Randomization Tests

Randomization Tests PDF

Author: Eugene S. Edgington

Publisher:

Published: 1980

Total Pages: 312

ISBN-13:

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Random assignment; Calculating significance values; One-way analysis of variance and the independent t test; Repeated-measures analysis of variance and the correlated t test; Factorial designs; Multivariate designs; Correlation; Trend tests; One-subject randomization tests.

Randomization Tests, Fourth Edition

Randomization Tests, Fourth Edition PDF

Author: Eugene Edgington

Publisher: CRC Press

Published: 1995-07-25

Total Pages: 444

ISBN-13: 9780824796693

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The material in this work is organized in such as way as to illustrate how randomization tests are related to topics in parametric and traditional nonparametric statistics. The work extends the scope of applications by freeing tests from parametric assumptions without reducing data to ranks. This edition provides many new features, including more accessible terminology to clarify understanding, a current analysis of single-unit experiments as well as single-subject experiments, a discussion on how single-subject experiments relate to repeated-measures experiments and the use of randomized tests in single-patient research, and more.

Randomization Tests

Randomization Tests PDF

Author: Eugene Edgington

Publisher: CRC Press

Published: 2007-02-22

Total Pages: 364

ISBN-13: 1420011812

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The number of innovative applications of randomization tests in various fields and recent developments in experimental design, significance testing, computing facilities, and randomization test algorithms have necessitated a new edition of Randomization Tests. Updated, reorganized, and revised, the text emphasizes the irrelevance and implausibility of the random sampling assumption for the typical experiment in three completely rewritten chapters. It also discusses factorial designs and interactions and combines repeated-measures and randomized block designs in one chapter. The authors focus more attention on the practicality of N-of-1 randomization tests and the availability of user-friendly software to perform them. In addition, they provide an overview of free and commercial computer programs for all of the tests presented in the book. Building on the previous editions that have served as standard textbooks for more than twenty-five years, Randomization Tests, Fourth Edition includes downloadable resources of up-to-date randomization test programs that facilitate application of the tests to experimental data. This CD-ROM enables students to work out problems that have been added to the chapters and helps professors teach the basics of randomization tests and devise tasks for assignments and examinations.

Single-case and Small-n Experimental Designs

Single-case and Small-n Experimental Designs PDF

Author: John B. Todman

Publisher: Psychology Press

Published: 2001-03

Total Pages: 231

ISBN-13: 1135659354

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This book is a practical guide to help researchers draw valid causal inferences from small-scale clinical intervention studies. It should be of interest to teachers of, and students in, courses with an experimental clinical component, as well as clinical researchers. Inferential statistics used in the analysis of group data are frequently invalid for use with data from single-case experimental designs. Even non-parametric rank tests provide, at best, approximate solutions for only some single-case (and small-n ) designs. Randomization (Exact) tests, on the other hand, can provide valid statistical analyses for all designs that incorporate a random procedure for assigning treatments to subjects or observation periods, including single-case designs. These Randomization tests require large numbers of data rearrangements and have been seldom used, partly because desktop computers have only recently become powerful enough to complete the analyses in a reasonable time. Now that the necessary computational power is available, they continue to be under-used because they receive scant attention in standard statistical texts for behavioral researchers and because available programs for running the analyses are relatively inaccessible to researchers with limited statistical or computing interest. This book is first and foremost a practical guide, although it also presents the theoretical basis for Randomization tests. Its most important aim is to make these tests accessible to researchers for a wide range of designs. It does this by providing programs on CD-ROM that allow users to run analyses of their data within a standard package (Minitab, Excel, or SPSS) with which they are already familiar. No statistical or computing expertise is required to use these programs. This is the "new stats" for single-case and small-n intervention studies, and anyone interested in this research approach will benefit.

Randomization, Bootstrap and Monte Carlo Methods in Biology, Third Edition

Randomization, Bootstrap and Monte Carlo Methods in Biology, Third Edition PDF

Author: Bryan F.J. Manly

Publisher: CRC Press

Published: 2006-08-15

Total Pages: 488

ISBN-13: 9781584885412

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Modern computer-intensive statistical methods play a key role in solving many problems across a wide range of scientific disciplines. This new edition of the bestselling Randomization, Bootstrap and Monte Carlo Methods in Biology illustrates the value of a number of these methods with an emphasis on biological applications. This textbook focuses on three related areas in computational statistics: randomization, bootstrapping, and Monte Carlo methods of inference. The author emphasizes the sampling approach within randomization testing and confidence intervals. Similar to randomization, the book shows how bootstrapping, or resampling, can be used for confidence intervals and tests of significance. It also explores how to use Monte Carlo methods to test hypotheses and construct confidence intervals. New to the Third Edition Updated information on regression and time series analysis, multivariate methods, survival and growth data as well as software for computational statistics References that reflect recent developments in methodology and computing techniques Additional references on new applications of computer-intensive methods in biology Providing comprehensive coverage of computer-intensive applications while also offering data sets online, Randomization, Bootstrap and Monte Carlo Methods in Biology, Third Edition supplies a solid foundation for the ever-expanding field of statistics and quantitative analysis in biology.

