Renal and Metabolic Disorders

Renal and Metabolic Disorders PDF

Author: John A. Kellum

Publisher: Oxford University Press, USA

Published: 2013-02-07

Total Pages: 240

ISBN-13: 0199751609

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This book presents a road map of the interactions among metabolic, electrolyte, acid-base and endocrine problems and suggesting clear lines of action for the ICU clinician. Each chapter provides guidelines for understanding "how did we get here" and "what should we do now", as quickly and safely as possible.

Pediatric Nephrology

Pediatric Nephrology PDF

Author: Ellis D. Avner

Publisher: Springer Science & Business Media

Published: 2009-08-20

Total Pages: 2059

ISBN-13: 3540763279

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Here is an extensive update of Pediatric Nephrology, which has become the standard reference text in the field. It is global in perspective and reflects the international group of editors, who are well-recognized experts in pediatric nephrology. Within this text, the development of kidney structure and function is followed by detailed and comprehensive chapters on all childhood kidney diseases.

Metabolic Disorders and Critically Ill Patients

Metabolic Disorders and Critically Ill Patients PDF

Author: Carole Ichai

Publisher: Springer

Published: 2017-12-30

Total Pages: 477

ISBN-13: 3319640100

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The purpose of this book is to bring together the latest findings on metabolic disorders that are strongly implicated in various critically ill patients. Since the beginning of the 20th century, maintaining the "milieu intérieur" has been a major challenge for intensivists. In addition to considerable technological developments in intensive care units, important advances in our understanding of metabolic disorders observed in critically ill patients have been made during the 10 last years. Today, the intensivit can’t ignore these disorders when selecting the most appropriate treatment for an illness. Cellular metabolic abnormalities are responsible for systems and organ failures, so the modern approach of organ dysfunctions now includes prevention or treatment of such disorders. This book is a comprehensive tool, allowing the physician to understand, diagnose and treat these metabolic disorders. Water, electrolyte, acid-base, glycemic and endocrinologic problems, as well as metabolic abnormalities observed in renal, cerebral and hepatic failure are presented in different chapters. The last part of the book is devoted to modern nutritional concepts, the consequences of energy modifications, mitochondrial dysfunction, hypothermia, oxidative stress and ischemia reperfusion, which open the way for new therapies.​

Silva's Diagnostic Renal Pathology

Silva's Diagnostic Renal Pathology PDF

Author: Xin J. Zhou

Publisher: Cambridge University Press

Published: 2017-03-02

Total Pages: 691

ISBN-13: 1316613984

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An algorithmic approach to interpreting renal pathology, updated in light of recent advances in understanding and new classification schemes.

The Link Between Metabolic Syndrome and Chronic Kidney Disease: Focus on Diagnosis and Therapeutics, volume II

The Link Between Metabolic Syndrome and Chronic Kidney Disease: Focus on Diagnosis and Therapeutics, volume II PDF

Author: Ningning Hou

Publisher: Frontiers Media SA

Published: 2024-06-24

Total Pages: 160

ISBN-13: 2832550665

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Metabolic syndrome (MetS), including obesity, hyperglycemia, hyperlipidemia, hyperinsulinemia, are associated with disturbed energy homeostasis, limited whole-body insulin sensitivity, and an increased risk of cardiovascular and chronic kidney disease (CKD). The prospective and cross-sectional studies have shown a close association between the MetS and CKD. Chronic inflammation and vascular dysfunction are two key MetS-related etiological factors for renal injury. CKD is characterized by mitochondrial dysfunction, oxidative stress, and aberrant autophagy at the cellular level, which is also typical of metabolic disorders. However, the relationship and mechanism between metabolic disease and chronic kidney dysfunction still call for deeper understanding. This Research Topic aims to gather both Reviews and Original Research articles focused on discovering the truth behind the phenomenon that glucose and lipid metabolic disorders and obesity have important public health implications in terms of individuals with CKD. The studies covering new insights to determine the link between MetS-related immunity response and renal dysfunction will also be considered.

