-PDF Download- Regulating Preimplantation Genetic Diagnosis In The United States EBOOK

Regulating Preimplantation Genetic Diagnosis in the United States

Author: M. Bayefsky

Publisher: Springer

Published: 2015-01-20

Total Pages: 181

ISBN-13: 1137515449

Reproductive technology allows us to test embryos' genes before deciding whether to transfer them to a woman's uterus. Embryo selection raises many ethical questions but is virtually unregulated in the United States. This comprehensive study considers the ethical, medical, political, and economic aspects of developing appropriate regulation.

Regulating Pre-implantation Genetic Diagnosis

Author: Sheila McLean

Publisher: Routledge

Published: 2013

Total Pages: 266

ISBN-13: 041568644X

DOWNLOAD EBOOK →

The successful achievement of pregnancies following pre-implantation genetic diagnosis (PGD) was first reported in April 1990. The technology is often used for patients who are at substantial risk of conceiving a pregnancy affected by a known genetic disorder, however from this technology other more controversial uses have arisen such as HLA typing to save the life of a sibling, gender selection for social reasons, the prevention of late onset diseases, or the prevention of diseases which may be genetically predisposed to developing such as breast cancer. The technology surrounding PGD is constantly developing, giving rise to new and unexpected consequences that create fresh ethical and legal dilemmas. Featuring internationally recognized experts in the field, this book critically explores the regulation of PGD and the broader legal and ethical issues associated with it. It looks at the regulatory situation in a number of jurisdictions including New Zealand, Australia and the United Kingdom, but it also explores a number of themes of wide significance including a historical consideration of PGD and its part in the creation of the "genetic embryo" as a political tool, the over regulation of PGD and the ethical difficulties in handling additional unexpected medical information yielded by new technologies. This book will be of particular interest to academics and students of law, medicine and ethics.

Predicting Probability

Author: Jaime S. King

Publisher:

Published: 2014

Total Pages: 78

ISBN-13:

DOWNLOAD EBOOK →

Government intervention into the reproductive decisions of individuals has been a significant source of tension and strife within American legal jurisprudence for the last century. This tension has caused many lawmakers in the United States to eschew attempts to regulate assisted reproductive technology, including preimplantation genetic diagnosis (PGD). PGD enables prospective parents to select embryos created through in vitro fertilization based on the presence of a genetic or chromosomal abnormality. Use of PGD has been limited due to technological constraints, expense, and moderate success rates.Recent advances in genetic testing technology will remove many of these obstacles, substantially increasing both the benefits available through PGD and its patient population. These advances will enable parents to do more than diagnose serious disorders in their potential offspring; they will be able to screen their embryos for hundreds of genetic and chromosomal characteristics at one time - preimplantation genetic screening (PGS).While these advances in reproductive genetic testing promise significant benefits, they also present risks to both individuals and society. Government intervention is warranted to ensure the quality and safety of assisted reproduction, including PGS, and to monitor its use for risks to individuals or society. The government should only intervene when the free exercise of individual reproductive autonomy threatens harm to others. This article proposes the creation of a federal regulatory body to license and monitor the practice of assisted reproduction and suggests a balancing framework for addressing conflicting interests in the use of PGS to screen for various genetic characteristics.

Preimplantation Genetic Diagnosis in Clinical Practice

Author: Tarek El-Toukhy

Publisher: Springer Science & Business Media

Published: 2013-11-08

Total Pages: 233

ISBN-13: 1447129482

DOWNLOAD EBOOK →

Preimplantation genetic diagnosis (PGD) is a rapidly advancing field of reproductive genetics. With the significant improvements achieved over the last few years in the understanding of many genetic diseases and in the techniques of molecular genetic testing, new genetic diseases are being added to the list of conditions amenable to PGD almost on a weekly basis. Therefore, the subject of PGD is becoming relevant to a much wider variety of medical disciplines and an increasing number of patients who may wish to know more about this treatment option. This unique book offers a comprehensive yet practical “user-friendly” guide to preimplantation genetic diagnosis (PGD). It provides understanding of and insight into the complete procedure, its recent clinical and laboratory developments and its future prospects, whilst offering an easy point of reference for patient enquiries. Concluding with perspectives on the ethical and social issues often encountered by healthcare professionals counselling patients with regards to PGD. Each chapter within Preimplantation Genetic Diagnosis in Clinical Practice is written by established authorities in their fields. An essential resource for PGD specialists and non-specialists, and for all practitioners working within the disciplines of fertility, reproductive medicine and medical genetics.

Regulating Preimplantation Genetic Diagnosis in the United States

Author: M. Bayefsky

Publisher: Springer

Published: 2015-01-20

Total Pages: 122

ISBN-13: 1137515449

DOWNLOAD EBOOK →

Heritable Human Genome Editing

Author: The Royal Society

Publisher: National Academies Press

Published: 2021-01-16

Total Pages: 239

ISBN-13: 0309671132

DOWNLOAD EBOOK →

Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.