Randomization, Masking, and Allocation Concealment

Randomization, Masking, and Allocation Concealment PDF

Author: Vance Berger

Publisher: CRC Press

Published: 2017-10-30

Total Pages: 251

ISBN-13: 1315305100

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Randomization, Masking, and Allocation Concealment is indispensable for any trial researcher who wants to use state of the art randomization methods, and also wants to be able to describe these methods correctly. Far too often the subtle nuances that distinguish proper randomization from flawed randomization are completely ignored in trial reports that state only that randomization was used, with no additional information. Experience has shown that in many cases, the type of randomization that was used was flawed. It is only a matter of time before medical journals and regulatory agencies come to realize that we can no longer rely on (or publish) flawed trials, and that flawed randomization in and of itself disqualifies a trial from being robust or high quality, even if that trial is of high quality otherwise. This book will help to clarify the role randomization plays in ensuring internal validity, and in drawing valid inferences from the data. The various chapters cover a variety of randomization methods, and are not limited to the most common (and most flawed) ones. Readers will come away with a profound understanding of what constitutes a valid randomization procedure, so that they can distinguish the valid from the flawed among not only existing methods but also methods yet to be developed.

Randomization, Bootstrap and Monte Carlo Methods in Biology

Randomization, Bootstrap and Monte Carlo Methods in Biology PDF

Author: Bryan F.J. Manly

Publisher: CRC Press

Published: 2020-07-20

Total Pages: 241

ISBN-13: 1000080544

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Modern computer-intensive statistical methods play a key role in solving many problems across a wide range of scientific disciplines. Like its bestselling predecessors, the fourth edition of Randomization, Bootstrap and Monte Carlo Methods in Biology illustrates a large number of statistical methods with an emphasis on biological applications. The focus is now on the use of randomization, bootstrapping, and Monte Carlo methods in constructing confidence intervals and doing tests of significance. The text provides comprehensive coverage of computer-intensive applications, with data sets available online. Features Presents an overview of computer-intensive statistical methods and applications in biology Covers a wide range of methods including bootstrap, Monte Carlo, ANOVA, regression, and Bayesian methods Makes it easy for biologists, researchers, and students to understand the methods used Provides information about computer programs and packages to implement calculations, particularly using R code Includes a large number of real examples from a range of biological disciplines Written in an accessible style, with minimal coverage of theoretical details, this book provides an excellent introduction to computer-intensive statistical methods for biological researchers. It can be used as a course text for graduate students, as well as a reference for researchers from a range of disciplines. The detailed, worked examples of real applications will enable practitioners to apply the methods to their own biological data.

Randomization in Clinical Trials

Randomization in Clinical Trials PDF

Author: William F. Rosenberger

Publisher: John Wiley & Sons

Published: 2015-11-23

Total Pages: 284

ISBN-13: 1118742249

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Praise for the First Edition “All medical statisticians involved in clinical trials should read this book…” - Controlled Clinical Trials Featuring a unique combination of the applied aspects of randomization in clinical trials with a nonparametric approach to inference, Randomization in Clinical Trials: Theory and Practice, Second Edition is the go-to guide for biostatisticians and pharmaceutical industry statisticians. Randomization in Clinical Trials: Theory and Practice, Second Edition features: Discussions on current philosophies, controversies, and new developments in the increasingly important role of randomization techniques in clinical trials A new chapter on covariate-adaptive randomization, including minimization techniques and inference New developments in restricted randomization and an increased focus on computation of randomization tests as opposed to the asymptotic theory of randomization tests Plenty of problem sets, theoretical exercises, and short computer simulations using SAS® to facilitate classroom teaching, simplify the mathematics, and ease readers’ understanding Randomization in Clinical Trials: Theory and Practice, Second Edition is an excellent reference for researchers as well as applied statisticians and biostatisticians. The Second Edition is also an ideal textbook for upper-undergraduate and graduate-level courses in biostatistics and applied statistics. William F. Rosenberger, PhD, is University Professor and Chairman of the Department of Statistics at George Mason University. He is a Fellow of the American Statistical Association and the Institute of Mathematical Statistics, and author of over 80 refereed journal articles, as well as The Theory of Response-Adaptive Randomization in Clinical Trials, also published by Wiley. John M. Lachin, ScD, is Research Professor in the Department of Epidemiology and Biostatistics as well as in the Department of Statistics at The George Washington University. A Fellow of the American Statistical Association and the Society for Clinical Trials, Dr. Lachin is actively involved in coordinating center activities for clinical trials of diabetes. He is the author of Biostatistical Methods: The Assessment of Relative Risks, Second Edition, also published by Wiley.