Nutritional Management of Renal Disease

Nutritional Management of Renal Disease PDF

Author: Joel D. Kopple

Publisher: Academic Press

Published: 2012-12-31

Total Pages: 833

ISBN-13: 0123919355

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This translational text offers in-depth reviews of the metabolic and nutritional disorders that are prevalent in patients with renal disease. Chapter topics address the growing epidemic of obesity and metabolic syndrome. Each chapter integrates basic and clinical approaches, from cell biology and genetics to diagnosis, patient management and treatment. Chapters in sections 4-7 include new illustrative case reports, and all chapters emphasize key concepts with chapter-ending summaries. New features also include the latest National Kidney Foundation Clinical Practice Guidelines on Nutrition in Chronic Renal Failure, the most recent scientific discoveries and the latest techniques for assessing nutritional status in renal disease, and literature reviews on patients who receive continuous veno-venous hemofiltration with or without dialysis. Provides a common language for nephrologists, nutritionists, endocrinologists, and other interested physicians to discuss the underlying research and translation of best practices for the nutritional management and prevention of renal disease Saves clinicians and researchers time in quickly accessing the very latest details on nutritional practice as opposed to searching through thousands of journal articles Correct diagnosis (and therefore correct treatment) of renal, metabolic, and nutritional disorders depends on a strong understanding of the molecular basis for the disease – both nephrologists and nutritionists will benefit Nephrologists and nutritionists will gain insight into which treatments, medications, and diets to use based on the history, progression, and genetic make-up of a patient Case Reports will offer an added resource for fellows, nutritionists, and dieticians who need a refresher course

Obesity and the Kidney

Obesity and the Kidney PDF

Author: Gunter Wolf

Publisher: Karger Medical and Scientific Publishers

Published: 2006

Total Pages: 269

ISBN-13: 3805581645

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We are currently facing an alarming obesity epidemic, with its well-known health consequences such as metabolic syndrome / type 2 diabetes, cardiovascular diseases, an increased incidence of certain types of cancer, musculoskeletal disorders and pulmonary diseases. Experimental and clinical evidence accumulated in recent years now suggests that obesity has also a major effect on renal structure and function. Since the adipocyte is considered a source of many hormones and cytokines, obesity has much more direct influences on renal function besides mediating hypertension: It can by itself induce renal disease such as focal segmental glomerulosclerosis, but also, more commonly, bring about progression of chronic renal diseases. The present volume is the first comprehensive compilation dedicated to this important topic, featuring discussions of pathophysiological as well as clinical aspects written by the leaders in this emerging field of research. It brings together pathophysiological concepts on how obesity influences renal structure and function, reviews the epidemiology of the problem and provides therapeutic suggestions. This publication is recommended for internists, nephrologists, hypertensiologists, cardiologists, and urologists treating patients with obesity and renal diseases. Furthermore, basic scientists such as renal physiologists, renal pathologists, pharmacologists, biochemists, and epidemiologists who want a comprehensive overview of the topic will also profit from this book.

Endocrine Disorders in Kidney Disease

Endocrine Disorders in Kidney Disease PDF

Author: Connie M. Rhee

Publisher: Springer

Published: 2019-03-13

Total Pages: 354

ISBN-13: 3319977652

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This comprehensive book examines the complex interplay between endocrine and kidney disorders, and how this inter-relationship impacts patients with chronic kidney disease. Authored by experts in areas of endocrinology and nephrology, chapters cover a variety of topics, including diabetes, metabolic syndrome, thyroid dysfunction, gonadal disorders, dyslipidemia, mineral bone disorders, obesity, and pituitary disorders. These comorbidities are thoroughly examined and provide the clinician, researcher, and trainee with a greater understanding of the impact of endocrine disorders on kidney disease patients, the ability to identify persistent gaps in knowledge for future investigation, and move closer towards the goal of improving the health and survival of the chronic kidney disease population.

Current Trends in the Diagnosis and Management of Metabolic Disorders

Current Trends in the Diagnosis and Management of Metabolic Disorders PDF

Author: Seth Kwabena Amponsah

Publisher: CRC Press

Published: 2023-12-14

Total Pages: 375

ISBN-13: 1003817343

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This volume provides an overview of the biochemical basis of metabolic diseases and molecular basis of chemical pathologies. Metabolic disorders occur when metabolic processes in the body are disrupted. They contribute a significant burden to human health globally. They can be congenital or acquired, for example, diabetes mellitus, obesity, metabolic syndrome, osteoporosis, osteopenia, mild-moderate hypovitaminosis D, erectile dysfunction, dyslipidemia, and thyroiditis. Metabolic disorders have gained significant importance due to the exponential increase in obesity worldwide. Early diagnosis of metabolic disorders is important in order to employ lifestyle and risk factor modification. Features: An overview of the biochemical basis of metabolic diseases and molecular basis of chemical pathologies Describes recent trends in diagnosis of metabolic disorders Discusses management and treatment of metabolic diseases Allows quick identification and retrieval of material by researchers learning the efficacy, associated dosage and toxicity of each of the classes of compounds Suitable globally for graduate and postgraduate students studying metabolic diseases