Comparative Legal Frameworks for Pre-Implantation Embryonic Genetic Interventions

Author: Pin Lean Lau

Publisher: Springer

Published: 2019-08-01

Total Pages: 326

ISBN-13: 3030223086

DOWNLOAD EBOOK →

This book discusses the possibilities for the use of international human rights law (and specifically, international biomedical laws related to the protection of human rights and the human genome) to provide a guiding framework for the future regulation of genetic modifications applied to human embryos and other precursor materials, when these are made with the aim of implanting a genetically altered embryo in a woman. The significance and timeliness of the work derives from the recent availability of CRISPR/Cas9 and other gene editing tools, and from lacunae in international law regarding the legality of embryo modification with these tools and appropriate governance structures for the oversight of resulting practices. The emergence of improved genome editing tools like CRISPR/Cas9, holds the promise of eradicating genetic diseases in the near future. But its possible future applications with Pre-Implantation Genetic Diagnosis (PGD) raises a plethora of legal and ethical concerns about "remaking" future human beings. The work aims to address an urgent call, to embed these rising concerns about biomedical advancements into the fundamental tailoring of legal systems. Suitable regulatory approaches, coupled with careful reflection of global biomedical laws and individual constitutional systems must be explored. The Book analyzes the impact of reproductive biomedical technologies on the legal and ethical dimensions of regulatory frameworks in selected constitutional systems like the US, the UK, Australia, Malaysia and Thailand. Employing a comparative law methodology, the work reveals a dynamic intersection between legal cultures, socio-philosophical reasoning and the development of a human rights-based framework in bio-political studies. Navigating towards a truly internationalized biomedical approach to emerging technologies, it presents an understanding why a renegotiation and reinvigoration of a contemporary and "new" universal shared values system in the international human rights discourse is now necessary.

Genetic Dilemmas

Author: Dena S. Davis

Publisher: Oxford University Press

Published: 2010

Total Pages: 222

ISBN-13: 019537438X

DOWNLOAD EBOOK →

What limits the genetic choices parents make for their children? Is it okay to select the sex of our children, or for deaf parents to select deaf children? In this second edition of Genetic Dilemmas, Davis argues that parental reproductive autonomy should be limited by respect for the future autonomy of the children created by these measures. Praise for the first edition: "A thoughtful, timely and comprehensive look at genetics in the modern era by a recognized scholar of both their legal and humanistic implications. An excellent read!" -R. Alta Charo, Professor of Law and Medical Ethics, University of Wisconsin- Madison. "Dena Davis has been the most consistent and important voice insisting that we take seriously the concept of each child's right to an open future, and what respecting that right would mean for new technologies in genetics and reproduction. This engaging new book is the work of a thoughtful and humane scholar, and deserves a broad readership." -Thomas H. Murray, President of The Hastings Center "Dena Davis offers an engaging, informative and provocative argument in Genetic Dilemmas. Her primary accomplishment is to draw much-needed attention to the interests of the child in reproductive decision-making...she has succeeded admirably." -Mary Terrell White, Medical Humanities Review "People now face a dizzying array of choices about reproduction-from sex selection to cloning, from prenatal screening to genetic enhancement. In this engaging and path-breaking book, Dena Davis intelligently and compassionately explores the often-ignored impact of these choices on the children that are created and the society in which they will be raised." -Lori Andrews, Professor of Law, Chicago-Kent College of Law

Reflections on the Law and Ethics of Regulating Preimplantation Genetic Diagnosis in the United Kingdom

Author: Timothy Krahn

Publisher:

Published: 2013

Total Pages:

ISBN-13:

DOWNLOAD EBOOK →

Human Embryos and Preimplantation Genetic Technologies

Author: E. Scott Sills

Publisher: Academic Press

Published: 2019-05-01

Total Pages: 222

ISBN-13: 0128167440

DOWNLOAD EBOOK →

Human Embryos and Preimplantation Genetic Technologies: Ethical, Social, and Public Policy Aspects presents the first holistic analysis of PGD and PGS as it is practiced and regulated worldwide. In addition to scientific and technical aspects, the book provides perspectives on the ethical, legal, religious, policy and social implications of global assisted reproduction technologies, including in Africa, Asia, Europe, North and South America, and Australia. Chapters cover history, ethics, feminism, family dynamics, psychological and interpersonal factors, the current state of PGD and PGS in 20 different sovereign nations and religious communities, and provide an analysis of public policy concerns and future directions. Provides an in-depth discussion of PGD and PGS as practiced and regulated worldwide Offers an accessible resource for researchers, medical professionals, patients, regulators and policymakers seeking expert opinions on PGS and PGD Contains chapters contributed by international clinicians, researchers and thought leaders in the field of assisted reproductive technology