Randomization in Clinical Trials

Randomization in Clinical Trials PDF

Author: William F. Rosenberger

Publisher: John Wiley & Sons

Published: 2015-10-28

Total Pages: 284

ISBN-13: 1118742370

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Praise for the First Edition “All medical statisticians involved in clinical trials should read this book...” - Controlled Clinical Trials Featuring a unique combination of the applied aspects of randomization in clinical trials with a nonparametric approach to inference, Randomization in Clinical Trials: Theory and Practice, Second Edition is the go-to guide for biostatisticians and pharmaceutical industry statisticians. Randomization in Clinical Trials: Theory and Practice, Second Edition features: Discussions on current philosophies, controversies, and new developments in the increasingly important role of randomization techniques in clinical trials A new chapter on covariate-adaptive randomization, including minimization techniques and inference New developments in restricted randomization and an increased focus on computation of randomization tests as opposed to the asymptotic theory of randomization tests Plenty of problem sets, theoretical exercises, and short computer simulations using SAS® to facilitate classroom teaching, simplify the mathematics, and ease readers’ understanding Randomization in Clinical Trials: Theory and Practice, Second Edition is an excellent reference for researchers as well as applied statisticians and biostatisticians. The Second Edition is also an ideal textbook for upper-undergraduate and graduate-level courses in biostatistics and applied statistics. William F. Rosenberger, PhD, is University Professor and Chairman of the Department of Statistics at George Mason University. He is a Fellow of the American Statistical Association and the Institute of Mathematical Statistics, and author of over 80 refereed journal articles, as well as The Theory of Response-Adaptive Randomization in Clinical Trials, also published by Wiley. John M. Lachin, ScD, is Research Professor in the Department of Epidemiology and Biostatistics as well as in the Department of Statistics at The George Washington University. A Fellow of the American Statistical Association and the Society for Clinical Trials, Dr. Lachin is actively involved in coordinating center activities for clinical trials of diabetes. He is the author of Biostatistical Methods: The Assessment of Relative Risks, Second Edition, also published by Wiley.

Single-case and Small-n Experimental Designs

Single-case and Small-n Experimental Designs PDF

Author: Pat Dugard

Publisher: Taylor & Francis

Published: 2012-04-27

Total Pages: 306

ISBN-13: 1136588477

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This practical guide explains the use of randomization tests and provides example designs and macros for implementation in IBM SPSS and Excel. It reviews the theory and practice of single-case and small-n designs so readers can draw valid causal inferences from small-scale clinical studies. The macros and example data are provided on the book’s website so that users can run analyses of the text data as well as data from their own studies. The new edition features: More explanation as to why randomization tests are useful and how to apply them. More varied and expanded examples that demonstrate the use of these tests in education, clinical work and psychology. A website with the macros and datasets for all of the text examples in IBM SPSS and Excel. Exercises at the end of most chapters that help readers test their understanding of the material. A new glossary that defines the key words that appear in italics when they are first introduced. A new appendix that reviews the basic skills needed to do randomization tests. New appendices that provide annotated SPSS and Excel macros to help readers write their own or tinker with the ones provided in the book. The book opens with an overview of single case and small n designs -- why they are needed and how they differ from descriptive case studies. Chapter 2 focuses on the basic concepts of randoization tests. Next how to choose and implement a randomization design is reviewed including material on how to perform the randomizations, how to select the number of observations, and how to record the data. Chapter 5 focuses on how to analyze the data including how to use the macros and understand the results. Chapter 6 shows how randomization tests fit into the body of statistical inference. Chapter 7 discusses size and power. The book concludes with a demonstration of how to edit or modify the macros or use parts of them to write your own. Ideal as a text for courses on single-case, small n design, and/or randomization tests taught at the graduate level in psychology (especially clinical, counseling, educational, and school), education, human development, nursing, and other social and health sciences, this inexpensive book also serves as a supplement in statistics or research methods courses. Practitioners and researchers with an applied clinical focus also appreciate this book’s accessible approach. An introduction to basic statistics, SPSS, and Excel is assumed.