nut chewing are widely practised in many parts of Asia and in Asian-migrant communities elsewhere in the world. There are hundreds of millions of users worldwide. They evaluated betel quid with tobacco as carcinogenic to humans (Group 1) on the basis of sufficient evidence of an increased risk of cancer of the oral cavity, pharynx and oesophagus. The working group reviewed epidemiological studies of human cancer, mainly studies from India, Pakistan and Taiwan (China). Studies on betel quid with tobacco and areca nut with tobacco in experimental animals now also provide sufficient evidence of carcinogenicity. The working group also evaluated betel quid without tobacco as carcinogenic to humans (Group 1), on the basis of sufficient evidence of an increased risk of oral cancer. Studies on betel quid without tobacco and areca nut without tobacco in experimental animals now also provide sufficient evidence of carcinogenicity. Areca nut, a common ingredient of betel quid and many different chewing preparations, including those available commercially, has been observed to cause oral submucous fibrosis

Tobacco and Areca Nut

Tobacco and Areca Nut PDF

Author: V. M. Sivaramakrishnan

Publisher: Orient Blackswan

Published: 2001

Total Pages: 144

ISBN-13: 9788125020134

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This Book Traces The History Of The Tobacco Plant And The Various Ways In Which It Is Used. It Takes A Close Look At The Practices Of Smoking And Chewing Tobacco Leaves And The Harm It Can Cause And How It Contributes Significantly To The Prevalence Of Oral Cancer. The Book Is Particularly Relevant To India.

Smokeless Tobacco and Some Tobacco-specific N-nitrosamines

Smokeless Tobacco and Some Tobacco-specific N-nitrosamines PDF

Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Publisher: World Health Organization

Published: 2007

Total Pages: 642

ISBN-13: 9283212894

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This eighty-ninth volume of the IARC Monographs is the third and last of a series on tobacco-related agents. Volume 83 reported on the carcinogenicity of tobacco smoke and involuntary smoking (second-hand smoke or environmental tobacco smoke) (IARC 2004a). Volume 85 summarized the evidence on the carcinogenic risk of chewing betel quid with and without tobacco (IARC 2004b). That volume explored the variety of products chewed in South Asia and other parts of the word that contain areca nut in combination with other ingredients, often including tobacco. In this eighty-ninth volume, the carcinogenic risks associated with the use of smokeless tobacco, including chewing tobacco and snuff, are considered in a first monograph. The second monograph reviews some tobacco-specific nitrosamines. These agents were evaluated earlier in Volume 37 of the Monographs (IARC 1985) and information gathered since that time has been summarized and evaluated.

Smokeless Tobacco Control

Smokeless Tobacco Control PDF

Author: WHO Study Group on Smokeless Tobacco Control

Publisher:

Published: 1988

Total Pages: 92

ISBN-13:

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The study group concluded that: (1) the use of smokeless tobacco caused cancer in humans, the evidence for causality being strongest for cancers of the oral cavity; (2) there was some evidence that the habit also increased the risk of cancer of the nasal cavity, pharynx, larynx, oesophagus, pancreas, and urinary tract; and (3) laboratory studies clearly supported the observation that smokeless tobacco use caused a number of precancerous oral lesions and non-cancerous oral conditions, such as gingival recession. The group considered that, although the evidence relating smokeless tobacco use to other diseases was less conclusive, it might contribute to or support the pathogenesis of coronary artery and peripheral vascular diseases, hypertension, peptic ulcers, and fetal toxicity.

Textbook of Oral Cancer

Textbook of Oral Cancer PDF

Author: Saman Warnakulasuriya

Publisher: Springer Nature

Published: 2020-02-22

Total Pages: 449

ISBN-13: 3030323161

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This comprehensive multidisciplinary book examines all aspects of cancers of the mouth and oropharynx with the aim of equipping advanced students and practitioners in the early stages of specialist training with an up-to-date guide and reference. A multinational team of authors – all experts in the field of oral oncology – provide illuminating contributions on the full range of relevant topics: epidemiology, risk factors, clinical features, staging and prognostic factors, pathology, diagnostic techniques, disease prevention, surgery, radiotherapy, and chemotherapy. Molecular biology, molecular targeted therapies for advanced cases, and future diagnostic and prognostic applications of new technologies also receive careful attention. In providing a wealth of essential information and guidance in a practical format, the book will be a superb asset for senior graduate students in dentistry and specialist trainees in head and neck oncology. It will also be of high value for the many physicians, surgeons, pathologists, dentists, and specialists involved in the prevention, diagnosis, and management of squamous cell carcinomas of the oral cavity and oropharynx.

Tobacco Smoke and Involuntary Smoking

Tobacco Smoke and Involuntary Smoking PDF

Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Publisher: IARC

Published: 2004

Total Pages: 1476

ISBN-13: 9789283212836

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The IARC Monographs series publishes authoritative independent assessments by international experts of the carcinogenic risks posed to humans by a variety of agents, mixtures and exposures. They are a resource of information for both researchers and national and international authorities. This volume is particularly significant because tobacco smoke not only causes more deaths from cancer than any other known agent; it also causes more deaths from vascular and respiratory diseases. This volume contains all the relevant information on both direct and passive smoking. It is organised by first looking at the nature of agent before collecting the evidence of cancer in humans. This is followed by carcinogenicity studies on animals and then any other data relevant to an evaluation.

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